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Stem-cell therapy could have benefits and risks for heart-attack patients (pp 746, 751, 783)
Two studies in this week's issue of THE LANCET raise questions about the feasibility and safety of stem-cell therapy for heart disease, suggesting that such treatments could have both benefits and drawbacks. Adult haemopoietic stem cells give rise to blood cells, and are thought to be able to... view more (2004-03-03)

Fight against hay fever and other allergies helped by new immune system discovery
A mechanism which can lead to hay fever and other allergic reactions, by preventing the immune system from regulating itself properly, has been discovered by scientists.   view more (2007-12-27)

Rat kidneys and toad brains communicate in almost the same manner
Dutch researcher Niels Cornelisse used computer models to study the electrochemical communication between cells from rat kidneys and cells from the pituitary gland of a toad species. He found many similarities in the coupling of chemical and electrical signals in these completely different cells.   view more (2004-05-07)

Human beta-cell line offers hope for type 1 diabetes breakthrough
Transplantation of insulin-producing pancreatic beta-cells shows great promise as a treatment for type 1 diabetes, but development of this therapy has been hampered by a severe shortage of donor beta-cells, which are obtained from decreased human donors.   view more (2005-09-27)

The immune system and Alzheimer's disease
Utrecht researchers, funded by NWO, have determined the role played by brain cells from the immune system that are located close to dying memory cells. The research will help determine the causes of Alzheimer's disease. In patients with Alzheimer's disease, the brain cells die off. The death of... view more (2001-11-27)

UCLA stem cell researchers create heart and blood cells from reprogrammed skin cells
Stem cell researchers at UCLA were able to grow functioning cardiac cells using mouse skin cells that had been reprogrammed into cells with the same unlimited properties as embryonic stem cells.   view more (2008-04-30)

'Allergy cells' can aggravate cancer and psoriasis
The body's mast cells are mainly associated with allergic reaction in the way they release histamine and other inflammatory substances.   view more (2006-09-11)

New treatment for severe malaria
The most dangerous form of malaria is difficult to treat and claims two million lives a year. Now, researchers at Karolinska Institutet in Sweden have developed a powerful new weapon against the disease.   view more (2006-10-02)

Therapeutic cloning treats Parkinson's disease in mice
Research led by investigators at Memorial Sloan-Kettering Cancer Center (MSKCC) has shown that therapeutic cloning, also known as somatic-cell nuclear transfer (SCNT), can be used to treat Parkinson's disease in mice. The study's results are published in the March 23 online edition of the journal... view more (2008-03-24)

Marijuana-like compounds suppress the immune response
A group of Japanese scientists has discovered that cannabinoids can cause some white blood cells to lose their ability to migrate to the sites of infection and inflammation.   view more (2006-04-27)

Hemangioma arteriovenous malformations or how endothelial cells escape apoptosis (programmed cell death).
Hemangiomas included several types of vascular abnormalities. The first classification of vascular abnormalities was proposed in 1982. Since angiography is becoming a common investigation, a better identification of the vascular abnormalities was possible. Hemangiomas are frequent in children and... view more (1999-09-14)

ESC Congress 2003: Stem cell therapy for myocardial repair & regeneration
IMPORTANT: This press release accompanies both a presentation and an ESC press conference given at the ESC Congress 2003. Written by the investigator himself/herself, this press release does not necessarily reflect the opinion of the European Society of Cardiology Heart attack and the resulting... view more (2003-09-01)

Metastatic movements in 3-D
Caswell et al.report in the Journal of Cell Biology how the altered behavior of integrins can prompt metastatic movement in tumor cells.    view more (2008-10-06)

U of MN research shows how infection-fighting cells interact
Researchers at the University of Minnesota have identified key insights into how different types of infection-fighting T-cells survive and co-exist within the body's immune system.   view more (2006-03-06)

A potential route for human tumor gene therapy
The type 1 Na+/H+ exchanger (NHE1) is a transmembrane protein found in all eukaryotic cells. One of its functions is to evacuate excessive H+ in the cytoplasm by means of Na+-H+ exchange, resulting in stable intracellular pH value.   view more (2008-05-21)

Regulatory T cells require WASp if they are to prevent self-destruction
In humans, mutation of the gene encoding a protein known as WASp leads to susceptibility to infections and systemic autoimmunity.   view more (2007-01-12)

Epilepsy and brain pathology linked together by the protein ADK
The brain of individuals who suffer from epilepsy is characterized by astrogliosis, a brain pathology evidenced by a complex series of changes in the morphology and function of brain cells known as astrocytes.   view more (2008-01-03)

Researchers identify genes that allow brain cancer-causing stem cells to resist treatment
While great interest has followed the discovery of neural stem cells and their potential for someday treating diseases and injuries of the brain and spinal cord, recent research identified "cancer stem cells," a small population of cells that appear to be the source of cells comprising a... view more (2006-12-18)

A potential sugar fix for tumors
Researchers at the Duke School of Medicine apparently have solved the riddle of why cancer cells like sugar so much, and it may be a mechanism that could lead to better cancer treatments.   view more (2008-04-16)

Loss of nerve cells may link constipation with achalasia of the oesophagus
Patients who have difficulty swallowing food may also be more likely to suffer from constipation, according to a preliminary study published this week in BMC Gastroenterology. The research suggests that patients with achalasia of the oesophagus, associated with a loss of nerve cells in the muscle... view more (2003-10-13)

Burnham Researchers Turn Cancer Friend into Cancer Foe
Burnham Institute for Medical Research today announced that scientists have created a peptide that binds to Bcl-2, a protein that protects cancer cells from programmed cell death, and converts it into a cancer cell killer.   view more (2008-10-08)

Penn Scientists Show How Body Determines Optimal Amount of Germ-Fighting B Cells
Researchers at the University of Pennsylvania School of Medicine can now explain how the body determines whether there are enough mature B-cells in the blood stream at any one time. These are the cells that produce antibodies against germs to fight infections.   view more (2008-11-05)

Discovery of new signal pathway important to diabetes research
Scientists at Karolinska Institutet in Sweden and Miami University have discovered that cells in the pancreas cooperate - signal - in a way hitherto unknown. The discovery can eventually be of significance to the treatment of diabetes.   view more (2008-06-05)

Cell research signals cancer hope
Scientists have moved a step closer to understanding what happens when cells receive a faulty signal that is known to be a cause of cancer.   view more (2005-02-03)

Researchers reveal repressor protein blocks neural stem cell development
A protein known to repress gene transcription at the molecular level in a variety of processes also blocks embryonic neural stem cells from differentiating into neurons.   view more (2007-10-11)
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