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An effective target of biological therapy for hepatocellular carcinoma It has been shown that constitutively activated STAT3 is detected in many HCC cell lines and tissues. This suggests that STAT3 is a promising molecular target for HCC gene therapy. view more (2009-06-15)
Targeting the protein AEG1 impairs human liver cancer growth in mice Hepatocellular carcinoma (HCC) is a highly aggressive form of liver cancer and one of the 5 most common cancers worldwide. Devanand Sarkar and colleagues, at Virginia Commonwealth University School of Medicine, Richmond, have now identified a gene that is expressed at high levels in human HCC tumor samples and generates a protein important for HCC... view more... (2009-02-17)
Blue light used to harden tooth fillings stunts tumor growth A blue curing light used to harden dental fillings also may stunt tumor growth, Medical College of Georgia researchers say. view more (2008-06-25)
Estrogen-Dependent Switch Tempers Killing Activity of Immune Cells The sex hormone estrogen tempers the killing activity of a specific group of immune cells, the cytotoxic T cells (CTLs), which are known to attack tumor cells and cells infected by viruses. view more (2009-08-10)
New target for cancer therapy may improve treatment for solid tumors Targeting and killing the non-malignant cells that surround and support a cancer can stop tumor growth in mice, reports a research team based at the University of Chicago Medical Center in the March 1, 2008, issue of the journal Cancer Research. The discovery offers a new approach to treating cancers that are resistant to standard therapy. view more (2008-03-04)
Drug therapy reduces neuroblastoma tumor growth in pre-clinical investigation Researchers from the Children's Cancer Hospital at The University of Texas M. D. Anderson Cancer Center have discovered a new drug combination that significantly hinders tumor growth in neuroblastoma, a childhood cancer. view more (2009-04-27)
Blood protein may hold key to stopping tumor growth in cancer patients A recent discovery by researchers at Wake Forest University School of Medicine could clear the way for a new drug that inhibits tumor growth in cancer patients and could potentially help in the healing of wounds. view more (2009-04-01)
Tissue rigidity promotes tumor progression Most investigations into cancer have focused on chemical signals, but a new research study provides rare insight into how mechanical force can regulate cellular behavior. view more (2005-09-20)
There goes the neighborhood: Vascular niche nurtures brain tumor stem cells Self-renewing cancer stem cells (CSCs) comprise only a tiny fraction of most brain tumors, but eliminating them is likely to have a profound impact on the ability of a tumor to survive and grow. view more (2007-01-17)
Genes that both extend life and protect against cancer identified A person is 100 times more likely to get cancer at age 65 than at age 35. But new research reported today in the journal "Nature Genetics" identifies naturally occurring processes that allow many genes to both slow aging and protect against cancer in the much-studied C. elegans roundworm. view more (2007-10-15)
How does Fu-Zheng-Jie-Du-Decoction act on PTEN expression in hepatocellular carcinoma? Many hepatocellular carcinoma (HCC) patients in China may be treated with Traditional Chinese medicine (TCM). Some say it works, others doubt its effectiveness. These stated that a research group in China had found TCM can down-regulate the expression of PTEN in HCC, which may suppress tumor cell growth and regulate tumor cell invasion and... view more... (2008-01-17)
Cancer stem cells spur glioma Angiogenesis, could hold key to brain tumor therapy Stem cell-like glioma cancer cells that share many characteristics with normal stem cells propel the lethal growth of brain cancers by promoting tumor blood vessel formation, and may hold the key to treating these deadly cancers. view more (2006-08-15)
LSUHSC research may benefit diabetes by increasing understanding of how to control islet cell growth Michael Lan, PhD, Professor of Pediatrics and Genetics at LSU Health Sciences Center New Orleans, is the senior author of a paper revealing the molecular mechanism of how a protein determines the fate of the cells that make and release insulin. view more (2009-02-18)
Cancer stem cells: know thine enemy Stem cells -- popularly known as a source of biological rejuvenation -- may play harmful roles in the body, specifically in the growth and spread of cancer. view more (2007-12-26)
Finding protection from tumor growth in unexpected places Researchers have discovered that an enzyme commonly involved in regulating blood pressure also provides protection from tumor growth when strongly expressed in immune cells. view more (2007-06-06)
New pathway could present an intervention point for cancer treatment A new cellular pathway leads to destruction of a protein that promotes growth of breast, prostate and similar cancers and could provide a new avenue through which to pursue treatment of such diseases. view more (2006-01-27)
RNA splicing factor implicated in ovarian tumor cell growth An RNA-binding protein that is overproduced in ovarian cancer may present a new target for diagnosis or treatment of ovarian and other cancers, according to researchers at the University of Illinois at Chicago. view more (2007-04-10)
Viral oncoprotein inactivation of p53 A group of scientists led by USC researcher Dr. Xiaojiang Chen lend structural insight into tumor suppressor inactivation by a viral oncoprotein. view more (2006-09-01)
Combination therapy reduces tumor resistance to radiation Radiation is used to treat a variety of tumors and the response of tumors to radiation is dependent on endothelial cell death, which in turn limits oxygen delivery to the tumor, causing hypoxia and tumor cell death. view more (2007-06-08)
Obesity drug helps unlock clues about cancer An approved drug for fighting obesity is helping scientists at Wake Forest University School of Medicine uncover clues about how to stop the growth of cancerous tumors. view more (2007-02-02)
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