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Tamoxifen Current Events | Tamoxifen News | 2
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Researchers say estrogen can kill breast cancer cells once fueled by the hormone
Fox Chase Cancer Center researchers say some breast cancer cells once fueled by estrogen can be killed by the same hormone. view more (2005-12-07)
Serendipity versus planning-cancer drugs of the future?
Delegates at the European Breast Cancer Conference (EBCC-5) were given two examples of promising new drugs to watch in the future-raloxifene and lapatinib. view more (2006-03-27)
Weekly dose of osteoporosis drug prevents bone loss after breast cancer treatment
Breast cancer survivors who took a weekly dose of risedronate, sold as Actonel, lost significantly less bone than those who did not take the drug. view more (2007-09-19)
Previously unseen switch regulates breast cancer response to estrogen
A tiny modification called methylation on estrogen receptors prolongs the life of these growth-driving molecules in breast cancer cells, according to research by scientists at Emory University's Winship Cancer Institute. view more (2008-05-09)
Researchers zero in on estrogen's role in breast-cancer cell growth
Why do estrogen-dependent breast-cancer cells grow and spread rapidly? Researchers at the University of Illinois at Urbana-Champaign say it may be because estrogen virtually eliminates levels of a vitally important regulatory protein. view more (2005-09-12)
13 percent of women stop taking breast cancer drug because of side effects, U-M study finds
More than 10 percent of women with breast cancer stopped taking a commonly prescribed drug because of joint and muscle pain, according to a new study from researchers at the University of Michigan Comprehensive Cancer Center. view more (2007-09-06)
LA BioMed research finds simpler way to assess breast cancer risk
A new, simpler model for predicting breast cancer risk in postmenopausal women appears to be as accurate as a more complicated method currently used to decide if women would benefit from medication to reduce their risk of getting cancer, according to research published today in the Journal of the... view more (2007-11-14)
New study reveals big disparity between countries in breast conservation rates
Hamburg, Germany: The rates of conservation surgery for breast cancer vary hugely between countries, delegates at the 4th European Breast Cancer Conference heard today (Friday 19 March). In France 72% of patients had breast conservation surgery but in Poland it was only 2%. The figures come from an... view more (2004-03-17)
Study uncovers significant functional differences of novel estrogen receptor
Because of these differences, this new estrogen receptor could become an important therapeutic target and may play a further signaling role in other estrogen target tissues, including uterus and prostate tissues. view more (2006-06-09)
Newer chemotherapies improve outcomes for some types of breast cancer
An updated analysis of findings from three major consecutive clinical trials of breast cancer treatment conducted over the past twenty years indicates that women who have breast cancer with lymph node involvement and estrogen-receptor negative tumors have a lower rate of recurrence and risk of... view more (2006-04-12)
Benefits Outweigh Burden Of Chemotherapy After Breast Cancer (P 277)
The benefits of adjuvant chemotherapy for breast cancer outweigh its side-effects, especially for younger women, conclude authors of a study in this week's issue of THE LANCET. Previous randomised trials have shown that prolonged chemotherapy for breast cancer substantially reduces the risk of... view more (2001-07-25)
New test can identify patients who may suffer serious late toxicity from radiotherapy
Radiotherapists in Switzerland have developed a fast test that can be used immediately on patients to discover whether they are likely to suffer serious late onset side effects from radiation. view more (2003-09-20)
High levels of estrogen associated with breast cancer recurrence
Women whose breast cancer came back after treatment had almost twice as much estrogen in their blood than did women who remained cancer-free - despite treatment with anti-estrogen drugs in a majority of the women -according to researchers in a study published in the March issue of Cancer... view more (2008-03-06)
Mayo Clinic study finds two genes predict outcome for breast cancer patients
The 2-gene expression profile of HOXB13 and IL17BR in a woman's breast cancer predicts risk of recurrence in node-negative patients treated with tamoxifen. view more (2006-04-03)
Drug developed at UC Davis may prevent breast cancer, treat post-menopausal vaginal atrophy
A tamoxifen-like drug developed by UC Davis and Finnish researchers, now in clinical testing as a treatment for vaginal atrophy, may also help to prevent breast cancer, two preliminary studies suggest. view more (2005-11-03)
Whites take supplemental breast cancer therapy more often than blacks
A new study finds that white women more frequently take more of the life-prolonging supplemental therapies used to treat breast cancer than African-American women. view more (2007-10-08)
Cancer Researchers at the University of Pennsylvania Discover What Makes Lymphomas Tick
University of Pennsylvania researchers and their colleagues at the Wistar Institute and University of Oxford have discovered the molecular process by which the PAX5 protein, necessary for lymphocyte development, promotes the growth of common lymphomas, thereby unveiling a potential new target in... view more (2007-08-30)
Scientists find a way to detect which breast abnormalities may develop into cancer
Scientists at the Royal Liverpool University Hospitals in the UK have found a way of testing whether certain abnormalities in a woman's breast are likely to go on to develop into breast cancer, the 3rd European Breast Cancer Conference in Barcelona heard today (Wednesday 20 March). Armed with... view more (2002-03-18)
The Lancet Oncology
CLEAR SKIES NOT SO CLEAN This months Leading Edge editorial examines the recently published US Environmental Protection Agency`s (EPA) 10-year in-the-making report on the toxic effects of diesel exhaust fumes from large vehicles. The report-which showed that large cities are heavily polluted with... view more (2002-10-02)
Risk assessment plays key role in long-term treatment of breast cancer
Breast cancer patients and their physicians may make more informed, long-term treatment decisions using risk assessment strategies to help determine probability of recurrence. view more (2008-08-13)
Young Breast Cancer Patients Who Chose Lumpectomies Should Have Indefinite Follow-Up Because Of Late Recurrence Risk
Young breast cancer patients who have breast conserving treatment are at higher risk of recurrence many years later than are older women who have the same treatment or women who have mastectomies, according to research published (Monday 3 November) in Annals of Oncology.[1] The researchers are... view more (2003-10-31)
Hamilton College Researchers Discover New Molecules with the Potential to Treat Breast Cancer
Hamilton College researchers have identified molecules that have been shown to be effective in the fight against breast cancer. view more (2007-05-07)
Linchpin gene may be useful target for new breast cancer therapies
University of Iowa researchers have discovered a gene that plays a linchpin role in the ability of breast cancer cells to respond to estrogen. The finding may lead to improved therapies for hormone-responsive breast cancers and may explain differences in the effectiveness of current treatments. view more (2007-09-17)
New Cause of Tamoxifen Resistance in Breast Cancer Cells Discovered at Lombardi
When a woman receives a breast cancer diagnosis her entire life may change in the blink of an eye. But the nature of that change is governed by the smallest alterations that take place within the proteins of the tumor cells, determining what treatments she can pursue with a hope of cure and those... view more (2007-08-13)
New computational technique can predict drug side effects
Early identification of adverse effects of drugs before they are tested in humans is crucial in developing new therapeutics, as unexpected effects account for a third of all drug failures during the development process. view more (2007-12-12)
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