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USC researchers discover breast cancer stem cells in bone marrow
Almost all tumor cells found in the bone marrow of early stage breast cancer patients appear to be breast cancer stem cells, suggesting the risk of disease spread for all breast cancer patients may be greater than previously thought.   view more (2006-10-09)

UC Davis researchers use heated nanoprobes to destroy breast cancer cells in mice
In experiments with laboratory mice that bear aggressive human breast cancers, UC Davis researchers have used hot nanoprobes to slow the growth of tumors — without damage to surrounding healthy tissue. The researchers describe their work in the March issue of the Journal of Nuclear Medicine.   view more (2007-03-07)

USC researchers show that molecular markers predict tumor recurrence
Researchers at the University of Southern California (USC) have identified specific molecular markers that may help to predict tumor recurrence in stage II and III colon cancer patients.   view more (2007-06-06)

Allergy drug slows pancreatic tumor growth in preclinical studies
An anti-allergy drug in use for more than 40 years significantly reduced tumor growth in animal models of human pancreatic cancer and also increased the effectiveness of standard chemotherapy.   view more (2006-12-20)

MIT IDs link between brain tumor proteins
MIT researchers have identified a critical link between two proteins found in brain tumors, a discovery that could eventually help treat a form of brain cancer that kills 99 percent of patients.   view more (2007-07-20)

Scripps research scientists show protein accelerates breast cancer progression in animal models
These new findings could lead to a better understanding of the molecular pathogenesis of breast cancer and focus attention on PTN and its signaling pathway as possible targets for new cancer therapies.   view more (2007-06-21)

Jefferson scientists find tumor suppressor gene protects against pre-cancerous development
Cell biologists at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia have provided further evidence that a gene thought to play a role in suppressing tumors actually can protect against the development of pre-cancerous cell growth as well.   view more (2006-11-02)

MRI: A window to genetic properties of brain tumors
Doctors diagnose and prescribe treatment for brain tumors by studying, under a microscope, tumor tissue and cell samples obtained through invasive biopsy or surgery.   view more (2008-03-25)

Therapeutic peptide frees the protein p73 to kill tumor cells
The protein p53 suppresses tumor development by potently inducing tumor cell death, making it an obvious target for anticancer therapeutics.   view more (2007-03-09)

BC biologists identify alternative brain cancer treatment
Boston College biologists have identified an alternative, diet-based method of treating brain cancer that does not involve administering toxic chemicals, radiation or invasive surgery.   view more (2007-02-21)

Novel model of osteosarcoma
In the June 15th issue of G&D, Dr. Stuart Orkin (HHMI, Dana-Farber Cancer Institute, Children's Hospital Boston) and colleagues present a new mouse model of osteosarcoma.   view more (2008-06-16)

tNOX serves as a serum marker for detection and monitoring of disease progression in prostate cancer
A team of researchers at Purdue University has found a protein in the blood that may prove to be more reliable than the standard prostate specific antigen (PSA) test in measuring the extent of prostate cancer.   view more (2006-09-14)

FDG-PET accurate for evaluating lung tumor destruction from radiofrequency ablation
FDG-PET can be used to assess the amount of tumor destruction after radiofrequency ablation (RFA)-the use of heat to destroy tumors-for the treatment of lung tumors and may provide more valuable information than CT alone, according to a new study.   view more (2006-05-01)

A stem cell type supposed to be crucial for angiogenesis and cancer growth does not exist?
Angiogenesis, the growth of new blood vessels, is a central process in diverse physiological and pathological situations such as healing of wounds and traumas, cardiovascular disorders, inflammatory conditions such as rheumatoid arthritis, and in cancer growth.   view more (2008-04-23)

New targeted treatment for brain tumors shows promise in pre-clinical models
Monoclonal antibody targets key tumor growth factor; Successfully causes brain tumor regression and improves animal survival.   view more (2006-02-15)

Does natural selection drive the evolution of cancer?
The dynamics of evolution are fully in play within the environment of a tumor, just as they are in forests and meadows, oceans and streams. This is the view of researchers in an emerging cross-disciplinary field that brings the thinking of ecologists and evolutionary biologists to bear on cancer... view more (2006-11-20)

Researchers identify new cell targets for preventing growth of breast and other tumors
Researchers at the Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill have discovered new targets for cancer treatment aimed at blocking a key step in tumor progression.   view more (2008-04-24)

Researchers identify new cell targets for preventing growth of breast and other tumors
Researchers at the Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill have discovered new targets for cancer treatment aimed at blocking a key step in tumor progression.   view more (2008-04-24)

Tulane pioneers novel ovarian cancer treatment
The Tulane University Section of Hematology and Medical Oncology is investigating a novel treatment for ovarian cancer by using intravenous Ontak to deplete harmful cells that inhibit the body's natural immune response to fight cancer. Ovarian cancer is the fifth leading cancer killer of women in... view more (2005-07-18)

New animal study may explain why alcohol consumption increases breast cancer risk
For the first time, scientists have used a laboratory mouse model to mimic the development of human alcohol-induced breast cancer.   view more (2007-04-30)

Cancer-causing protein may heal damaged spinal cord and brain cells
Cancer researchers at Columbia University Medical Center have found that a protein known for driving the growth of cancer also plays a surprising role in restoring the ability of neurons to regenerate, making it an important target for addressing spinal cord damage or neurological diseases like... view more (2006-06-29)

New approach to gene therapy may shrink brain tumors, prevent their spread
Massachusetts General Hospital (MGH) researchers are investigating a new approach to gene therapy for brain tumors - delivering a cancer-fighting gene to normal brain tissue around the tumor to keep it from spreading.   view more (2008-09-26)

Brain tumor researchers find their 'niche'
Brain tumors appear to arise from cancer stem cells (CSCs) that live within microscopic protective "niches" formed by blood vessels in the brain; and disrupting these niches is a promising strategy for eliminating the tumors and preventing them from re-growing.   view more (2007-01-17)

Unique estrogen receptor linked to metastatic breast cancer
Breast cancer awareness month may have passed, but researchers remain focused on the disease with a new study showing that a unique estrogen receptor found in breast cancer tumors is a predictor of tumor size and metastases.   view more (2006-11-01)

Cancer therapy: A role for MAPK inhibitors combined with mTORC1 inhibitors
Nearly a decade ago, while it was being tested as an immunosuppressive agent to prevent organ rejection in transplant patients, the drug rapamycin was also discovered to have anti-tumor properties. Since then, several rapamycin analogs known as mTOR (mammalian target of rapamycin) inhibitors have... view more (2008-08-22)
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