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Brain study may lead to improved epilepsy treatments
Using a rodent model of epilepsy, researchers found one of the body's own neurotransmitters released during seizures, glutamate, turns on a signaling pathway in the brain that increases production of a protein that could reduce medication entry into the brain.   view more (2008-04-15)

Targeting key proteins of carcinogenesis
Misfolded and disused proteins are eliminated by a cellular shredder called the proteasome. The cell labels the proteins it wants to dispose with Ubiquitin (Ub) in order to avoid the unwanted degradation of still needed proteins.   view more (2007-06-25)

Researchers identify mechanism used by gene to promote metastasis in human cancer cells
Virginia Commonwealth University Institute of Molecular Medicine and VCU Massey Cancer Center researchers have discovered how a gene, melanoma differentiation associated gene-9/syntenin (mda-9/syntenin), interacts with an important signaling protein to promote metastasis in human melanoma cells, a... view more (2008-09-30)

Gladstone scientists identify single microRNA that controls blood vessel development
Scientists from the Gladstone Institute of Cardiovascular Disease (GICD) and UCSF have identified a key regulatory factor that controls development of the human vascular system, the extensive network of arteries, veins, and capillaries that allow blood to reach all tissues and organs.   view more (2008-08-12)

What makes a fungus virulent? It's lipase
Infection with the fungus Candida parapsilosis is a major problem for individuals in intensive care units, as well as for premature infants and immunocompromised adults. Despite this, little is known about which of its genes account for its virulence.   view more (2007-09-14)

Deadly gas can protect the heart
Joint release from Northwick Park Institute for Medical Research and the University of Sheffield Scientists have developed a new technology based on carbon monoxide delivery that may protect the heart following a heart attack and prevent rejection of transplanted organs. Researchers from Northwick... view more (2003-08-18)

A protein interaction map for a better insight in cancer development
With the completion of the genome sequence of a number of organisms, analysis of the gene products, the proteins, is the on-going challenge.   view more (2005-02-28)

European Commission proposes strict ethical guidelines on EU funding of human embryonic stem cell research
Today the Commission adopted a proposal for guidelines on EU-funded human embryonic stem cell research. The EU 6th Research Framework Programme (FP6 2003-2006), as adopted by the Council of Ministers and the European Parliament in 2002, allows for the funding of human embryonic stem cell research... view more (2003-07-14)

First steps towards a vaccine for pancreatic cancer
Research carried out in the United States has raised the hope that one day there could be a vaccine against pancreatic cancer - one of the most difficult cancers to treat successfully.   view more (2003-09-20)

Smoked cannabis proven effective in treating neuropathic pain
Smoked cannabis eased pain induced in healthy volunteers, according to a study by researchers at the University of California, San Diego (UCSD) Center for Medical Cannabis Research (CMCR.) However, the researchers found that less may be more.   view more (2007-10-25)

Intensity-modulated radiation therapy reduces side effects for cervical cancer
Preliminary results from a University of Pittsburgh study evaluating extended-field intensity-modulated radiation therapy (IMRT) for cervical cancer found that it resulted in significantly reduced side effects and outcomes comparable to standard radiotherapy.   view more (2006-11-08)

Value of community treatment orders in doubt
Compulsory psychiatric treatment in the community is thought to reduce the use of health services by patients with mental health disorders. However, a study in this week's BMJ raises questions about the effectiveness of such an invasive procedure. Researchers matched 228 psychiatric patients placed... view more (2002-05-22)

Mass. General researchers identify master cardiac stem cell
Researchers from the Massachusetts General Hospital (MGH) Cardiovascular Research Center have discovered what appears to be a master cardiac stem cell, capable of differentiating into the three major types of cells that make up the mammalian heart.   view more (2006-11-27)

Report suggests allopurinol may lower blood pressure in teens with hypertension
The drug allopurinol, which lowers uric acid levels, appears to reduce blood pressure in adolescents with newly diagnosed hypertension, according to a preliminary report in the August 27 issue of JAMA.   view more (2008-08-27)

A new pathway for halting neuronal death in Huntington's disease
The body is an extremely complex puzzle in which every piece plays a critical role. Should pieces disappear harmony is compromised. Such is the case with certain neurodegenerative diseases; when neurons suddenly die, the body's ability to function properly is jeopardized. CNRS (1) and INSERM... view more (2002-06-12)

Part of drug trial for patients with atrial fibrillation discontinued
Study treatments for the ACTIVE W trial of the ACTIVE (Atrial Fibrillation Clopidogrel Trial with Irbesartan for Prevention of Vascular Events) program have been discontinued due to a significant difference in efficacy, in favour of the standard oral anticoagulation (OAC) over antiplatelet therapy... view more (2005-09-07)

Stem Cells from Monkey Teeth Can Stimulate Growth and Generation of Brain Cells
Researchers at the Yerkes National Primate Research Center, Emory University, have discovered dental pulp stem cells can stimulate growth and generation of several types of neural cells. Findings from this study, available in the October issue of the journal Stem Cells, suggest dental pulp stem... view more (2008-11-12)

A pathway towards cures for Parkinson`s and cancer
Researchers studying the Hedgehog signaling pathway have identified small molecules that could form the foundations of exciting new treatments for Parkinson's disease and certain cancers. New research published in Journal of Biology - the open access journal for exceptional research - has... view more (2002-11-01)

Eisai announces Phase II data on E7389, a potential new therapy for the treatment of breast cancer
Researchers today presented preliminary safety and efficacy data for E7389 in the treatment of advanced, refractory breast cancer during the San Antonio Breast Cancer Symposium.   view more (2005-12-12)

Media Invitation to Human Genome Meeting
As we enter what has been dubbed the "post-genomic" era, HGM2004, the annual meeting of the Human Genome Organisation (HUGO), will focus on the future of genome research. The 2004 meeting will look at what will come next in our understanding of human genetics, considering the hopes for... view more (2004-02-06)

Heart attacks are not all bad
New research shows that heart attack survivors and their partners actually feel they benefited from the attack.   view more (2004-08-23)

Nanoparticles carry cancer-killing drugs into tumor cells
University of Michigan scientists have created the nanotechnology equivalent of a Trojan horse to smuggle a powerful chemotherapeutic drug inside tumor cells - increasing the drug's cancer-killing activity and reducing its toxic side effects.   view more (2005-06-15)

Potential new approach to treat cognitive impairments in schizophrenia
A new study reports important evidence for a potential new treatment approach for those diagnosed with schizophrenia. Schizophrenia is considered one of the most devastating of the major psychiatric disorders, which has three distinct facets, often referred to as "positive"... view more (2007-09-25)

Lowering Body Temperature Could Aid Standard Stroke Treatment
University of Cincinnati (UC) scientists have developed a model that could help physicians combine current clot-busting medication with below-normal body temperatures (hypothermia) to improve the treatment of ischemic stroke patients.   view more (2007-05-18)

Press Invitation: The science of stem cells - December Symposium at Imperial College
PRESS INVITATION 28 November 2000 As the British parliament prepares to debate a change in the law to allow stem cells from human embryos to be used in research, Imperial College researchers will gather at a Symposium in December to discuss the science behind stem cells, and examine their... view more (2000-11-29)
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