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Therapeutic peptide frees the protein p73 to kill tumor cells The protein p53 suppresses tumor development by potently inducing tumor cell death, making it an obvious target for anticancer therapeutics. view more (2007-03-09)
Standard treatment for prostate cancer may encourage spread of disease A popular prostate cancer treatment called androgen deprivation therapy may encourage prostate cancer cells to produce a protein that makes them more likely to spread throughout the body, a new study by Johns Hopkins researchers suggests. view more (2007-10-01)
Study shows big power of small RNAs, not just proteins, in halting cancer Cold Spring Harbor Laboratory (CSHL) researchers led by Lin He, Xingyue He, and Professor and Howard Hughes Medical Investigator (HHMI) Greg Hannon have identified a family of micro RNAs (miRNAs) that enable a critical tumor suppressor network, called the p53 pathway, to fight cancer growth. view more (2007-06-07)
Cancer researchers link DICER1 gene mutation to rare childhood cancer Research published today in Science Express from the journal Science demonstrates the first definitive link between mutations in the gene DICER1 and cancer. view more (2009-06-26)
UC Davis researchers identify a protein that may help breast cancer spread, beat cancer drugs New research from UC Davis Cancer Center shows that a protein called Muc4 may be the essential ingredient that allows breast cancer to spread to other organs and resist therapeutic treatment. view more (2009-04-02)
Blood-vessel blocker aids cancer-killing virus Cancer-killing viruses are a promising therapy for incurable brain tumors, but their effectiveness has been limited in part because immune cells rapidly move in and eliminate them. view more (2007-11-28)
Discovery about obesity drug helping scientists develop new cancer treatments Based on their surprising discovery that an obesity drug can kill cancer cells, scientists at Wake Forest University School of Medicine have made a new finding about the drug's effects and are working to design more potent cancer treatments. view more (2007-07-09)
Columbia University Medical Center researchers discover potential mechanism for tumor growth Researchers at Columbia University Medical Center have identified an inherent feature of stem and progenitor cells that may promote initiation and progression of cancerous tumors. view more (2005-12-16)
Reversing cancer cells to normal cells In earlier work, Northwestern University scientist Mary J.C. Hendrix and colleagues discovered that aggressive melanoma cells (but not normal skin cells nor less aggressive melanoma cells) contain specific proteins similar to those found in embryonic stem cells. view more (2007-04-30)
First gene associated with myeloproliferative diseases Myelodysplastic / myeloproliferative diseases (MDS/MPD) are blood stem cell disorders characterized by ineffective formation and development of blood cells in the bone marrow, resulting in abnormal development of bone marrow precursor cells and a reduction in the number of blood cells. view more (2005-08-26)
Study identifies another strategy for normalizing tumor blood supply Manipulating levels of nitric oxide (NO), a gas involved in many biological processes, may improve the disorganized network of blood vessels supplying tumors, potentially improving the effectiveness of radiation and chemotherapy. view more (2008-02-21)
Stopping the clock: Genetics of tumor latency in skin cancer Dr. Anthony E. Oro and colleagues (Stanford University) have identified two key Gli protein degradation signals that directly affect tumor latency in a mouse model of human skin cancer. view more (2006-01-20)
New technique detects early metastasis of breast cancer In the U.S., a novel technology soon may be available to detect the spread, or metastasis, of breast cancer earlier than now possible, according to research presented at the first international meeting on Molecular Diagnostics in Cancer Therapeutic Development. view more (2006-09-14)
Marrow-derived stem cells deliver new cytokine to kill brain tumor cells, offer protection Attaching a recently discovered cytokine to neural stem cells derived from bone marrow, researchers at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute have developed a tool to track and kill malignant brain tumor cells and provide long-term protection against their return. view more (2006-03-01)
Drug therapy reduces neuroblastoma tumor growth in pre-clinical investigation Researchers from the Children's Cancer Hospital at The University of Texas M. D. Anderson Cancer Center have discovered a new drug combination that significantly hinders tumor growth in neuroblastoma, a childhood cancer. view more (2009-04-27)
Science researchers genetically transform immune cells into tumor fighters A team of researchers has genetically engineered normal immune cells to become specialized tumor fighters, demonstrating for the first time that these engineered cells can persist in the body and shrink large tumors in humans. view more (2006-09-01)
Cancer-killing viruses influence tumor blood-vessel growth Viruses genetically designed to kill cancer cells offer a promising strategy for treating incurable brain tumors such as glioblastoma, but the body's natural defenses often eliminate the viruses before they can eliminate the tumor. view more (2008-06-11)
Potential diagnostic marker indicates effectiveness of anti-angiogenic drugs If an anti-angiogenic drug is successfully starving a cancer patient's tumor to death, the number of endothelial cells circulating in the individual's bloodstream will decrease, thus providing a potential biomarker for gauging the medication's effectiveness. view more (2006-09-18)
To evade chemotherapy, some cancer cells mimic stem cells Anti-cancer treatments often effectively shrink the size of tumors, but some might have an opposite effect, actually expanding the small population of cancer stem cells believed to drive the disease, according to findings presented today in Atlanta, Georgia at the American Association for Cancer Research's second International Conference on... view more... (2007-09-20)
New Cancer Gene Discovered Researchers at the OU Cancer Institute have identified a new gene that causes cancer. The ground-breaking research appears Monday in Nature's cancer journal Oncogene. view more (2008-05-09)
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