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Light powered platinum more targeted & 80 times more powerful than similar cancer treatments
Researchers from the Universities of Warwick, Edinburgh, Dundee and the Czech Republic's Institute of Biophysics have discovered a new light-activated platinum-based compound that is up to 80 times more powerful than other platinum-based anti-cancer drugs and which can use "light... view more (2007-12-26)

Researchers aim to cut future need for liver transplants
University of Edinburgh scientists have identified primitive liver cells —possibly dormant from the earliest developmental stage of a human being — which have the potential to mature into different cells types and help repair a failing liver.   view more (2006-07-07)

UCLA researchers develop T-cells from human embryonic stem cells
Researchers from the UCLA AIDS Institute and the Institute for Stem Cell Biology and Medicine have demonstrated for the first time that human embryonic stem cells can be genetically manipulated and coaxed to develop into mature T-cells, raising hopes for a gene therapy to combat AIDS.   view more (2006-07-05)

When smell cells fail they call in stem cell reserves
Hopkins researchers have identified a backup supply of stem cells that can repair the most severe damage to the nerves responsible for our sense of smell.   view more (2007-04-30)

Parasite lipids against asthma or diabetes
Dutch research has demonstrated that lipids from the parasite schistosoma can inhibit human immune responses. This property makes the lipids interesting for a possible new treatment of diseases such as asthma and diabetes where the immune system responds inappropriately. During her doctoral... view more (2003-11-11)

How insulin-producing cells develop -- new finding could help fight against diabetes
A key aspect of how embryos create the cells which secrete insulin is revealed in a new study published tomorrow (18 May) in the Journal of Biological Chemistry.   view more (2007-05-18)

Enzyme promotes fat formation
The enzyme TPPII may contribute to obesity by stimulating the formation of fat cells, suggests a study in EMBO reports this week. The enzyme, TPPII, has previously been linked to making people feel hungry, but Jonathan Graff and colleagues now show that it may be even more deeply involved in... view more (2007-10-12)

Healthy blood vessels may prevent fat growth
The cells lining blood vessels are known to be important for maintaining health, but researchers at the Indiana University School of Medicine believe these cells may perform an unsuspected task - controlling the development of fat cells.   view more (2008-09-22)

Inflammation kills new brain cells
A research team at Lund University in Sweden attracted international attention a year ago by showing that new nerve cells can be generated in the brain after a stroke. However, most of these new nerve cells die rather soon. The same research team has now been able to show that an inflammation can... view more (2003-11-10)

Human stem cell transplants mature into neurons and make contacts in rat spinal cord
Human nerve stem cells transplanted into rats' damaged spinal cords have survived, grown and in some cases connected with the rats' own spinal cord cells in a Johns Hopkins laboratory, overturning the long-held notion that spinal cords won't allow nerve repair.   view more (2007-02-14)

Blood vessel cells are instructed to form tube-like structures
How do blood vessel cells understand that they should organise themselves in tubes and not in layers? A research group from Uppsala University shows for the first time that a special type of "instructor" molecule is needed to accomplish this. These findings, published in the scientific... view more (2008-08-29)

New U of T strategy will boost cord blood stem cells
A team of bioengineers led by the University of Toronto has discovered a way to increase the yield of stem cells from umbilical cord blood, to an extent which could broaden therapeutic use of these cells.   view more (2005-10-19)

Studying component parts of living cells with carbon nanotube cellular probes
Carbon nanotubes (CNTs) have shown great potential for use as cellular probes. As "nanopipes" they can be used to transport liquids to or from cells and inject solutions or drugs directly into individual cells and individual organelles within the cells.   view more (2007-10-05)

US funding for Lund research for project on adult stem cells
Adult stem cells are to be treated so that they develop characteristics of nerve cells and can produce dopamine, according to Associate Professor Jia-Yi Li at the Wallenberg Neuro Center at Lund University, who has received a grant of some SEK 2 million from the National Institutes of Health (NIH),... view more (2003-01-29)

Tumor cells evade death through autophagy
Autophagy is a cellular process that enables cells to turnover their contents, something that they do frequently. Autophagy is initiated in tumor cells by chemotherapy and radiation, but it is not known if this contributes to tumor cell death or helps tumor cells survive the anti-cancer therapy.   view more (2007-01-19)

Dual functions of gene revealed, for better and for worse
Researchers at WEHI have pinpointed the function of a potent cancer gene. The gene, known as "ERG", has long been associated with a range of human malignancies, including leukemia and sarcoma. American scientists showed in 2005 that ERG is mutated in more than half of all prostate... view more (2008-05-27)

Geisinger study: Inflammatory disease causes blindness
People suffering from a type of connective tissue disease characterized by inflammation of arteries in the head are three times more likely to experience blindness, new Geisinger research shows.   view more (2008-06-17)

Tracking the spread of cancer cells - Photon02
Not much is known about how clustered cancer cells move, but it is important to understand how individual cancer cells break off from a cluster and spread throughout the human body. A research collaboration between the University of Wales College of Medicine and Kingston University * has lead to... view more (2002-08-28)

Cellular self-eating promotes pancreatitis
To survive tough times, cells sometimes resort to a form of self-cannibalism called autophagy. But as Hashimoto et al. reveal, autophagy can have a down side, destroying the pancreas by prematurely activating a digestive enzyme.    view more (2008-06-30)

Isolation of a new gene family essential for early development
Researchers at BRIC, University of Copenhagen, have identified a new gene family (UTX-JMJD3) essential for embryonic development. The family controls the expression of genes crucial for stem cell maintenance and differentiation, and the results may contribute sig-nificantly to the understanding of... view more (2007-08-23)

USC researchers discover breast cancer stem cells in bone marrow
Almost all tumor cells found in the bone marrow of early stage breast cancer patients appear to be breast cancer stem cells, suggesting the risk of disease spread for all breast cancer patients may be greater than previously thought.   view more (2006-10-09)

Mobilizing white blood cells to the lung: New discovery could lead to an improved influenza vaccine
Findings just published in the scientific journal Immunity by researchers at the Trudeau Institute shed new light on how a previously-unknown messaging mechanism within the human immune system prompts specific influenza-fighting cells to the lung airways during an infection.   view more (2008-07-11)

Scientists in Japan design first optical pacemaker for laboratory research
The world's first optical pacemaker is described in an article published today in Optics Express, the Optical Society's open-access journal. A team of scientists at Osaka University in Japan show that powerful, but very short, laser pulses can help control the beating of heart muscle cells.   view more (2008-05-28)

Why is Apert's syndrome so common when mutation rate is so low?
Aperts syndrome is a condition caused by a mutation that produces fused fingers and toes, and alters cranial development in affected children.   view more (2007-08-28)

Gene therapy protocol at UCSD activates immune system in patients with leukemia
A research team at the Moores Cancer Center at University of California, San Diego (UCSD) reports that patients with chronic lymphocytic leukemia (CLL) who were treated with a gene therapy protocol began making antibodies that reacted against their own leukemia cells.   view more (2008-02-12)
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