Telomeres Current Events | Telomeres News | 2
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A little telomerase isn't enough
Chromosome ends, or telomeres, are repetitive stretches of DNA that protect chromosomes in much the same way as plastic tips on shoelaces prevent the fabric from fraying. view more (2005-12-23)
Researchers use chemical from medicinal plants to fight HIV
Like other kinds of cells, immune cells lose the ability to divide as they age because a part of their chromosomes known as a telomere becomes progressively shorter with cell division. As a result, the cell changes in many ways, and its disease fighting ability is compromised. view more (2008-11-10)
UGA researchers discover mechanism that explains how cancer enzyme winds up on ends of chromosomes
Human cancer cells divide and conquer. Unless physicians can control that division with surgery, chemotherapy or radiation, the wildly dividing cells will eventually destroy a person's life. view more (2008-07-11)
Mice regain ability to extend telomeres suggesting potential for dyskeratosis congenita therapy
The human genetic disease dyskeratosis congenita (DKC) is an autosomal dominant disease that leads to abnormalities in tissues with a rapid cell turnover - the skin, nails, bone marrow, lungs and gut. view more (2009-10-19)
Oncologists could gain therapeutic advantage by targeting telomere protein
Inactivating a protein called mammalian Rad9 could make cancer cells easier to kill with ionizing radiation, according to research at Washington University School of Medicine in St. Louis. view more (2006-02-17)
Immune cells from patients with rheumatoid arthritis have prematurely aged chromosomes
Telomeres, structures that cap the ends of cells' chromosomes, grow shorter with each round of cell division unless a specialized enzyme replenishes them. Maintaining telomeres is thought to be important for healthy aging and cancer prevention. view more (2009-03-05)
First sister study results reinforce the importance of healthy living
Women who maintain a healthy weight and who have lower perceived stress may be less likely to have chromosome changes associated with aging than obese and stressed women, according to a pilot study that was part of the Sister Study. view more (2009-03-17)
Possible Link Studied Between Childhood Abuse and Early Cellular Aging
Children who suffer physical or emotional abuse may be faced with accelerated cellular aging as adults, according to new research from Butler Hospital and Brown University. view more (2009-11-23)
FISH-ing for links between cancer and aging
Wielding a palette of chromosome paints, scientists at the Salk Institute for Biological Studies have taken a step closer to understanding the relationship between aging and cancer by visualizing chromosomes of cells from patients with a heritable premature aging disease known as Werner Syndrome. view more (2007-02-06)
Investigators uncover intriguing clues to why persistent acid reflux sometimes turns into cancer
New research from scientists at UT Southwestern Medical Center and the Dallas Veterans Affairs Medical Center underscores the importance of preventing recurring acid reflux while also uncovering tantalizing clues on how typical acid reflux can turn potentially cancerous. view more (2007-08-10)
Protein plays unexpected role protecting chromosome tips
A protein specialist that opens the genomic door for DNA repair and gene expression also turns out to be a multi-tasking workhorse that protects the tips of chromosomes and dabbles in a protein-destruction complex, a team lead by researchers at The University of Texas M. D. Anderson Cancer Center reports in the Aug. 13 edition of Molecular Cell. view more (2009-08-14)
New target for cancer therapy identified
A new target for cancer therapy has been identified by Monash University scientists investigating the cell signalling pathways that turn on a gene involved in cancer development. view more (2006-09-22)
Telomerase inhibition - a cancer therapy that is not always what it seems
Telomerase is a protein involved in cancer where it is present in 85 to 90% of all cases. Taking advantage of this fact, over the last years multiple new approaches have appeared that aim to inhibit telomerase activity as a new treatment strategy in human cancer. However, in the latest issue of the journal Oncogene scientists reveal that in some... view more... (2004-05-25)
When cells go bad
When a cell's chromosomes lose their ends, the cell usually kills itself to stem the genetic damage. But University of Utah biologists discovered how those cells can evade suicide and start down the path to cancer. view more (2008-10-01)
Hotspots found for chromosome gene swapping
Crossovers and double-strand DNA breaks do not occur randomly on yeast chromosomes during meiosis, but are greatly influenced by the proximity of the chromosome's telomere, according to research in the laboratory of Whitehead Fellow Andreas Hochwagen. view more (2007-11-30)
The clue of genomic instability in breast cancer
New research has shown, using human tissue biopsies - a hypothesis that until now could only be argued indirectly using cell cultures - that the significant increase in genomic "disorder" that is associated with breast cancer occurs in the transition between the typical hyperplasia and the in situ carcinoma, coinciding with a reduction to a... view more... (2004-09-07)
Scientists identify possible cause of endometriosis
Endometriosis is a condition whereby patches of the inner lining of the womb appear in parts of the body other than the womb cavity. It can cause severe pain and affects approximately 15% of women of reproductive age. Endometriosis is also associated with infertility, with 50% of infertile women affected by the condition. view more (2008-08-06)
Researchers attach genes to minichromosomes in maize
A team of scientists at the University of Missouri-Columbia has discovered a way to create engineered minichromosomes in maize and attach genes to those minichromosomes. view more (2007-05-15)
UT Southwestern researchers identify gene linked to inherited form of fatal lung disease
Researchers at UT Southwestern Medical Center have determined that a mutation in a gene known for its role in defending the lungs against invading pathogens is responsible for some inherited cases of a lethal lung disease affecting older adults. The same mutation may also be associated with lung cancer, the researchers said. view more (2008-12-22)
National Science Foundation congratulates Nobel Laureates in medicine/physiology, chemistry and economics
The National Science Foundation (NSF) congratulates the 2009 Nobel laureates, particularly those who have received NSF funding over the years: Jack W. Szostak, who shared the prize in physiology or medicine; Thomas A. Steitz, who shared the prize in chemistry; and Elinor Ostrom and Oliver E. Williamson who earned the Sveriges Riksbank Prize in... view more... (2009-10-15)
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