Suppressor Gene Current Events | Suppressor Gene News
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WT1, male fertility and tumorigenesis
Detailed in an upcoming report in G&D, Dr. Miles Wilkinson and colleagues use a new tissue-specific RNAi approach they developed to identify a novel postnatal role for the Wilms' tumor 1 (WT1) tumor suppressor in spermatogenesis. view more (2006-01-16)
Breast cancer amongst young women
Breast cancer is the most common and the second-most fatal malignant tumour amongst women who live in industrialised countries. Moreover, when present in young women, it would appear that a genetic predisposition is involved. This predisposition can be due to a number of causes and, amongst the most common, lie the alterations in the gene... view more... (2003-11-14)
New Discovery Raises Doubts About Use of Certain Targeted Therapies in Bladder Cancer
Researchers at the University of Virginia Health System have found that one of the genes commonly thought to promote the growth and spread of some types of cancers is in fact beneficial in bladder cancer - a major discovery that could significantly alter the way bladder cancers are treated in the future. view more (2009-03-26)
Cancer researchers found a new mechanism potentially explaining evolution of signalling pathways
Cancer researchers at the University of Helsinki, in trying to find a novel tumor suppressor gene, instead found an important evolutionary change that occurred in a key developmental signalling pathway. view more (2006-02-08)
A tumor suppressor that promotes cancer cell growth?
Researchers have shown that the tumor suppressor gene H-REV107-1 may actually stimulate tumor progression in some non-small cell lung carcinomas. view more (2006-10-09)
Researchers identify new drug targets for cancer
Solving a 100-year-old genetic puzzle, researchers at the University of California, San Diego (UCSD) School of Medicine have determined that the same genetic mechanism that drives tumor growth can also act as a tumor suppressor. view more (2007-01-02)
New test proves effective in more cancers
Avantogen Limited (ACU:ASX) today announced that cancer researchers at Perth's Telethon Institute for Child Health Research (TICHR) and Avantogen Limited have achieved an important milestone towards more individually targeted and effective treatments for cancer patients. view more (2005-10-07)
Cancer: Another step towards medication
The gene Myc is an important factor for the growth of organisms by cell division. It causes the production of a protein which, as a transcription factor, controls the expression of up to 15 % of all human genes. view more (2009-03-18)
Gene packaging tells story of cancer development
To decipher how cancer develops, Johns Hopkins Kimmel Cancer Center investigators say researchers must take a closer look at the packaging. view more (2008-12-05)
Multicenter study nets new lung tumor-suppressor gene
Collaborating scientists in Boston and North Carolina have found that a particular gene can block key steps of the lung cancer process in mice. view more (2007-08-06)
New insights into the regulation of PTEN tumor suppression function
The PTEN tumor suppressor gene controls numerous biological processes including cell proliferation, cell growth and death. But PTEN is frequently lost or mutated; in fact, alteration of the gene is so common among various types of human cancer that PTEN has become one of the most frequently mutated of all tumor suppressors. view more (2008-08-21)
Study details regulation of vital tumor suppressor gene p53
So vital is the p53 tumor suppressor gene in controlling cancer that its dysfunction is linked to more than half of human cancers. view more (2007-09-06)
Viral oncoprotein inactivation of p53
A group of scientists led by USC researcher Dr. Xiaojiang Chen lend structural insight into tumor suppressor inactivation by a viral oncoprotein. view more (2006-09-01)
Growth gene linked to cancer
Growth gene linked to cancer view more (1999-12-16)
Cancer immunoresistance linked to loss of tumor suppressor gene
Cancer immunoresistance may be partially due to loss of a well-known tumor suppressor gene, according to new research led by Andrew T. Parsa, MD, PhD, assistant professor of neurological surgery at the University of California, San Francisco. view more (2006-12-11)
Cold Spring Harbor Laboratory scientists discover new gene that prevents multiple types of cancer
A decades-old cancer mystery has been solved by researchers at Cold Spring Harbor Laboratory (CSHL). "We not only found a critical tumor suppressor gene, but have revealed a master switch for a tumor suppressive network that means more targeted and effective cancer therapy in the future," said CSHL Associate Professor Alea Mills, Ph.D.... view more... (2007-02-12)
New journal shows half-broken gene is enough to cause cancer
Tumour suppressor genes do not necessarily require both alleles to be knocked out before disease phenotypes are expressed. Research published in BioMed Central's new open access journal PathoGenetics reveals that only one allele of SMAD4 has to be damaged to put a person at risk of pancreatic and colorectal cancer. view more (2008-11-04)
Molecular 'clock' could predict risk for developing breast cancer
A chemical reaction in genes that control breast cancer provides a molecular clock that could one day help researchers more accurately determine a woman's risk for developing breast cancer and provide a new approach for treatment, UT Southwestern Medical Center researchers have found. view more (2008-05-14)
Study identifies new tumor suppressor
A protein called HLJ1 may work as a novel tumor suppressor in non-small-cell lung carcinoma. view more (2006-06-21)
'1-hit' event provides new opportunity for colon cancer prevention, say Fox Chase researchers
More than 30 years ago, Alfred Knudson Jr., M.D., Ph.D., revolutionized the field of cancer genetics by showing that a person must lose both their paternal and maternal copies of a particular class of cancer-inhibiting genes, called tumor-suppressor genes, in order to develop cancer. view more (2008-09-15)
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