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Study shows common vitamin and other micronutrient supplements reduce risks of TB recurrence
New findings show a link between micronutrient supplementation and reduced risk of recurrence during tuberculosis chemotherapy, according to a study published in the June 1 issue of The Journal of Infectious Diseases, now available online.   view more (2008-04-28)

Tuberculosis risks for health workers in developing countries
Latent infection with tuberculosis is common and some infected people develop the active form of the disease. Health-care workers (HCWs) can become infected, develop active disease, and c an pass their infection on to patients and others.   view more (2006-12-26)

Pitt-led Researchers Find Source of Drug-Tolerant Tuberculosis Possibly Behind TB Relapses, Intensity of Treatment
University of Pittsburgh-led researchers discovered that the primary bacteria behind tuberculosis can grow on surfaces and that drug-tolerant strains flourish in these bacterial communities, the research team recently reported in "Molecular Microbiology."   view more (2008-06-12)

Pilot study reinforces use of portable anteroom HEPA filtration
Amidst an increase in new tuberculosis cases, researchers have begun investigating the effectiveness of new operating room filtration systems designed to protect staff and patients.   view more (2008-05-07)

US investment in tuberculosis control abroad pays off at home
A new study to be published in tomorrow's New England Journal of Medicine shows that United States investment in tuberculosis (TB) treatment abroad saves lives and money at home.   view more (2005-09-08)

Abandoned bones suggest TB wiped out leprosy in battle of killer diseases
The spread of tuberculosis may have killed off leprosy in Europe in the Middle Ages, according to research published in the latest issue of the Royal Society Proceedings B.   view more (2005-02-07)

Patient adherence for successful tuberculosis treatment
Nearly 2 million people die from tuberculosis each year, mainly in the poorest countries. The pathogen, Koch's bacillus, can pass easily by aerial infection from one individual to another.   view more (2007-03-28)

In early childhood, continuous care by 1 doctor improves delivery of health screenings
Children examined by the same doctor during their first six months of life are more likely to receive appropriate preventive health screenings -- for lead poisoning, anemia and tuberculosis -- by age two.   view more (2008-03-03)

Shining sweetness â€" fluorescent sugars shed new light on future TB therapies
The discovery that fluorescent sugar molecules mark important enzymes of the tuberculosis bacillus will facilitate investigation of the potential importance of the enzymes for future tuberculosis (TB) therapies. This insight is a gratifying "by-product" of research at the Institute of... view more (2003-05-19)

Studies Suggest New Targets for Tuberculosis Treatments
With the hope of designing more effective treatments for tuberculosis (TB), scientists from the U.S. Department of Energy's Brookhaven National Laboratory and collaborating institutions have published the first detailed reports on the biochemistry and structure of a protein-cleaving complex that is... view more (2006-03-07)

ID, HIV experts urge more resources for TB
In honor of World TB Day 2008 (March 24), the Infectious Diseases Society of America (IDSA) and the HIVMA Medicine Association (HIVMA) are urging U.S. policymakers to step up the fight against tuberculosis by committing substantial resources against the disease both at home and abroad.   view more (2008-03-24)

TB relapse due to low weight gain after initial treatment
Among tuberculosis (TB) patients who were underweight when diagnosed, those who subsequently regained less than five percent of their weight during the first two months of treatment had a significantly increased risk of disease relapse, according to results from a large study.   view more (2006-08-01)

New chemical can kill latent tuberculosis bacteria
Success in the laboratory suggests that a new compound can point the way to preventing active tuberculosis in people infected with the latent form of the bacterium, says a team led by researchers at Weill Cornell Medical College in New York City.   view more (2008-03-17)

Predicting TB outbreaks based on the first 2 cases
Outbreaks of tuberculosis (TB) may be able to be identified by looking at certain characteristics of the first two patients, according to new research.   view more (2008-07-01)

Hopkins scientist to direct international studies of antibiotic as new treatment for tuberculosis
A Johns Hopkins infectious disease expert will lead two international studies of the effectiveness of the antibiotic moxifloxacin as a new treatment for tuberculosis, the highly contagious bacterial disease that kills more than 2 million people worldwide each year and is the leading cause of death... view more (2005-10-18)

Medical residents unclear about TB guidelines
US medical residents are not proficient at diagnosing and managing tuberculosis (TB), according to a report published in the online open access journal, BMC Infectious Diseases.   view more (2007-08-02)

New Approaches To HIV Treatment In Less-developed Countries (pp 404, 410)
Two Viewpoint articles in this week's issue of THE LANCET highlight how the use of highly-active antiretroviral therapy (HAART) for HIV-1 treatment - currently only widely available in industrialised countries - could become accessible in less-developed settings. Both articles suggest new... view more (2001-08-01)

