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Donor T cells change the fate of stem cells in transplantation
When a transplant patient suffers complications such as graft rejection or graft-versus-host disease, physicians attempt to stop the body's immune response by targeting a patient's T cells.   view more (2006-07-13)

Cellular antacids give vaccines a boost
Scientists in Italy have found that a drug that blocks acid buildup inside cells revs up the immune response to vaccines.   view more (2005-09-12)

Drawing a crowd: How progenitor cells are recruited to tumor blood vessels from the bone marrow
Cells within the bone marrow (progenitor cells) that express a protein called CD34 have been shown to leave the marrow and travel to sites of tissue injury to mediate repair.   view more (2006-02-24)

Combination therapy with a monocloncal antibody and a vaccine leads to tumor rejection
Effector T cells (Teff cells) are involved in activating and directing other immune cells, while regulatory T cells (Tregs) act to curb the over-aggressive responses of the T cell population.   view more (2006-06-16)

A step forward in stem cell research
According to research published today, investigators from Memorial Sloan-Kettering Cancer Center (MSKCC) have used new techniques in the laboratory that allowed them for the first time to derive unlimited numbers of purified mesenchymal precursor cells from human embryonic stem cells (HESCs).   view more (2005-06-27)

U of MN researchers use human embryonic stem cells to kill cancer cells
For the first time, stem cell researchers at the University of Minnesota have coaxed human embryonic stem cells to create cancer-killing cells in the laboratory, paving the way for future treatments for various types of cancers (or tumors).   view more (2005-10-12)

When is a stem cell not really a stem cell?
Working with embryonic mouse brains, a team of Johns Hopkins scientists seems to have discovered an almost-too-easy way to distinguish between "true" neural stem cells and similar, but less potent versions.   view more (2007-08-27)

Early signs that adult bone-marrow stem cells could regenerate brain tissue (p 1432)
Findings of a preliminary study in this week's issue of THE LANCET suggest that transplanted adult bone-marrow cells could regenerate nerve cells in the brains of human stem-cell recipients. These early findings, if confirmed in future research, have implications for the treatment of... view more (2004-04-28)

Modified bone marrow cells can help recovery in an animal model of multiple sclerosis
A new study published in PLoS Medicine has shown that modified bone marrow cells can help recovery in an animal model of multiple sclerosis (MS).   view more (2007-04-10)

Scientists make first step towards growing human lungs for transplant
Scientists have successfully converted human embryonic stem cells into lung cells, taking a first step towards building human lungs for transplantation.   view more (2005-08-23)

Treating male infertility with stem cells
New research has examined the usefulness of bone marrow stem cells for treating male infertility, with promising results. The related report by Lue et al, "Fate of bone marrow stem cells transplanted into the testis: potential implication for men with testicular failure," appears in the... view more (2007-03-02)

Cancer cells lose drug resistance following electrical stimulation in vitro
Drug-resistant tumour cells lose their drug resistance when exposed to low intensity, low frequency electric pulses for three days.   view more (2006-03-17)

Stem cell identity in culture may strongly depend on the cellular microenvironment
Identification, isolation and large scale culture of stem cells for potential medical applications is a major challenge in cell biology.   view more (2007-04-25)

Signaling for cartilage
Skeletal progenitor cells differentiate into cartilage cells when one master gene actually suppresses the action of another, said Baylor College of Medicine researchers in a report that appears online in the journal Proceedings of the National Academy of Sciences.   view more (2006-11-28)

Dampened hopes for transplanting bone marrow stem cells in heart attacks
There is little, if any, evidence that adult stem cells can build other cells in an adult organism than those formed in the organs they themselves come from. At any rate, blood stem cells do not convert to heart muscle cells in a damaged heart, which was previously hoped. This has been shown by a... view more (2004-05-06)

FURTHER STEPS TOWARDS A VACCINE AGAINST HIV
For white blood cells in the human body to be infected by the HIV virus, proteins in the virus must be allowed to interact with a number of different components on the surface of the white blood cell. Ideally anti-HIV preventive therapy or vaccines would prevent several of these interactions taking... view more (1999-03-11)

Scientists find stem cell switch
Scientists have discovered how plant stem cells in roots detect soil structure and whether it is favourable for growth.   view more (2007-07-27)

Cancer stem cells similar to normal stem cells can thwart anti-cancer agents
Current cancer therapies often succeed at initially eliminating the bulk of the disease, including all rapidly proliferating cells, but are eventually thwarted because they cannot eliminate a small reservoir of multiple-drug-resistant tumor cells, called cancer stem cells, which ultimately become... view more (2007-06-18)

New cell culturing method pumps up the volume
In a breakthrough that will likely accelerate research aimed at cures for hearing loss, tinnitus, and balance problems, scientists have perfected a laboratory culturing technique that provides a reliable new source of cells critical to understanding certain inner-ear disorders.   view more (2007-09-25)

Stem cells as cancer therapy
It is widely hoped that neural stem cells will eventually be useful for replacing nerves damaged by degenerative diseases like Alzheimer disease and multiple sclerosis. But there may also be another use for such stem cells-delivering anti-cancer drugs to cancer cells.   view more (2006-12-26)

'Killer' B cells provide new link in the evolution of immunity
Researchers from the University of Pennsylvania School of Veterinary Medicine have discovered a unique evolutionary link between the most primitive innate form of immune defense, which has survived in fish, to the more advanced, adaptive immune response present in humans and other mammals.   view more (2006-10-04)

Dictyostelium cells shown to lay 'breadcrumb trail' as first step in multicellular formation
When starved of their food source and then presented with a chemoattractant signal like cAMP, individual Dictyostelium cells acquire a polarized morphology and aggregate to form a migrating stream.   view more (2008-12-01)

CHECKING HOW CELLS GROW: New research dismisses a widely held assumption about cell growth
Research published today in Journal of Biology challenges an assumption about cell growth that underpins modern cellular biology. Ian Conlon and Martin Raff, of University College London, show that mammalian cells do not regulate their size in the way scientists have assumed they do since the... view more (2003-04-23)

New brain cells listen before they talk
Newly created neurons in adults rely on signals from distant brain regions to regulate their maturation and survival before they can communicate with existing neighboring cells-a finding that has important implications for the use of adult neural stem cells to replace brain cells lost by trauma or... view more (2007-10-31)

Malaria parasite impairs key immune system cells
Plasmodium, the parasite responsible for malaria, impairs the ability of key cells of the immune system to trigger an efficient immune response.   view more (2006-04-12)
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