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New study overturns orthodoxy on how macrophages kill bacteria
For decades, microbiologists assumed that macrophages, immune cells that can engulf and poison bacteria and other pathogens, killed microbes by damaging their DNA. A new study from the University of Illinois disproves that. view more (2009-04-28)
Researchers Create Model of Cancer-Preventing Enzyme, Study How It Works
Proline dehydrogenase is important because it plays a role in apoptosis, the process of cell death, by enabling the creation of superoxide, a highly reactive electron-rich oxygen species. view more (2007-05-14)
Toxic molecule may help birds 'see' north and south
Researchers at the University of Illinois report that a toxic molecule known to damage cells and cause disease may also play a pivotal role in bird migration. view more (2009-06-23)
Tiptoe through the tulips
Scientists have discovered that plant leaves activate defence mechanisms against plant eating insects within twenty seconds of an insect walking across them. Dr Alan Bown will be presenting the results of his footsteps research at the Society for Experimental Biology conference on Tuesday 9 April. view more (2002-04-04)
Knowing how ketamine impairs brain circuitry may lead to new therapies for schizophrenia
Scientists know that the drug ketamine - street name "Special K" - can induce schizophrenia-like symptoms in drug abusers. Ketamine is also used as an anesthetic and, more recently, as an antidepressant - raising concerns by researchers at the University of California, San Diego (UCSD) School of Medicine, who have found that ketamine... view more... (2007-12-07)
Antioxidant tempol prevents pre-eclampsia, decreases fetal mortality in mice
The antioxidant tempol prevents the onset of pre-eclampsia in pregnant mice, a finding that further implicates oxidative stress in the illness, which is widespread among pregnant women. view more (2006-04-03)
Structure of cog at the hub of metabolism reveals anti-ageing function
The structure of a key energy-releasing enzyme found in all animals is designed to minimise free radical production, an international team of researchers report in the journal Science today. In a startling feat of structural biology, the team visualised the entire molecular structure of succinate dehydrogenase in the bacterium E. coli, allowing... view more... (2003-01-30)
UCLA, Italian chemists move closer to solving Lou Gehrig's disease mystery
Chemists from UCLA and the University of Florence in Italy may have solved an important mystery about a protein that plays a key role in a particular form of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, a progressive, fatal neurodegenerative disorder that strikes without warning. view more (2007-06-28)
Boston University biomedical engineers find chink in bacteria's armor
Biomedical researchers at Boston University's College of Engineering may have discovered the path toward developing better drugs capable of defeating so-called "superbugs," bacteria that have developed resistance to common antibiotics. view more (2007-09-07)
Sleep Apnea Increases Heart Disease Risk
Obstructive sleep apnea, or periodic interruptions in breathing throughout the night, thickens sufferers' blood vessels. Moreover, it increases the risk of several forms of heart and vascular disease. view more (2009-05-05)
Protein plays Jekyll and Hyde role in Lou Gehrig's disease
Amyotrophic lateral sclerosis (ALS), more commonly known as Lou Gehrig's disease, is a fatal neurodegenerative disease caused by the death of motor neurons in the brain and spinal cord that control muscle movements from walking and swallowing to breathing. In a groundbreaking study this week in PLoS Biology, Brandeis and Harvard Medical School... view more... (2008-07-29)
Cancer-causing gut bacteria exposed
Normal gut bacteria are thought to be involved in colon cancer but the exact mechanisms have remained unknown. Now, scientists from the USA have discovered that a molecule produced by a common gut bacterium activates signalling pathways that are associated with cancer cells. view more (2008-09-22)
Anti-aging hormone reduces reactive oxygen species
Scientists recently discovered an anti-aging hormone called Klotho. Now, a new study shows that this protein acts by increasing the cell's ability to detoxify harmful reactive oxygen species. view more (2005-11-04)
The secret to long life
What controls lifespan? An intriguing new twist is emerging from the work of Professor Heinz Osiewacz (Frankfurt) using a short-lived fungus. He has discovered that when there is a mutation in the gene, Grisea, that controls copper uptake into cells, the fungus can live 60% longer than their normal wild-types. Why is this? Professor Osiewacz... view more... (2001-04-04)
Biodegradable polymers show promise for improving treatment of acute inflammatory diseases
A family of biodegradable polymers called polyketals and their derivatives may improve treatment for such inflammatory illnesses as acute lung injury, acute liver failure and inflammatory bowel disease by delivering drugs, proteins and snips of ribonucleic acid to disease locations in the body. view more (2008-08-21)
The healing power of Hydrogen Peroxide
Hydrogen peroxide is usually used for cleansing scratches and cuts. However, this is not the only one possible application of this substance in medicine. The vapor of a low-concentrated peroxide solution containing oxygen radicals can be used as an inhalant for an additional treatment of many illnesses. This has been established by the research... view more... (2002-04-19)
Neutrophils in rheumatoid arthritis: How to lessen inflammation but still fight infection
Neutrophils, which quickly congregate at the sites of infection and inflammation, are capable of ingesting microorganisms or other particles. view more (2006-06-16)
Hypoxia training suppresses harmful cardiac nitric oxide production during heart attack
Researchers at the University of North Texas Health Science Center, Fort Worth, Texas have demonstrated that, contrary to prevailing dogma, hypoxia can be remarkably beneficial to the heart. These discoveries, to be reported in the June 2008 issue of Experimental Biology and Medicine, may lead to a new paradigm to protect hearts of patients at... view more... (2008-05-27)
Dysfunctional protein dynamics behind neurological disease?
Researchers at Lund University, Sweden, have taken a snapshot of proteins changing shape, sticking together and creating structures that are believed to trigger deadly processes in the nervous system. view more (2009-10-14)
Genetics of ALS progression
An upcoming paper from Drs. Hidenori Ichijo and Hideki Nishitoh (The University of Tokyo) and colleagues lends new and valuable insight into the genetics of ALS. view more (2008-06-02)
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