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Small molecule derived from Rb2/p130 could act as cancer therapeutic
A small molecule derived from the spacer domain of the tumor-suppressor gene Rb2/p130 has demonstrated the ability to inhibit tumor growth in vivo and could be developed into an anti-cancer therapeutic, according to researchers at Temple University's Sbarro Institute for Cancer Research and Molecular Medicine.   view more (2007-03-21)

St. Jude study shows temporary improvement of tumor blood flow can improve chemotherapy
A treatment for neuroblastoma that lands a one-two punch works best when the second punch is timed to take maximum advantage of the first one, according to results of studies at St. Jude Children's Research Hospital.   view more (2007-07-12)

SIRT1 takes down tumors
Yuan et al. have identified another anti-cancer effect of the "longevity" protein SIRT1. By speeding the destruction of the tumor promoter c-Myc, SIRT1 curbs cell division.   view more (2009-04-13)

Killing Cancer Like a Vampire Slayer
Like vampires, cancer tumors require an ample supply of blood to stay alive. Without fresh blood for sustenance, cancer cells shrivel up like raisins and die.   view more (2009-09-18)

Mesothelin engineered on virus-like particles provides treatment clues for pancreatic cancer
New understanding of a protein that spurs the growth of pancreatic cancer could lead to a new vaccine against the deadly disease, said researchers at Baylor College of Medicine in Houston in a report appearing in the current edition of the journal Molecular Cancer Therapeutics.   view more (2008-02-15)

Gene signature helps predict breast cancer prognosis
Vanderbilt-Ingram Cancer Center researchers have uncovered a gene signature that may help predict clinical outcomes in certain types of breast cancer.   view more (2009-05-20)

Inhibitor of novel cancer target, LPAAT-beta, demonstrates selective anti-cancer effects in animal cancer models
Frankfurt, Germany: In a plenary session at the Symposium on Molecular Targets and Cancer Therapeutics, Dr Jack W. Singer, M.D. and Research Program Chairman of Cell Therapeutics, Inc. (CTI) today (Thursday 21 November) presented data from preclinical studies on a novel cancer target LPAAT-beta[1] in cultured cells and in preliminary animal... view more... (2002-11-17)

Computer Model Predicts Brain Tumor Growth and Evolution
Researchers from Brown University and other institutions have developed a computational computer model of how brain tumors grow and evolve.   view more (2009-05-19)

Angiogenesis inhibitor improves brain tumor survival by reducing edema
The beneficial effects of anti-angiogenesis drugs in the treatment of the deadly brain tumors called glioblastomas appear to result primarily from reduction of edema - the swelling of brain tissue - and not from any direct anti-tumor effect.   view more (2009-03-30)

Enhanced DNA-repair mechanism can cause breast cancer
Although defects in the "breast cancer gene," BRCA1, have been known for years to increase the risk for breast cancer, exactly how it can lead to tumor growth has remained a mystery.   view more (2007-10-15)

A genetic factor predicts prognosis in brain tumor patients
PLoS ONE has just published a study which defines a gene locus on chromosome 1 that predicts prognosis of brain tumor patients and may even set the basis for the development of more efficient drugs to combat brain cancer.   view more (2007-06-28)

Signal protein shows promise for blocking tumor promoters in skin cells
A protein with the ironic name "Srcasm" can counteract the effects of tumor-promoting molecules in skin cells, according to new research by investigators at the University of Pennsylvania School of Medicine.   view more (2006-11-06)

A new measure for the malignancy of melanoma
Every tumor, starting from a size of a few millimeters, depends on a supply of nutrients and oxygen. Therefore, using special growth factors, it induces vascular wall cells of neighboring blood vessels to sprout new capillaries in order to get connected to the blood circulation.   view more (2009-03-12)

Nanoparticles carry chemotherapy drug deeper into solid tumors
A new drug delivery method using nano-sized molecules to carry the chemotherapy drug doxorubicin to tumors improves the effectiveness of the drug in mice and increases their survival time.   view more (2007-06-27)

UCSD researchers discover variants of natural tumor suppressor
Building on their 2005 discovery of an enzyme that is a natural tumor suppressor, researchers at the University of California, San Diego (UCSD) School of Medicine have now identified two variants of that enzyme which could provide new targets for therapies to treat diabetes, heart and neurological disease.   view more (2007-04-10)

Bevacizumab found to improve survival for patients with advanced breast cancer
Inhibiting the growth of blood vessels that supply tumors slows the progression of metastatic breast cancer according to results of a large clinical trial of Avastin, an anti-angiogenic therapy.   view more (2007-12-27)

UCLA study shows altering fatty acid levels in diet may reduce prostate cancer growth rate
UCLA researchers found that altering the fatty acid ratio found in the typical Western diet to include more omega-3 fatty acids and decrease the amount of omega-6 fatty acids may reduce prostate cancer tumor growth rates and PSA levels.   view more (2006-08-01)

Targeting the more lethal form of the cancer rhabdomyosarcoma
Rhabdomyosarcoma (RMS) is an aggressive muscle cancer that mostly affects children. The most common forms of RMS are embryonal rhabdomyosarcoma (ERMS) and alveolar rhabdomyosarcoma (ARMS).   view more (2009-05-26)

Fruit fly protein acts as decoy to capture tumor growth factors, find Penn researchers
Researchers at the University of Pennsylvania School of Medicine have shown how Argos, a fruit fly protein, acts as a ¡¥decoy' receptor, binding growth factors that promote the progression of cancer.   view more (2008-05-29)

USC researchers develop new drug to target tumor cells and blood vessels
Researchers at the University of Southern California have identified a new drug compound that appears to target tumor cells and surrounding blood vessels without the negative side effects typically associated with Cox-2 inhibitors.   view more (2009-04-20)
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