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Researchers create safer alternative to heparin
Robert Linhardt has spent years stitching together minuscule carbohydrates to build a more pure and safer alternative to the commonly used and controversial blood thinner heparin.   view more (2008-08-18)

UNC School of Pharmacy researchers create new synthetic heparin
Researchers at the University of North Carolina at Chapel Hill have patented a synthetic version of the drug heparin, called Recomparin, that is less complex chemically and should be easier to produce than previous forms.   view more (2007-09-24)

Deadly dose: Rensselaer heparin expert helps uncover source of lethal contamination
The mysterious death of patients around the world following a routine dosage of the common blood thinner, heparin, sent researchers on a frantic search to uncover what could make the standard drug so toxic.   view more (2008-04-28)

Heparin prepared synthetically could replace animal-derived drug
Researchers at Rensselaer Polytechnic Institute and University of North Carolina at Chapel Hill have discovered an alternative way to produce heparin, a drug commonly used to stop or prevent blood from clotting.   view more (2006-02-07)

Simple new method detects contaminants in life-saving drug
The blood-thinning drug heparin is highly effective when used to prevent and treat blood clots in veins, arteries and lungs, but earlier this year its reputation as a lifesaver was sullied when contaminated heparin products caused serious allergic reactions that led to a large number of deaths.   view more (2008-11-18)

Less expensive anti-clotting medication appears as safe and effective as more expensive treatment
Subcutaneous (beneath the skin) injection of the original and less expensive form of the anticoagulant medication heparin is as effective and safe as subcutaneous administration of the newer and more expensive low-molecular-weight heparin for treatment of venous thromboembolism (blood clots in the... view more (2006-08-23)

Chemists move closer toward developing safer, fully-synthetic form of heparin
Chemists are reporting a major advance toward developing a safer, fully-synthetic version of heparin, the widely used blood thinner now produced from pig intestines. The U. S. Food and Drug Administration last spring linked contaminated batches of the animal-based product, imported from China, to... view more (2008-08-18)

Blood-compatible nanoscale materials possible using heparin
Researchers from Rensselaer Polytechnic Institute have engineered nanoscale materials that are blood compatible using heparin, an anticoagulant. The heparin biomaterials have potential for use as medical devices and in medical treatments such as kidney dialysis.   view more (2006-05-08)

Blood clots can be treated by injections at home
Treatment of blood clots in the deep veins of the legs or the lungs with an older, less expensive form of the anticoagulant medication heparin can be just as safe and effective as similar treatment with a newer and more expensive heparin.   view more (2006-08-23)

Reduced Risk Of Recurrent Heart Attack With Anticoagulant Drug
Results of a study in this week's issue of THE LANCET show that patients given the anticoagulant drug, bivalirudin, had a reduced risk of recurrent heart attack compared with patients given conventional treatment with heparin. The combination of anticoagulant therapies (fibrinolytic therapy and the... view more (2001-11-28)

NEW SYNTHETIC ANTITHROMBOTIC DRUG COULD REDUCE DVT RISK AFTER HIP SURGERY (pp 1710, 1715, 1721)
Two studies in this week's issue of THE LANCET highlight how a new class of synthetic antithrombotic drug could be more effective than conventional therapy in reducing the risk of potentially fatal blood clots associated with hip-replacement surgery.    Between 16 and 30% of patients... view more (2002-05-15)

Heparin antibodies may pose risk in heart surgery patients
New research suggests that patients who develop antibodies to the anti-clotting drug heparin nearly double their risk of death or serious complication after heart surgery.   view more (2005-12-05)

New Combination Therapy Could Reduce Ischaemia After Heart Attack (p 605)
Encouraging results from a fast-track study published in this week's issue of THE LANCET suggest a new therapeutic strategy for reducing ischaemic complications (coronary artery blockage) after heart attack. The treatment of acute heart attack requires combination of several therapies. Fibrinolytic... view more (2001-08-22)

Mayo researchers explore reasons for complications with kidney failure patients
Mayo Clinic researchers searching for explanations of high mortality rates among kidney failure patients undergoing hemodialysis are focusing their attention on the use of heparin, a drug used to reduce clotting of the blood.   view more (2005-08-18)

New treatment for severe malaria
The most dangerous form of malaria is difficult to treat and claims two million lives a year. Now, researchers at Karolinska Institutet in Sweden have developed a powerful new weapon against the disease.   view more (2006-10-02)

Drug could change the standard treatment during procedures to clear blocked arteries
A study led by a University of Kentucky researcher being published in the country's leading medical journal could one day change the standard treatment for preventing blood clots during procedures to open up blocked arteries feeding the heart.   view more (2006-09-11)

Findings released from 1 of the largest percutaneous coronary intervention trials ever
A study led by Gregg W. Stone, M.D., professor of medicine at Columbia University Medical Center/NewYork-Presbyterian and chairman of the Cardiovascular Research Foundation, has shown that heart attack patients who were administered the direct thrombin inhibitor bivalirudin during primary... view more (2008-05-27)

MIT-led teams unravel heparin death mystery
An international team of researchers led by MIT has explained how contaminated batches of the blood-thinner heparin were able to slip past traditional safety screens and kill dozens of patients recently in the United States and Germany.   view more (2008-04-24)

Mass spectrometry methods database gets major update
Researchers at the National Institute of Standards and Technology (NIST) recently added 150 new methods-nicknamed "recipes"-to a database already containing 255 procedures for analyzing specific synthetic polymers using matrix-assisted laser desorption/ionization (MALDI) mass spectrometry.   view more (2006-05-26)

Oregano oil works as well as synthetic insecticides to tackle common beetle pest
New research in the Society of Chemical Industry's Journal of the Science of Food and Agriculture shows that oregano oil works as well as synthetic insecticides to combat infestation by a common beetle, Rhizoppertha dominica, found in stored cereals.   view more (2008-05-22)

Commencement 2008: Undergrad Has Sweet Success With Invention of Artificial Golgi
An undergraduate student at Rensselaer Polytechnic Institute has learned very quickly that a spoonful of sugar really does help the medicine go down. In fact, with his invention, the sugar may actually be the medicine.   view more (2008-05-08)

tudies assess blood clot prevalence outside hospital, prevention in hospital
More cases of venous thromboembolism are diagnosed in the three months following hospitalization than during hospitalization, but less than half of inpatients receive medications to prevent blood clots from occurring.   view more (2007-07-24)

Different anticoagulant regimens yield equal results
Patients with acute coronary syndromes (ACS) receiving early invasive treatment including angiography and percutaneous coronary intervention (PCI) have comparable results at 1 year in terms of mortality and ischemic outcomes no matter which of three different anticoagulant regimens they are on.   view more (2007-12-05)

Diamond detectors - The Physics Congress 2002
Diamond has an extremely high resilience to radiation - three orders of magnitude higher than silicon - making it an ideal material for detectors that monitor radioactive emissions inside the hostile environments found in nuclear energy plants. But because of the high price of real diamond,... view more (2002-04-02)

Researchers Find Synthetic Molecules That May Literally Be The Key To “Locking Away” Unwanted DNA
Research chemists have a found a class of synthetic molecules that could quite literally act as a key which could lock away sections of DNA into a closely wound coil preventing proteins from interacting with particular sections of DNA code. By locking up the DNA in this way scientists could stop... view more (2002-04-15)
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