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New pathway provides more clues about BRCA1 role in breast cancer
A breast cancer gene's newly discovered role in repairing damaged DNA may help explain why women who inherit a mutated copy of the gene are at increased risk for developing both breast and ovarian cancer. view more (2008-01-16)
Computation to unravel how genes are regulated and shed light on how cells become different
A closer alliance between computational and experimental researchers is needed to make progress towards one of biology's most challenging goals, understanding how epigenetic marks contribute to regulation of gene expression. view more (2008-04-11)
Small molecules mimic natural gene regulators
In the quest for new approaches to treating and preventing disease, one appealing route involves turning genes on or off at will, directly intervening in ailments such as cancer and diabetes, which result when genes fail to turn on and off as they should. view more (2009-06-04)
When it comes to gene transcription, random pauses aren't quite so random, study finds
Of the thousands of proteins produced in our cells, few are as important as the enzyme RNA polymerase (RNAP), which has the unique ability to faithfully copy genetic information from DNA. view more (2006-06-16)
Turmeric prevents experimental rheumatoid arthritis, bone loss, University of Arizona study shows
An ancient spice, long used in traditional Asian medicine, may hold promise for the prevention of both rheumatoid arthritis and osteoporosis, according to a recently completed study at The University of Arizona College of Medicine. view more (2006-10-30)
New study expands understanding of the role of RNA editing in gene control
For many years, scientists thought gene activity was relatively straightforward: Genes were transcribed into messenger RNA, which was processed and translated into the proteins of the body. view more (2005-12-27)
LSUHSC research may benefit diabetes by increasing understanding of how to control islet cell growth
Michael Lan, PhD, Professor of Pediatrics and Genetics at LSU Health Sciences Center New Orleans, is the senior author of a paper revealing the molecular mechanism of how a protein determines the fate of the cells that make and release insulin. view more (2009-02-18)
Tool developed to silence genes in specific tissues using RNAi
Researchers at The University of Texas M. D. Anderson Cancer Center say they have jumped a significant hurdle in the use of RNA interference (RNAi), believed by many to be the ultimate tool to both decode the function of individual genes in the human genome and to treat disease. view more (2006-01-17)
Scientists shed light on inner workings of human embryonic stem cells
Scientists at UC Santa Barbara have made a significant discovery in understanding the way human embryonic stem cells function. view more (2009-05-01)
Early-stage gene transcription creates access to DNA
A gene contained in laboratory yeast has helped an international team of researchers uncover new findings about the process by which protein molecules bind to control sequences in genes in order to initiate gene expression, according to findings reported in the journal Nature. view more (2008-10-07)
Researchers discover a new pathway that regulates inflammation
Inflammation, the body's earliest response to damage or infection, can aid the healing process and trigger an immune response against invading pathogens. But inflammation gone awry can also undermine health, as in diseases such as rheumatoid arthritis or asthma. view more (2009-03-12)
Mean new microRNA data analysis method gives sharper results
Our understanding of the importance of microRNAs in regulating gene expression is expanding, and with it our requirement for robust methods to measure their expression levels. view more (2009-06-16)
Scientists Shed Light on Long-Distance Signaling in Developing Neurons
A longstanding puzzle in neurodevelopment may have yielded up a key secret. A team led by scientists at Weill Cornell Medical College says they have determined how events at the very tips of the developing neuron's long, skinny axon affect gene transcription back in the cell's distant nucleus. view more (2008-02-20)
Protein key to neuro-regeneration
Researchers at the Peninsula Medical School in the South West of England, University College London, the San Raffaele Scientific Institute in Milan and Cancer Research UK, have for the first time identified a protein that is key to the regeneration of damage in the peripheral nervous system and which could with further research lead to... view more... (2008-05-21)
Cancer drug may improve memory in Alzheimer's patients
A drug now used to treat cancer may also be able to restore memory deficits in patients with Alzheimer's disease. view more (2009-09-08)
Controlling embryonic fate by association
Association determines fate in embryonic stem cells, said Baylor College of Medicine researchers in a report that appears in the current issue of the journal Nature Cell Biology. view more (2008-05-05)
MicroRNA may have fail-safe role in limb development
A tiny strand of molecules plays a role in how our arms and legs develop and grow-a finding that sheds light on perplexing bits of material once dismissed as genetic "junk," say scientists at the University of Florida and Harvard University. view more (2005-12-02)
Two Genes Are Important Key to Regulating Immune Response
A research team at Weill Cornell Medical College in New York City has identified two genes that may be crucial to the production of an immune system cytokine called interleukin-10 (IL-10). view more (2008-01-02)
How embryonic stem cells maintain their identity
Two studies in the April 21, 2006 Cell report new details of the "genetic program" that affords embryonic stem cells the flexibility to give rise to any cell type in the body. view more (2006-04-21)
HATS off to combat asthma
Two University of Nottingham studies exploring the causes and treatment of asthma and Chronic Obstructive Pulmonary Disease (COPD) could lead to the development of drugs to battle these debilitating conditions. view more (2007-12-05)
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