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Researchers urge monitoring of bone health during chemotherapy
In laboratory tests on mice, researchers found that a medication often used to reduce toxic side effects of chemotherapy induced bone loss and helped tumors grow in bone. So the researchers at Washington University School of Medicine in St. Louis are recommending increased awareness of bone health... view more (2007-01-15)

New model of p53 regulation proposed that suggests novel anticancer strategy
Genetically engineered mice convinced scientists at the Salk Institute for Biological Studies that it was time to overhaul widely held beliefs about how a powerful tumor suppressor called p53 is controlled in cells.   view more (2006-04-12)

Childhood brain tumor traced to normal stem cells gone bad
An aggressive childhood brain tumor known as medulloblastoma originates in normal brain "stem" cells that turn malignant when acted on by a known mutant, cancer-causing oncogene, say researchers from Dana-Farber Cancer Institute and the University of California, San Francisco (UCSF).   view more (2008-08-12)

Penn researchers provide insights into how the immune system avoids attacking itself
A finding by University of Pennsylvania School of Medicine researchers about how immune cells "decide" to become active or inactive may have applications in fighting cancerous tumors, autoimmune diseases, and organ transplant rejection.   view more (2006-10-13)

Study raises questions about prostate cancer therapies targeting IGF-1
Therapies under development to treat prostate cancer by inhibiting the ability of insulin-like growth factor (IGF-1) to activate its target receptor could have unexpected results especially if a major tumor suppressor gene - p53 - is already compromised, according to new research by investigators... view more (2008-05-01)

Research suggests new treatment suitable for all patients
New research at Wake Forest University Baptist Medical Center suggests that a three-drug cocktail may one day improve outcomes in patients with glioblastoma multiforme (GBM), a type of brain tumor with a dismal prognosis.   view more (2008-01-02)

Ethanol injection helps manage bone metastasis in thyroid cancer patients
Percutaneous ethanol injection (PEI)-an injection of ethanol (alcohol) through the skin directly into a bone tumor to kill cancer cells-may be a valuable ancillary treatment for thyroid cancer patients whose cancer has spread to the bone. Japanese researchers announced these findings during the... view more (2007-06-04)

MIT engineers an anti-cancer smart bomb
Imagine a cancer drug that can burrow into a tumor, seal the exits and detonate a lethal dose of anti-cancer toxins, all while leaving healthy cells unscathed.   view more (2005-07-28)

Adaptation to oxygen deprivation elucidates tumor physiology
Two new studies in the March Cell Metabolism reveal a survival mechanism by which cells adapt to oxygen starvation by ratcheting down their demand.   view more (2006-03-08)

Barrow researchers identify a new approach to detect the early progression of brain tumors
Researchers at Barrow Neurological Institute at St. Joseph's Hospital and Medical Center recently participated in a pilot study with the Montreal Neurological Institute that suggests a certain type of MRI scanning can detect when a patient is failing brain tumor treatment before symptoms appear.   view more (2008-08-29)

Flip of genetic switch causes cancers in mice to self-destruct, Stanford researchers find
Killing cancerous tumors isn't easy, as anyone who has suffered through chemotherapy can attest. But a new study in mice shows that switching off a single malfunctioning gene can halt the limitless division of tumor cells and turn them back to the path of their own planned obsolescence.   view more (2007-07-31)

Breast Tumors in Mice Eradicated Using Cancer Vaccine
A team from the University of Pennsylvania School of Medicine has shown that by using a cancer vaccine based on the bacterium Listeria monocytogenes, they can cure mice with established breast tumors.   view more (2005-09-15)

Curacyte scientists discover new anti-tumour agents
Curacyte AG, a Munich-based drug development company focused on novel treatments of inflammatory diseases, thrombotic disorders and cancer has announced today that its scientists have discovered a series of novel small molecule inhibitors of matriptase, a trypsin-like serine protease. Matriptase is... view more (2003-06-17)

MRI: A window to genetic properties of brain tumors
Doctors diagnose and prescribe treatment for brain tumors by studying, under a microscope, tumor tissue and cell samples obtained through invasive biopsy or surgery.   view more (2008-03-25)

USC researchers show that molecular markers predict tumor recurrence
Researchers at the University of Southern California (USC) have identified specific molecular markers that may help to predict tumor recurrence in stage II and III colon cancer patients.   view more (2007-06-06)

Botox could help target resistant tumors for treatment
The cosmetic treatment Botox may have a new use as an adjuvant to cancer therapy, providing an open door for chemotherapy and radiation treatments.   view more (2006-02-15)

Study details regulation of vital tumor suppressor gene p53
So vital is the p53 tumor suppressor gene in controlling cancer that its dysfunction is linked to more than half of human cancers.   view more (2007-09-06)

Agent orange chemical, dioxin, attacks the mitochondria to cause cancer, says Penn research team
Researchers with the University of Pennsylvania School of Veterinary Medicine have demonstrated the process by which the cancer-causing chemical dioxin attacks the cellular machinery, disrupts normal cellular function and ultimately promotes tumor progression.   view more (2007-12-18)

Researchers identify ovarian cancer biomarkers
Researchers have identified markers unique to the cells of blood vessels running through ovarian tumors. The finding, while preliminary, could one day improve screening, diagnosis and treatment for this disease.   view more (2007-03-08)

Researchers identify ovarian cancer biomarkers
Researchers have identified markers unique to the cells of blood vessels running through ovarian tumors. The finding, while preliminary, could one day improve screening, diagnosis and treatment for this disease.   view more (2007-03-08)

New pathway could present an intervention point for cancer treatment
A new cellular pathway leads to destruction of a protein that promotes growth of breast, prostate and similar cancers and could provide a new avenue through which to pursue treatment of such diseases.   view more (2006-01-27)

Unusual three-drug combo inhibits growth of aggressive tumors
An experimental anti-cancer regimen combined a diuretic, a Parkinson's disease medication and a drug ordinarily used to reverse the effect of sedatives.   view more (2006-09-08)

Researchers identify new cell targets for preventing growth of breast and other tumors
Researchers at the Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill have discovered new targets for cancer treatment aimed at blocking a key step in tumor progression.   view more (2008-04-24)

Researchers identify new cell targets for preventing growth of breast and other tumors
Researchers at the Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill have discovered new targets for cancer treatment aimed at blocking a key step in tumor progression.   view more (2008-04-24)

Cancer drugs my build and not tear down blood vessels
Scientists have thought that one way to foil a tumor from generating blood vessels to feed its growth - a process called angiogenesis - was by creating drugs aimed at stopping a key vessel growth-promoting protein. But now the opposite seems to be true.   view more (2008-11-10)

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