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Tumor growth and chemo response may be predicted by mathematical model
The aggressiveness of tumors and their susceptibility to chemotherapy may become easier to predict based on a mathematical model developed at The University of Texas Health Science Center at Houston. view more (2009-05-19)
CSHL study shows that some malignant tumors can be shut down after all
Oncologists have had their hands tied because more than half of all human cancers have mutations that disable a protein called p53. view more (2009-11-10)
Skin cancer study uncovers new tumor suppressor gene
National Institutes of Health (NIH) researchers have identified a gene that suppresses tumor growth in melanoma, the deadliest form of skin cancer. view more (2009-03-30)
An AIDS-related virus reveals more ways to cause cancer, Penn researchers find
Researchers at the University of Pennsylvania School of Medicine have shed new light on how Kaposi's Sarcoma-associated Herpes Virus (KSHV) subverts normal cell machinery to cause cancer. view more (2007-10-09)
U-Iowa improves delivery of cancer-fighting molecules
Small interfering RNA (siRNA), a type of genetic material, can block potentially harmful activity in cells, such as tumor cell growth. But delivering siRNA successfully to specific cells without adversely affecting other cells has been challenging. view more (2009-08-28)
Study details regulation of vital tumor suppressor gene p53
So vital is the p53 tumor suppressor gene in controlling cancer that its dysfunction is linked to more than half of human cancers. view more (2007-09-06)
A new significance of LVD and angiogenic MVD is identified in human primary SCRC
Lymphangiogenesis and angiogenesis are critical processes for tumor growth, invasion and metastasis. Angiogenesis has established its role in the development and progression of a variety of malignancies, playing a crucial role in the dissemination of the tumor cells. view more (2008-01-17)
MIT nanoparticles may help detect, treat tumors
A new technique devised by MIT engineers may one day help physicians detect cancerous tumors during early stages of growth. view more (2006-05-02)
Dangerous skin cancer
The German Cancer Society has worked out new guidelines for the diagnosis and treatment of malignant melanoma-a disease with unfavorable prognosis. view more (2008-12-19)
Cell's fight against cancer revealed
If anything in cancer biology can be likened to a cage match, this is it: the battle inside the cell walls between LTag, "The Most Amazing Molecule in the Universe," and p53, "The Guardian of the Genome." view more (2006-09-01)
Bioluminescence imaging used for eye cancer detection
At the moment, doctors rely on biopsy analysis to determine the progression of eye cancer. However, researchers now believe that a new technology, bioluminescence imaging (BLI), will allow doctors to detect tumors earlier and quickly choose a method of treatment that doesn't necessarily involve eye surgery. view more (2009-10-14)
Tumor-targeting viral therapy slows neuroblastoma, malignant peripheral nerve sheath tumors
Researchers in a multi-institutional study led by Cincinnati Children's Hospital Medical Center slowed the growth of two particularly stubborn solid tumor cancers - neuroblastoma and peripheral nerve sheath tumors -without harming healthy tissues by inserting instructions to inhibit tissue growth into an engineered virus. view more (2008-02-15)
Yale scientists show that a microRNA can reduce lung cancer growth
A small RNA molecule, known as let-7 microRNA (miRNA), substantially reduced cancer growth in multiple mouse models of lung cancer, according to work by researchers at Yale University and Asuragen, Inc., published in the journal Cell Cycle. view more (2008-03-24)
Cancer-killing viruses influence tumor blood-vessel growth
Viruses genetically designed to kill cancer cells offer a promising strategy for treating incurable brain tumors such as glioblastoma, but the body's natural defenses often eliminate the viruses before they can eliminate the tumor. view more (2008-06-11)
Study demonstrates how gene variant may contribute to cancer development
A relatively common cancer susceptibility gene appears to be frequently acquired in metastatic lesions from colorectal cancer, and give cancer cells a growth advantage, according to a study in the October 5 issue of JAMA. view more (2005-10-05)
MIT implant measures tumor growth, treatment
A tiny implant now being developed at MIT could one day help doctors rapidly monitor the growth of tumors and the progress of chemotherapy in cancer patients. view more (2006-12-19)
A new chemotherapeutic target for hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a major health problem worldwide. Currently, the only chance for obtaining a cure in patients with HCC is by either a surgical resection or liver transplantation. view more (2007-10-25)
Antitumor agent under the microscope
Mechanical stabilization of DNA keeps tumor cells in check Cisplatin is one of the most widely employed cancer medications. As with many other chemotherapy agents, the mechanism by which it works has not been fully researched. Now, thanks to Munich physicists Hermann E. Gaub, Rupert Krautbauer, and Hauke Clausen-Schaumann, an important step toward... view more... (2000-10-30)
A novel mechanism of action for anti-tumor agent, CA4P
Anti-angiogenic agents have been successful in the clinic for blocking the growth of solid tumors. However, these agents used in combination with chemotherapy have improved the survival of patients with cancers by only several months. view more (2005-10-07)
Preclinical study shows chronic stress agitates ovarian cancer; reducing stress slows tumor growth
When mice with ovarian cancer are stressed, their tumors grow and spread more quickly, but that effect can be blocked using a medication commonly prescribed for heart disease. view more (2006-07-24)
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