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Scientific advance establishes ‘proof of principle’ that prion diseases might be prevented using monoclonal antibody technology
UK scientists have made a major scientific advance by establishing proof of principle that the development of prion disease can be prevented in mice using monoclonal antibodies (mAbs). The work lays the foundation for further research to explore the potential of mAbs to treat specific prion... view more (2003-03-03)

New standards could cut number of malnourished children on feeding programs
The introduction of new standards to assess nutrition in children could lead to confusion and a cut in the numbers of malnourished children eligible for emergency feeding programmes, warn researchers in this week's BMJ.   view more (2007-04-06)

NYU researchers developing molecular delivery vehicles for genetic therapies
Researchers at New York University are working to develop molecular delivery vehicles that can be used to transport nucleic acids into diverse cell types, which may lead to eventual applications in genetic therapies.   view more (2006-11-14)

Scientists a step closer to understanding how anaesthetics work in the brain
An important clue to how anaesthetics work on the human body has been provided by the discovery of a molecular feature common to both the human brain and the great pond snail nervous system, scientists say today.   view more (2007-07-20)

Leukemia drug could save lives of stroke patients
The drug tPA is the most effective treatment currently available for stroke patients, but its safety is limited to use within the first three hours following the onset of symptoms.   view more (2008-06-23)

MIT develops 'Anklebot' for stroke patients
Clinical trials have already shown that an MIT robotic arm can help stroke patients regain movement faster. Now MIT pioneers in the field of robotic therapy are hoping a robotic gym full of machines targeted at different parts of the body will significantly improve stroke patients' movement in... view more (2005-07-06)

Swedes in favor of genetic engineering but against spread of genetic information
Swedes are becoming more and more favorably inclined toward genetic engineering. Two out of three Swedes now accept genetic engineering. This makes Swedes the people with the most favorable views in the EU. This has been demonstrated in a European research project in which three researchers from... view more (2003-08-26)

Scientists take a step nearer to creating an artificial egg using a somatic cell
Scientists believe that they are an important step nearer to success in creating an artificial egg from the combination of the nucleus of a somatic cell and an oocyte which has had its DNA-carrying nucleus removed, a conference of international fertility experts heard today (Tuesday 1 July). Dr... view more (2003-06-28)

Simple chemical procedure augments therapeutic potential of stem cells
Adult stem cells resemble couch potatoes if they hang out and divide in a dish for too long. They get fat and lose key surface proteins, which interferes with their movement and reduces their therapeutic potential. Now, via a simple chemical procedure, researchers have found a way to get these... view more (2008-10-31)

Twice daily imatinib could improve outcome for people with specific form of gastro-intestinal cancer (pp 1101, 1127)
Results of a randomised trial in this week's issue of THE LANCET suggest that a single daily 400 mg dose of imatinib-known to be a first-choice treatment for gastro-intestinal stromal tumours (GIST)-is sufficient to induce a therapeutic response; a doubling of a daily dose can slightly improve... view more (2004-09-22)

Candy-coating keeps proteins sweet
Sugar-frosting isn't just for livening up boring bran flakes; it can also preserve important therapeutic proteins. Researchers at the National Institute of Standards and Technology (NIST) have developed a fast, inexpensive and effective method for evaluating the sugars pharmaceutical companies use... view more (2008-08-20)

Novel and Effective Treatment for Soft Tissue Sarcoma in Children
Rhabdomyosarcoma is a highly malignant aggressive form of soft tissue cancer in children, the causes of which are currently unknown. Although the fibrous growths can be found all over the body they commonly develop around the head, neck, bladder and testes in young boys. The most common age for... view more (2004-07-15)

Carnegie Mellon researchers to develop new drug delivery system
Carnegie Mellon University's Stefan F. Zappe is using adult neural stem cells to develop a new stem cell-based drug delivery therapy that may ultimately help treat a variety of inherited genetic disorders like Hunter syndrome.   view more (2007-11-05)

Drug commonly used to treat bipolar disorder dramatically increases lifespan in worms
Nematode worms treated with lithium show a 46 percent increase in lifespan, raising the tantalizing question of whether humans taking the mood affecting drug are also taking an anti-aging medication.   view more (2007-10-31)

Removal of superficial tumours in oesophagus by endoscopy can avoid complete extirpation of this part of the digestive tract
The removal through endoscopy of tumours that affect only the superficial layers of the oesophagus can avoid complete extirpation of this part of the digestive tract.   view more (2008-04-11)

Scientists solve mystery of polyketide drug formation
Many top-selling drugs used to treat cancer and lower cholesterol are made from organic compounds called polyketides, which are found in nature but historically difficult for chemists to alter and reproduce in large quantities.   view more (2008-04-02)

More than 80% of patients manage to stop discomfort from tinnitus and can lead a normal life again
It is estimated that between 10 and 17% of the population has suffered tinnitus at some time in their lives, according to a number of international studies.   view more (2007-06-26)

Purdue scientists treat cancer with RNA nanotechnology
Using strands of genetic material, Purdue University scientists have constructed tiny delivery vehicles that can carry anticancer therapeutic agents directly to infected cells, offering a potential wealth of new treatments for chronic diseases.   view more (2005-09-14)

Egg donation for stem cell research — balancing the risks and benefits
In the wake of the scandal involving fraudulent cloning research, concerns about the welfare of women donating eggs for research purposes have arisen.   view more (2006-06-20)

Large dose dexamethasone plays important roles in severe acute pancreatitis
Severe acute pancreatitis (SAP) is a fatal systemic disease featuring acute onset, serious conditions, high incidence of complications and 20 - 30% mortality, mainly due to multiple organ failure at its early stage.   view more (2007-11-05)

Sickle cell disease corrected in human models using stem cell-based gene therapy
In a study to be published in the January 2006 issue of Nature Biotechnology, researchers led by a team of scientists at Memorial Sloan-Kettering Cancer Center have devised a novel strategy that uses stem cell-based gene therapy and RNA interference to genetically reverse sickle cell disease (SCD)... view more (2005-12-29)

Researchers discover mechanism that may enable stem cell-based treatment for eye disorders
In discovering a protein that helps organize the development of the retina, UC Irvine researchers have found a new molecular mechanism that may allow for stem cell-based therapies to treat eye disorders such as retinal degeneration.   view more (2005-06-24)

Biacore launches new generation system for protein interaction analysis
Unmatched performance of Biacore T100 supports critical decision-making from research through to manufacturing and QC   view more (2005-02-16)

Extra-aggressive form of idiopathic pulmonary fibrosis identified
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disorder from which most patients die within 5 years after diagnosis. The disease is characterized by the insidious onset of dyspnea or cough and usually evolves slowly.   view more (2007-05-30)

SPECIFIC GENE MUTATION LINKED TO CROHN'S DISEASE (pp 1902, 1925)
Genetic susceptibility to Crohn's disease is likely to be the result of an insertion mutation into a specific gene on chromosome 16, conclude authors of a fast-track study published in this week's issue of THE LANCET. In 1996, genetic linkage of inflammatory bowel disease (IBD) to chromosome 16... view more (2001-06-13)
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