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Capturing the birth of a synapse
Researchers have identified the locking mechanism that allows some neurons to form synapses to pass along essential information. view more (2009-05-27)
New understanding of basic units of memory
A molecular "recycling plant" permits nerve cells in the brain to carry out two seemingly contradictory functions - changeable enough to record new experiences, yet permanent enough to maintain these memories over time. view more (2007-09-20)
MIT: Missing protein may be key to autism
A missing brain protein may be one of the culprits behind autism and other brain disorders, researchers at MIT's Picower Institute for Learning and Memory report in the Dec. 6 issue of Neuron. view more (2007-12-06)
Building memories with actin
Memories aren't made of actin filaments. But their assembly is crucial for long-term potentiation (LTP), an increase in synapse sensitivity that researchers think helps to lay down memories. view more (2009-07-13)
Tiny RNA molecules fine-tune the brain's synapses
Non-coding regions of the genome - those that don't code for proteins - are now known to include important elements that regulate gene activity. view more (2006-01-19)
Huntington's disease problem start early
The damaging effects of the mutated protein involved in Huntington's disease take place earlier in cell life than previously believed, said researchers from Baylor College of Medicine in Houston in a report that appears in the current edition of the journal Neuron. view more (2008-01-10)
UCSF study points to link to neurodegenerative disease target
The findings are relevant for ongoing research in identifying causes and developing treatments for neuromuscular neurodegenerative diseases in humans, such as amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. view more (2005-09-02)
Scientists capture the first image of memories being made
The ability to learn and to establish new memories is essential to our daily existence and identity; enabling us to navigate through the world. view more (2009-06-19)
Communication within the immune system:Immune synapses cannot function without ZAP-70
A familial form of severe combined immune deficiency (SCID) is caused by anomalies of an enzyme called ZAP-70. If ZAP-70 is lacking or does not work, the T-cells, which play a key role in the mechanisms of immune defense, are no longer functional. Affected children therefore catch infections as soon as they are exposed to pathogenic... view more... (2002-10-24)
Proteins anchor memories in our brain
A University of Utah study suggests that memories are held in our brains because certain proteins serve as anchors, holding other proteins in place to strengthen synapses, which are connections between nerve cells. view more (2006-11-22)
Study pinpoints key mechanism in brain development, raising question about use of antiseizure drug
Researchers at the Stanford University School of Medicine have identified a key molecular player in guiding the formation of synapses - the all-important connections between nerve cells - in the brain. view more (2009-10-09)
1 small step for neurons, 1 giant leap for nerve cell repair
The repair of damaged nerve cells is a major problem in medicine today. A new study by researchers at the Montreal NeurologicaI Institute and Hospital (The Neuro) and McGill University, is a significant advance towards a solution for neuronal repair. view more (2009-10-08)
Membrane fusion at the synapse: Janus faced synaptotagmin-1 helps to keep the fast pace
Imagine a bathtub with two soap bubbles colliding but never fusing. Then you add detergent, and the surface of the water goes flat as the walls of the bubbles collapse and merge. view more (2008-10-30)
Research clarifies how brain replenishes memory-making molecules
Memory formation is thought to involve a strengthening of the communication between neurons in the part of the brain known as the hippocampus. view more (2005-12-22)
NIAID scientists identify new cellular receptor for HIV
A cellular protein that helps guide immune cells to the gut has been newly identified as a target of HIV when the virus begins its assault on the body's immune system, according to researchers from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH). view more (2008-02-11)
Researchers find molecule that may hold key to learning and memory
Independent research teams from Harvard Medical School and Children's Hospital Boston have identified a master protein that sheds light on one of neurobiology's biggest mysteries-how neurons change as a result of individual experiences. view more (2006-02-22)
CSHL researchers unravel how a protein helps nerve cells recycle synaptic vesicles
Brain cells, or neurons, transmit electrical signals efficiently only when they recycle tiny cellular sacs that store signaling chemicals called neurotransmitters. view more (2009-06-03)
New Brandeis research sheds light on memory by erasing it
For years, scientists have studied the molecular basis of memory storage, trying to find the molecules that store memory, just as DNA stores genetic memory. view more (2007-05-09)
Researchers learn more about genetic mutation linked to autism
University of Iowa researchers have learned more about a genetic mutation that contributes to autism. The mutation occurred in sperm cells of a father, who does not have autism, but passed the condition on to two of his children. view more (2007-05-04)
CSHL links activity in brain synapses and developmental abnormalities with schizophrenia gene
Cold Spring Harbor Laboratory (CSHL) researchers have identified a function of neuregulin1 (NRG1), a gene previously linked to schizophrenia but whose role in the disease was unknown. view more (2007-05-25)
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