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Properties of Unusual Virus Revealed in Researchers
A team of researchers from Penn State University and the University of Chicago has uncovered clues that may explain how and why a particular virus, called N4, injects an unusual substance -- an RNA polymerase protein -- into an E. coli bacterial cell. The results, which are published in the current issue of the journal Molecular Cell, contribute... view more... (2008-12-09)
Evolution is driven by gene regulation
It is not just what's in your genes, it's how you turn them on that accounts for the difference between species - at least in yeast - according to a report by Yale researchers in this week's issue of Science. view more (2007-08-10)
Research elucidates mechanism by which gene expression may be altered in drug addiction
Dr. Judith A. Potashkin, Ph.D. and her colleagues at Rosalind Franklin University of Medicine and Science recently completed a study investigating one of the changes in gene expression that occurs when individuals take addictive drugs. view more (2007-09-05)
Drug not effective in preventing bypass vein clogging
A new drug, edifoligide, designed to prevent the clogging of veins used in coronary bypass surgery was no more effective than a placebo, according to the results of a Phase III clinical trial led by researchers at Duke Clinical Research Institute (DCRI). view more (2005-11-14)
Mayo Clinic Researchers Find That Protein Believed to Protect Against Cancer Has a Mr. Hyde Side
In a biological rendition of fiction's Strange Case of Dr. Jekyll and Mr. Hyde, researchers from the Mayo Clinic campus in Florida and Harvard Medical School have found that a protein thought to protect against cancer development can actually spur the spread of tumors. view more (2009-09-04)
Teamwork between 2 key proteins necessary for normal development and regulation of red blood cells
Virginia Commonwealth University researchers studying hemoglobin genes, mutations of which play a role in genetic blood disorders like sickle cell anemia and beta-thalassemia, have identified two proteins that are responsible for regulating overlapping groups of genes during the development of red blood cells. view more (2007-08-07)
UCSF team closer to creating safe embryonic-like stem cells
A team of UCSF researchers has for the first time used tiny molecules called microRNAs to help turn adult mouse cells back to their embryonic state. view more (2009-04-13)
Genetic interactions are the key to understanding complex traits
In recent years, genetic studies have uncovered hundreds of DNA variations linked to common diseases, such as cancer or diabetes, raising the prospect that scientists can gauge disease risk based on information in an individual's genome. view more (2009-01-23)
Opening and closing the genome
At any given time, most of the roughly 30,000 genes that constitute the human genome are inactive, or repressed, closed to the cellular machinery that transcribes genes into the proteins of the body. view more (2007-02-26)
'Junk' DNA proves functional
In a paper published in Genome Research on Nov. 4, scientists at the Genome Institute of Singapore (GIS) report that what was previously believed to be "junk" DNA is one of the important ingredients distinguishing humans from other species. view more (2008-11-05)
Internal Clock, External Light Regulate Plant Growth
Most plants and animals show changes in activity over a 24-hour cycle. Now, for the first time, researchers have shown how a plant combines signals from its internal clock with those from the environment to show a daily rhythm of growth. view more (2007-07-10)
A potential therapeutic agent for hepatic fibrosis
Accumulating evidence suggests that connective tissue growth factor (CCN2) plays a central role in fibrotic conditions in many organ systems. view more (2009-08-26)
The evolution of food plants: Genetic control of grass flower architecture
Scientists are interested in understanding genetic control of grass inflorescence architecture because seeds of cereal grasses (e.g. rice, wheat, maize) provide most of the world's food. view more (2006-01-23)
HIV inserts into human genome using a DNA-associated protein
A human DNA-associated protein called LEDGF is the first such molecule found to control the location of HIV integration in human cells. view more (2005-11-28)
New gene silencing pathway found in plants
Biologists at Washington University in St. Louis have made major headway in explaining a mechanism by which plant cells silence potentially harmful genes. view more (2008-11-18)
Scientists map key landmarks in human genome
Dana-Farber Cancer Institute researchers have developed a powerful method for charting the positions of key gene-regulating molecules called nucleosomes throughout the human genome. view more (2007-01-17)
UT Southwestern researchers find alterations in brain's circuitry caused by cocaine
Cocaine causes specific alterations in the brain's circuitry at a genetic level, including short-term changes that result in a high from the cocaine, as well as long-term changes seen in addiction. view more (2005-10-24)
Soy protein reduces effects of diabetes on liver
A group of researchers from Mexico has discovered that a diet rich in soy protein may alleviate fatty liver, a disease which often accompanies diabetes. view more (2005-09-07)
Gene that makes people 'early to bed and early to rise' demystified
The recent discovery that a mutant "clock" gene made some people "early to bed and early to rise," a condition known as familial advanced sleep phase syndrome (FASPS), offered one of the first glimpses into the genetic basis of sleep in humans. view more (2007-01-12)
Oocyte-specific gene mutations cause premature ovarian failure
Mutations in a gene called FIGLA cause premature ovarian failure in at least a percentage of women who suffer from the disorder, said researchers from Baylor College of Medicine in Houston and Shandong University in China in a report that appears online today in the American Journal of Human Genetics. view more (2008-05-23)
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