UNC, Harvard develop inhaled TB vaccine
A new tuberculosis vaccine successfully tested at the University of North Carolina at Chapel Hill is easier to administer and store and just as effective as one commonly used worldwide.   view more (2008-03-17)

Soaring rates of tuberculosis in children living in London
Rates of tuberculosis (TB) have risen 130 per cent in children living in London over the past decade, reports a study in Archives of Disease in Childhood.   view more (2002-03-21)

Medical residents score poorly in diagnosing and managing tuberculosis
When quizzed about their knowledge in diagnosing tuberculosis and deciding on the best treatment, medical residents in Baltimore and Philadelphia get almost half the answers wrong, according to a survey by TB disease experts at Johns Hopkins and elsewhere.   view more (2007-08-02)

K-State professor developing new strategies for delivery of drugs to fight, treat tuberculosis
It has been identified by the World Health Organization as the most dangerous infectious disease, causing more deaths - more than 2 million a year - than any other single infection. "It" is Mycobacterium tuberculosis.   view more (2005-08-31)

WHO 2003-2008: A Programme Of Quiet Thunder Takes Shape (p 179)
This week's editorial looks ahead to the future of WHO as Dr J W Lee is poised to take over as leader of the only global health agency from Gro Harlem Brundtland on July 21. Lee's priorities are discussed: 'The priority among priorities is HIV/AIDS. The phrase "3-by-5" peppers the... view more (2003-07-16)

Preventing tuberculosis reactivation
Tuberculosis (TB) is the leading cause of death due to infectious disease in the world today. It is estimated that 2 billion people are currently infected, and although most people have latent infection, reactivation can occur.   view more (2007-10-18)

Association of tuberculosis with smoking and indoor air pollution
Smokers have an increased risk of tuberculosis (TB) infection, TB disease, and of dying from TB compared to people who do not smoke.   view more (2007-01-16)

International Excellence Team To Work On Infectious Disease At The Gulbenkian Science Institute, In Portugal
The Gulbenkian Science Institute (IGC), in Portugal, is to host one of the 20 excellence teams approved by the European Commission in the 2004 call. The team, led by IGC researcher Gabriela Gomes, has been awarded a grant of approximately one million and nine hundred thousand euro, to be used over... view more (2005-01-31)

The structure of a key enzyme for infectious diseases solved at ESRF
A European team of scientists from the University of Dundee (UK), the Technical University of Munich (Germany) and the European Synchrotron Radiation Facility, ESRF, (France) have determined the structure of a key target enzyme for novel drug development to treat infectious diseases including... view more (2003-08-12)

Review study finds association between tobacco smoking and increased risk of tuberculosis
Tuberculosis (TB) is an infectious disease that causes an estimated 2 million deaths each year. The majority of those deaths occur in developing countries, home to more than 900 million of the world's 1.1 billion smokers.   view more (2007-01-16)

Portuguese and British scientists develop mathematical model that explains variability in tuberculosis vaccine efficacy
Scientists at the Instituto Gulbenkian de Ciencia (IGC), in Portugal, together with colleagues at the Universities of Lisbon and Warwick, in the United Kingdom, have developed a mathematical model that explains why the tuberculosis (TB) vaccine is ineffective in many of the developing countries.... view more (2004-03-03)

Einstein researchers find potential new drugs for tuberculosis
Researchers at the Albert Einstein College of Medicine of Yeshiva University have synthesized chemicals that are up to 10 times more effective than isoniazid, the leading anti-tuberculosis drug.   view more (2006-03-27)

Most ancient case of tuberculosis found in 500,000-year-old human; points to modern health issues
Although most scientists believe tuberculosis emerged only several thousand years ago, new research from The University of Texas at Austin reveals the most ancient evidence of the disease has been found in a 500,000-year-old human fossil from Turkey.   view more (2007-12-07)

The complexities of genetic susceptibility to tuberculosis revealed
Researchers working in Vietnam have identified a genetic variant that predisposes people to developing a lethal form of tuberculosis (TB), tuberculous meningitis, if they are infected with a strain of TB known as the Beijing strain.   view more (2008-03-28)

Government is treating the symptoms and not fighting the causes of infectious diseases, say scientists
The Microbiology Awareness Campaign gathered momentum yesterday at the House of Lords when scientists informed Peers and MPs that new and re-emerging infectious diseases could spell trouble if not tackled soon. The experts said that without targeted government funding for microbiological research,... view more (2005-03-02)

Better and faster: Distinguishing non-TB pulmonary disease from TB
A diagnostic kit shows new promise for distinguishing between tuberculosis (TB) and its infections from disease caused by related mycobacteria family, which mimic TB and other lung disease in symptoms but require distinctly different clinical treatments.   view more (2008-04-01)

A new more effective tuberculosis screening test for HIV victims
World Health Organization (WHO) figures show that each year an estimated 9 million new cases of tuberculosis (TB) arise in the world.   view more (2008-03-06)

