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Tamoxifen Current Events | Tamoxifen News | 4

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New Cause of Tamoxifen Resistance in Breast Cancer Cells Discovered at Lombardi
When a woman receives a breast cancer diagnosis her entire life may change in the blink of an eye. But the nature of that change is governed by the smallest alterations that take place within the proteins of the tumor cells, determining what treatments she can pursue with a hope of cure and those to which her cancer is resistant.   view more (2007-08-13)

Women with BRCA mutation, or worry, most likely to undergo prophylactic mastectomy
Women at increased risk for breast cancer because of the genetic BRCA mutations are more likely to think a prophylactic mastectomy is the best way to reduce their risk for the disease, compared to other women who are at high risk, according to researchers at The University of Texas M. D. Anderson Cancer Center.   view more (2009-03-09)

New computational technique can predict drug side effects
Early identification of adverse effects of drugs before they are tested in humans is crucial in developing new therapeutics, as unexpected effects account for a third of all drug failures during the development process.   view more (2007-12-12)

US researchers show cottonseed drug is cancer treatment booster - patient trials now planned
New research has opened up the prospect that gossypol - a drug refined from cottonseed oil and previously tried and abandoned as a male contraceptive - could boost the effectiveness of treatment for prostate tumours and possibly other common cancers as well.   view more (2004-09-29)

Women with breast cancer do not get potentially life-saving information, survey reveals
New published data from a large pan-European survey indicate that the majority of postmenopausal women with early breast cancer taking post-surgical endocrine therapy are not involved in making key decisions about their treatment, nor are they given sufficient information to make informed treatment choices that could affect their long-term outcome.   view more (2007-05-24)

Mayo Clinic researchers say agent provides treatment option for women with hot flashes
A pill used for nerve pain offers women relief from hot flashes, Mayo Clinic researchers report at the 45th Annual Meeting of the American Society of Clinical Oncology (ASCO).   view more (2009-05-15)

Older people lose out all round in breast cancer treatment and care
Hamburg, Germany: Managing breast cancer in elderly patients presents particularly difficult challenges, a scientist said today (Thursday March 18) at the 4th European Breast Cancer Conference.   Professor Lars Holmberg, from the Regional Oncologic Centre, Uppsala, Sweden, said that, with about 25% of all breast cancer patients... view more... (2004-03-16)

New 'Knock-Out' Gene Model Provides Molecular Clues to Breast Cancer
New insights into the role of estrogen receptor in mammary gland development may help scientists better understand the molecular origin of breast cancer, according to new research from the University of Cincinnati (UC).   view more (2007-09-06)

New Clues to Breast Cancer Development in High-Risk Women
Physicians who treat women with the breast cancer susceptibility gene BRCA1 often remove their patients' ovaries to eliminate the source of estrogen they believe fuels cancer growth.   view more (2007-09-12)

New hormone research presented at BES annual meeting
BRITISH ENDOCRINE SOCIETIES ANNUAL MEETING: HARROGATE 8-11 APRIL The British Endocrine Societies (BES) meeting is Europe’s largest annual meeting of hormone specialists. Over 400 papers will present new research from Britain and around the world, including: ·       Why does smoking cause cancer? Possible new... view more... (2002-04-03)

Aromatase inhibitors: A treatment of choice for advanced breast cancer patients
Aromatase inhibitors improve the survival of advanced breast cancer patients compared to standard hormone therapies like tamoxifen.   view more (2006-09-20)

Breast cancer prevention practices vary across Canada
Breast cancer preventive practices for Canadian women carrying the cancer gene vary across the country, says University of Toronto research, and many women are not taking advantage of the options available.   view more (2007-08-15)

A new computational technique predicts side-effects of a major cancer drug
Researchers at the University of California San Diego have developed a novel computer technique to search for the side effects of major pharmaceuticals.   view more (2007-11-28)

Concern Over Poor UK Recruitment To Chemotherapy Trials For Women At High Risk Of Breast Cancer (pp 853, 889)
The effectiveness of prophylactic chemotherapy for women who are at a high risk of breast cancer may remain unclear unless more UK women are recruited to chemotherapy trials, conclude authors of a research letter in this week's issue of THE LANCET. Appropriate management of women at high lifetime risk of familial breast cancer is hampered because... view more... (2001-09-12)

DACH1 a key protein for tumor suppression in ER+ breast cancer
Researchers from the Kimmel Cancer Center at Jefferson have identified a protein relationship that may be an ideal treatment target for ER+ breast cancer.   view more (2009-07-15)

US prostate cancer deaths down one third in men aged 50-74: Europe following?
Copenhagen, Denmark: New findings presented today (Tuesday 23 September) at ECCO 12 - The European Cancer Conference, show that US prostate cancer mortality rates, which had been increasing slowly during the 1970s and 1980s, suddenly started to fall rapidly during the 1990s.   view more (2003-09-21)

Microarray provides 3 genomic guides to breast cancer treatment decisions
Three genomic tests separately predict the likelihood that a patient's breast cancer will reoccur after surgery without additional treatment, and the cancer's vulnerability to chemotherapy or hormone therapy.   view more (2007-09-07)

Compliance and cost: Bitter pills to swallow in the age of oral chemotherapy
Though the growing shift toward oral chemotherapy agents offers cancer patients greater freedom and independence during their treatment, physicians say use of the new medications also poses more chances for patients to skip doses, miss prescription refills, and take their drugs in a dangerous way.   view more (2009-05-29)

Breast cancer more aggressive among obese women
Women with breast cancer have more aggressive disease and lower survival rates if they are overweight or obese, according to findings published in the March 15 issue of Clinical Cancer Research, a journal of the American Association for Cancer Research.   view more (2008-03-14)

PROPHYLACTIC MASTECTOMYImperial Cancer surgeon argues for scheme to find out if removal of healthy breasts justified in women at high risk of cancer
A London surgeon, Professor Ian Fentiman of the Imperial Cancer Research Fund Breast Oncology Group, has called for the creation of a compulsory register of all women who undergo prophylactic mastectomy. Only in this way, he says, will we find out if operating to remove the breast tissue of healthy women at high risk of breast cancer really does... view more... (1998-11-18)
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