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New evidence eases some concerns about bone fracture risk with breast cancer drug
Copenhagen, Denmark: New evidence about the breast cancer drug anastrozole (Arimidex) shows that the incidence of a major side-effect - bone fractures - appears to stabilise after reaching a peak at two years of treatment, easing some of the concerns about the drug. This finding is the latest to come from evidence provided by the world's largest... view more... (2003-09-21)

Exemestane beats tamoxifen in first phase III head to head trial in advanced breast cancer
Hamburg, Germany: The first results from the world's only phase III trial to compare tamoxifen with the newer hormone treatment exemestane in advanced breast cancer shows that exemestane is safe, superior and lengthens progression-free survival. The median progression-free survival for patients taking exemestane was 10.9 months compared with 6.7... view more... (2004-03-16)

Study of adjuvant endocrine treatment for breast cancer reveals cost of noncompliance
The largest study in the world of treatments for post menopausal, hormone positive breast cancer has shown that patients who continue to take exemestane or tamoxifen do significantly better than patients who start to take one or other drug (or tamoxifen followed exemestane) but then stop.   view more (2009-09-22)

Benefit of chemotherapy in breast cancer depends on estrogen-receptor status
When it comes to chemotherapy treatment for women whose breast cancer has spread to their lymph nodes, the estrogen status of their tumors matters.   view more (2006-04-12)

Meta-analyses of global trials finds in favor of aromatase inhibitors
Two separate meta-analyses of clinical trials from around the world that tested tamoxifen against aromatase inhibitor drugs in postmenopausal women with early breast cancer have each reached the same conclusion: aromatase inhibitors are more effective in preventing breast cancer from coming back.   view more (2008-12-12)

New role for tamoxifen as fertility drug for breast cancer patients?
US fertility experts have discovered a potential new role for the wonder drug tamoxifen - helping breast cancer patients to have babies by IVF. In a study published today (Wednesday 8 January) in Europe's leading reproductive medicine journal Human Reproduction [1], researchers from New York's Cornell University report the first IVF pregnancy to... view more... (2003-01-03)

Manic phase of bipolar disorder benefits from breast cancer medication
The medication tamoxifen, best known as a treatment for breast cancer, dramatically reduces symptoms of the manic phase of bipolar disorder more quickly than many standard medications for the mental illness, a new study shows.   view more (2007-09-12)

VBI researchers develop new method for breast cancer biomarker discovery
Three researchers from the Virginia Bioinformatics Institute (VBI) at Virginia Tech have developed and evaluated a new one-step bioanalytical approach that allows them to profile in detail complex cellular extracts of proteins.   view more (2009-06-10)

Acupuncture relieves hot flushes in breast cancer patients taking tamoxifen
Acupuncture provides effective relief from hot flushes in women who are being treated with the anti-oestrogen tamoxifen following surgery for breast cancer, according to new research presented today (Friday) at the 6th European Breast Cancer Conference (EBCC-6) in Berlin.   view more (2008-04-18)

Hormone drug type makes survival difference in advanced breast cancer
Aromatase inhibitors, a type of hormone therapy used to treat advanced breast cancer in postmenopausal women, result in a small but significant increase in overall survival when compared to other hormone treatments, according to a new systematic review of studies.   view more (2007-01-31)

Leading cancer doctor calls for new guidelines to control early reporting from clinical trials
Hamburg, Germany: A leading breast cancer doctor is urging researchers to consider changing the guidelines that govern whether clinical trials should be stopped prematurely, as she believes that current practice could be damaging research efforts. Dr Martine Piccart, head of the chemotherapy unit at the Institut Jules Bordet, Brussels, Belgium, is... view more... (2004-03-16)

Researchers say estrogen can kill breast cancer cells once fueled by the hormone
Fox Chase Cancer Center researchers say some breast cancer cells once fueled by estrogen can be killed by the same hormone.   view more (2005-12-07)

Serendipity versus planning-cancer drugs of the future?
Delegates at the European Breast Cancer Conference (EBCC-5) were given two examples of promising new drugs to watch in the future-raloxifene and lapatinib.   view more (2006-03-27)

Weekly dose of osteoporosis drug prevents bone loss after breast cancer treatment
Breast cancer survivors who took a weekly dose of risedronate, sold as Actonel, lost significantly less bone than those who did not take the drug.   view more (2007-09-19)

Previously unseen switch regulates breast cancer response to estrogen
A tiny modification called methylation on estrogen receptors prolongs the life of these growth-driving molecules in breast cancer cells, according to research by scientists at Emory University's Winship Cancer Institute.   view more (2008-05-09)

Researchers zero in on estrogen's role in breast-cancer cell growth
Why do estrogen-dependent breast-cancer cells grow and spread rapidly? Researchers at the University of Illinois at Urbana-Champaign say it may be because estrogen virtually eliminates levels of a vitally important regulatory protein.   view more (2005-09-12)

13 percent of women stop taking breast cancer drug because of side effects, U-M study finds
More than 10 percent of women with breast cancer stopped taking a commonly prescribed drug because of joint and muscle pain, according to a new study from researchers at the University of Michigan Comprehensive Cancer Center.   view more (2007-09-06)

LA BioMed research finds simpler way to assess breast cancer risk
A new, simpler model for predicting breast cancer risk in postmenopausal women appears to be as accurate as a more complicated method currently used to decide if women would benefit from medication to reduce their risk of getting cancer, according to research published today in the Journal of the National Cancer Institute.   view more (2007-11-14)

Medications Effective in Reducing Risks for Breast Cancer Can Also Cause Serious Side Effects
Three drugs that reduce a woman's chance of getting breast cancer also have been shown to cause adverse effects, according to a new report from the Agency for Healthcare Research and Quality (AHRQ), U.S. Department of Health & Human Services.   view more (2009-09-21)

Estrogen-Dependent Switch Tempers Killing Activity of Immune Cells
The sex hormone estrogen tempers the killing activity of a specific group of immune cells, the cytotoxic T cells (CTLs), which are known to attack tumor cells and cells infected by viruses.   view more (2009-08-10)
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