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U of Minnesota study finds thalidomide shows promise for treatment of recurrent ovarian cancer
Thalidomide, a drug blamed in the 1950s for causing birth defects, is now showing promise as a safe and effective treatment for women with recurrent ovarian cancer, according to a study led by a University of Minnesota Cancer Center researcher.   view more (2008-02-28)

New study reports increased response to therapy with no added toxicity in treatment of recurrent ovarian cancer
In a study released today at the Society of Gynecologic Oncologists 37th Annual Meeting on Women's Cancer, researchers found the addition of thalidomide to topotecan for the treatment of recurrent ovarian cancer significantly increases the response to therapy and the duration of progression free... view more (2006-03-27)

Keeping cancer at bay: Long-term therapy in the fight against multiple myeloma
There is no known cure for multiple myeloma, so its diagnosis means high-dose chemotherapy followed by repeated treatments with each relapse of the cancer - a watch and wait approach.   view more (2006-11-06)

Thalidomide treatment proves better than conventional chemotherapy for multiple myeloma
When people hear "thalidomide," many think "birth defects," however, evidence has come to light that this once-banned drug can be used as a potent anti-cancer treatment. In a new study, researchers from the University of Bologna, Italy, demonstrate that Thal-Dex (thalidomide... view more (2005-06-21)

Mayo Clinic research shows promise for myeloma patients
Mayo Clinic Cancer Center investigators report that combination therapy with lenalidomide (RevlimidTM) and dexamethasone (combination is called Rev/Dex) looks like a breakthrough treatment for multiple myeloma.   view more (2005-09-02)

New hope for patients with chronic lymphocytic leukemia
Patients treated with lenalidomide for relapsed chronic lymphocytic leukemia (CLL) or disease that no longer responds to chemotherapy have experienced a major response to therapy, according to a phase II study conducted by Asher Chanan-Khan, MD, Department of Medicine, Roswell Park Cancer Institute... view more (2006-12-05)

Results promising for computational quantum chemical methods for drug development
New research, led by a Virginia Tech chemist, may someday help natural-products chemists decrease by years the amount of time it takes for the development of certain types of medicinal drugs.   view more (2007-12-21)

The Biochemist February 2002 issue; THEME: Pretty poisonous
Introduction - The darker end of the spectrum The 'pretty poisonous' entities that are the subject of this issue of The Biochemist have a much darker side - they might be subject to misuse by those with malevolent intent. Toxins and bioregulators have certainly been considered and developed as... view more (2002-02-11)

Chemical coffee maker promises purer medicines
Their method uses pressurised carbon dioxide as a solvent, because it allows chemical reactions which usually create a mixture of products to produce only one. Project leaders Chris Rayner and Tony Clifford believe it could change the way pharmaceuticals are manufactured in the future. "If the... view more (1999-03-15)

Northwestern chemists develop new method for synthesizing anti-cancer flavonoids
Flavonoids. You've heard of them — the good-for-your-health compounds found in plants that we enjoy in red wine, dark chocolate, green tea and citrus fruits. Mother Nature is an ace at making them, producing different ones by the thousands, but no chemist has figured out a good way to... view more (2007-04-05)

Studies attribute recent increase in multiple myeloma survival to novel therapies
Multiple myeloma is one of the most common and devastating bone marrow cancers in the U.S., but survival rates have risen dramatically over the past decade.   view more (2007-11-02)

3-drug combination 'extremely promising' as first-line therapy for multiple myeloma
A new combination of bortezomib (Velcade) and two other drugs is showing a very high response rate in patients newly diagnosed with multiple myeloma, a team headed by Dana-Farber Cancer Institute investigators reported at the annual meeting of the American Society of Hematology.   view more (2007-12-12)

Why were the HIV prevention trials in commercial sex workers abandoned?
One promising approach to help stem the global HIV epidemic is to give commercial sex workers an HIV medication (such as the drug tenofovir) before they have high risk sex in the hope of reducing their chances of becoming infected, an approach called "pre-exposure prophylaxis" (PREP).   view more (2005-07-19)

Scoring system identifies MDS patients who have low-risk disease but a poor prognosis
A new scoring system for a form of leukemia known as myelodysplastic syndrome (MDS) identifies patients who appear to have low-risk disease but actually have poor prospects of survival, researchers at The University of Texas M. D. Anderson Cancer Center report online at the journal Leukemia.   view more (2007-12-27)

Potential diagnostic marker indicates effectiveness of anti-angiogenic drugs
If an anti-angiogenic drug is successfully starving a cancer patient's tumor to death, the number of endothelial cells circulating in the individual's bloodstream will decrease, thus providing a potential biomarker for gauging the medication's effectiveness.   view more (2006-09-18)

Another way to grow blood vessels
Researchers at Dana-Farber Cancer Institute have found a previously unknown molecular pathway in mice that spurs the growth of new blood vessels when body parts are jeopardized by poor circulation.   view more (2008-02-21)

Robot surgery pioneer receives professorship at Imperial College
The world's first Professor of Medical Robotics delivers his Inaugural lecture today at Imperial College, London*1. Pioneer of a host of medical robots including the first clinical use of a robot to actively remove tissue from a patient, Professor Brian Davies will deliver his Inaugural lecture... view more (2002-01-30)

Rare eye-movement disorder may shed light on brain and cardiovascular development
Researchers at Children's Hospital Boston, who specialize in studying the genetics of rare eye-movement disorders, have found a rare genetic syndrome whose implications go far beyond the eye, raising intriguing questions about human cardiovascular and brain development.   view more (2005-09-12)

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