Two centres for infectious diseases established
The Netherlands Organisation for Scientific Research (NWO) has awarded a so-called centre subsidy to two research centres which are currently being established. Each centre will receive a total of 1.35 million euros. These funds must be used by the centres over the next five years to carry out... view more (2004-02-05)

DOTS Show the Way to Tackle the Toughest TB.
New research has shown for the first time that the spread of multi drug-resistant TB can be halted through a well executed standard treatment programme. Bacterial fingerprinting techniques used to track disease transmission in a southern Mexico community revealed that all categories of tuberculosis... view more (2005-04-01)

Inhaled tuberculosis vaccine more effective than traditional shot
A novel aerosol version of the most common tuberculosis (TB) vaccine, administered directly to the lungs as an oral mist, offers significantly better protection against the disease in experimental animals than a comparable dose of the traditional injected vaccine, researchers report this week in... view more (2008-03-13)

Circulation of 'disaster myths' in Haiti could hinder appropriate disposal of bodies
Myths about the infectious disease threat posed by dead bodies could lead to insensitive and inappropriate treatment of victims' bodies following the floods in Haiti, and need to be checked, according to a public health researcher who has studied the potential risks at length.   view more (2004-09-30)

Treatment outcomes of patients with HIV and tuberculosis
In a retrospective study of 700 patients with culture-positive tuberculosis (TB), relapse rates were found to be significantly higher in HIV-infected patients compared to HIV-uninfected patients following a rifamycin-based regimen.   view more (2007-06-01)

NIAID describes research priorities to fight drug-resistant tuberculosis
Tuberculosis (TB) has long been one of the world's great killers. Now, forms of drug-resistant TB--multidrug (MDR) and extensively drug-resistant (XDR)--are occurring at an ominous and accelerating rate.   view more (2008-04-23)

Simple strategy could prevent half of deadly tuberculosis infections
By using a combination of inexpensive infection control measures, hospitals around the world could prevent half the new cases of extensively drug resistant tuberculosis (XDR TB), according to a new study in The Lancet by researchers at Yale School of Medicine.   view more (2007-12-19)

AIDS, TB, malaria and bird flu spread unchecked in Burma
Government policies in Burma that restrict public health and humanitarian aid have created an environment where AIDS, drug-resistant tuberculosis, malaria and bird flu (H5N1) are spreading unchecked.   view more (2006-03-28)

New blood tests for TB show exposure to disease while tuberculin skin tests do not
Two new interferon-gamma blood test assays to detect latent tuberculosis infection (LTBI) showed customers were exposed to a supermarket employee in Holland who had smear-positive tuberculosis, while traditional tuberculin skin tests (TST) did not, according to a large contact study.   view more (2007-03-15)

Vaccine hope for malaria
One person dies of it every 30 seconds, it rivals HIV and tuberculosis as the world's most deadly infection and the vast majority of its victims are under five years old.   view more (2007-05-24)

US soldiers in high-tuberculosis areas face new epidemic: false positives
U.S. Army service members are increasingly deployed in regions of the world where tuberculosis (TB) is rampant, such as Iraq and Afghanistan, and the military now faces a growing medical problem.   view more (2008-05-30)

Tuberculosis breaches borders, but not public health
Immigrants from countries with high rates of tuberculosis who move to countries of low TB incidence do not pose a public health threat to native citizens, according to researchers in Norway, who analyzed the incidence and genetic origins of all known cases of TB in the country between 1993 and 2005.   view more (2007-11-01)

Uprooting and replanting the tree of life
A new theory on the evolution of ancient microbes is set to challenge widespread scientific views of early life on earth and could overturn previous interpretations of the huge bank of molecular taxonomic data that has been built up in recent years, according to research published today in the... view more (2002-01-08)

Newly Identified Mechanism Helps Explain Why People of African Descent Are More Vulnerable to Tuberculosis
A team of scientists has identified a cellular mechanism that may help explain the puzzle of why people of African descent are more susceptible to tuberculosis infection and why, once infected, they develop more severe states of the disease than whites.   view more (2006-02-27)

Faster, more accurate tuberculosis test developed
Researchers from the Johns Hopkins Bloomberg School of Public Health, the Imperial College London, Universidad Peruana Cayetano Heredia, in Lima, Peru, and other institutions have developed a simple and rapid new tuberculosis (TB) test.   view more (2006-10-12)

Global Fund must fund salaries of health workers to deliver HIV, TB and malaria treatments
In this week's PLoS Medicine, a team of international health experts issue a bold call to the Global Fund to Fight AIDS, TB, and Malaria: fund the salaries of health workers or else risk a situation in which medicines for these three diseases are made available in poor countries but there are no... view more (2007-04-17)
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