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Early signs that adult bone-marrow stem cells could regenerate brain tissue (p 1432)
Findings of a preliminary study in this week's issue of THE LANCET suggest that transplanted adult bone-marrow cells could regenerate nerve cells in the brains of human stem-cell recipients. These early findings, if confirmed in future research, have implications for the treatment of neurodegenerative disorders such as Parkinson's disease. Ethical... view more... (2004-04-28)
Human stem cells delay start of Lou Gehrig's disease in rats
Researchers at Johns Hopkins have shown that transplanting human stem cells into spinal cords of rats bred to duplicate Lou Gehrig's disease delays the start of nerve cell damage typical of the disease and slightly prolongs life. view more (2006-10-16)
Protein protects embryonic stem cells' versatility and self-renewal
A protein known as REST blocks the expression of a microRNA that prevents embryonic stem cells from reproducing themselves and causes them to differentiate into specific cell types, scientists at The University of Texas M. D. Anderson Cancer Center report in the journal Nature. view more (2008-03-24)
Trial at Jefferson shows new drug may help cancer patients who need stem cell transplants
A new drug may help cancer patients mobilize the cells necessary to restore their blood-forming system after high-dose chemotherapy, according to results from a clinical trial at the Kimmel Cancer Center at Thomas Jefferson University Hospital in Philadelphia and at other centers across the nation. view more (2005-09-09)
Stanford doctors advance in bid to turn mice stem cells into blood vessels
Researchers at the Stanford University School of Medicine have taken a first step toward growing blood vessels from stem cells that could eventually be transplanted into living organisms. view more (2006-06-22)
Expression of 'Blimp1' gene leads to the discovery of cells responsible for skin's sebaceous gland
Mice may not get zits, but they do have oily skin. This week, new research on mice from Rockefeller University shows how the cells responsible for oil production develop, and uncovers clues about how stem cells renew and differentiate. view more (2006-08-11)
MIT bioengineer advances survival, promise of adult stem cells
MIT researchers have developed a technique to encourage the survival and growth of adult stem cells, a step that could help realize the therapeutic potential of such cells. view more (2007-02-28)
Chemical cues turn embryonic stem cells into cerebellar neurons
In order to differentiate and specialize, stem cells require very specific environmental cues in a very specific order, and scientists have so far been unable to prod them to go through each of the necessary steps. view more (2007-03-15)
Role of the nervous system in regulating stem cells discovered
New study by Mount Sinai researchers may lead to improved stem cell therapies for patients with compromised immune systems due to intensive cancer therapy or autoimmune disease. view more (2006-01-27)
Stem-cell transfer could improve cardiac functioning after heart attack (pp 121, 141)
Results of a randomised trial in this week's issue of THE LANCET suggest that the transfer of adult stem cells derived from bone marrow could improve cardiac functioning after heart attack. Evidence is emerging that adult stem cells from bone marrow have therapeutic potential for restoring cardiac cells among people who have had heart attack.... view more... (2004-07-07)
CSHL scientists identify and repress breast cancer stem cells in mouse tissue
By manipulating highly specific gene-regulating molecules called microRNAs, scientists at Cold Spring Harbor Laboratory (CSHL) report that they have succeeded in singling out and repressing stem-like cells in mouse breast tissue - cells that are widely thought to give rise to cancer. view more (2007-12-18)
Scientists develop novel method to generate functional hepatocytes for drug testing
Scientists have for the first time produced liver cells from adult skin cells using the induced pluripotent stem cell (iPSC) technology. view more (2009-10-21)
Wealth of genomic hotspots discovered in embryonic stem cells
In a paper published in Cell on June 13, 2008, Singapore scientists at the Genome Institute of Singapore (GIS) and the National University of Singapore (NUS) unveil an atlas that showing the location of "genomic hotspots" of essential protein "switches" (transcription factors) that are critical for maintaining the embryonic... view more... (2008-06-16)
Bio-engineering of blood vessels
Blood vessel prostheses work best when the biochemical and mechanical properties match reality as much as possible and when they are made of biodegradable material. To this end tissue technologists grow natural vascular wall cells, endothelial cells, in a biodegradable tube made of collagen. According to Professor Istv'¡n Vermes tissue... view more... (2002-04-16)
Protein is Key to Embryonic Stem Cell Differentiation
Investigators at Burnham Institute for Medical Research (Burnham) have learned that a protein called Shp2 plays a critical role in the pathways that control decisions for differentiation or self-renewal in both human embryonic stem cells (hESCs) and mouse embryonic stem cells (mESCs). view more (2009-03-19)
Xie Lab uncovers molecular machinery related to stem cell fate
The Stowers Institute's Xie Lab has revealed how the BAM protein affects germline stem cell differentiation and how it is involved in regulating the quality of stem cells through intercellular competition. view more (2009-06-29)
Scientists produce neurons from human skin
Scientists from Université Laval's Faculty of Medicine have succeeded in producing neurons in vitro using stem cells extracted from adult human skin. view more (2007-02-23)
Ethical Guidelines Presented for Swedish Stem Cell Research
In brief, the guidelines mean that researchers may take stem cells from embryos that can no longer be used for further IVF treatment. Moreover, the creation of embryos by somatic cell nuclear transfer (therapeutic cloning) to get access to stem cells is deemed to be ethically defensible. The reason for this is the prospect of major long-term... view more... (2001-12-04)
Stem cells replace stroke-damaged tissue in rats
Effective stem cell treatment for strokes has taken a significant step forward today (09 March) as scientists reveal how they have replaced stroke-damaged brain tissue in rats. view more (2009-03-09)
Scientists closer to making implantable bone material, thanks to new research
Scientists are closer to understanding how to grow replacement bones with stem cell technology, thanks to research published today in the journal Nature Materials. view more (2009-07-27)
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