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Massive necrosis after trans-catheter treatment is more common in the presence of tumor capsule
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Prognosis of patients with HCC complicating cirrhosis mainly depends on the tumor growth, progression of the underlying liver disease and the effectiveness of antitumoral treatment. view more (2007-11-26)
Growth factor signals influence balance between normal growth and cancerous growth
New research from The Children's Hospital of Philadelphia and the University of Pennsylvania School of Medicine deepens the understanding of how the growth hormone/IGF system is affected by another important actor: p53, the tumor suppressor gene that puts the brakes on cancer. view more (2006-11-10)
Two suppressor molecules affect 70 genes in leukemia
By restoring two small molecules that are often lost in chronic leukemia, researchers were able to block tumor growth in an animal model. view more (2008-04-25)
Study identifies characteristics of fast-growing skin cancers
Melanomas (skin cancers) are more likely to grow rapidly if they are thicker, symmetrical, elevated, have regular borders or have symptoms, according to a report in the December issue of Archives of Dermatology, one of the JAMA/Archives journals. view more (2006-12-19)
USC stem cell study sheds new light on cell mechanism
Research from the University of Southern California (USC) has discovered a new mechanism to allow embryonic stem cells to divide indefinitely and remain undifferentiated. view more (2008-05-22)
T-beta-RIII joins the fight against breast cancer
Although the soluble factor TGF-beta has been shown to suppress the growth of tumor cells in the early stages of breast cancer, high levels of TGF-beta during the later stages of the disease are associated with a poor outcome. view more (2006-12-08)
Role of autophagy in tumorigenesis
In the June 1 issue of G&D, Dr. Eileen White and colleagues at Rutgers University/University of Medicine and Dentistry of New Jersey/Cancer Institute of New Jersey, report, for the first time, that the cellular self-digesting process of autophagy can protect genome integrity - lending new insight into the seemingly contradictory roles of... view more... (2007-05-18)
UC Davis researchers use heated nanoprobes to destroy breast cancer cells in mice
In experiments with laboratory mice that bear aggressive human breast cancers, UC Davis researchers have used hot nanoprobes to slow the growth of tumors — without damage to surrounding healthy tissue. The researchers describe their work in the March issue of the Journal of Nuclear Medicine. view more (2007-03-07)
U-M researchers link pathway to breast cancer stem cells
A gene well known to stop or suppress cancer plays a role in cancer stem cells, according to a new study from the University of Michigan Comprehensive Cancer Center. The researchers found that several pathways linked to the gene, called PTEN, also affected the growth of breast cancer stem cells. view more (2009-06-02)
USC researchers discover breast cancer stem cells in bone marrow
Almost all tumor cells found in the bone marrow of early stage breast cancer patients appear to be breast cancer stem cells, suggesting the risk of disease spread for all breast cancer patients may be greater than previously thought. view more (2006-10-09)
Allergy drug slows pancreatic tumor growth in preclinical studies
An anti-allergy drug in use for more than 40 years significantly reduced tumor growth in animal models of human pancreatic cancer and also increased the effectiveness of standard chemotherapy. view more (2006-12-20)
Scripps research scientists show protein accelerates breast cancer progression in animal models
These new findings could lead to a better understanding of the molecular pathogenesis of breast cancer and focus attention on PTN and its signaling pathway as possible targets for new cancer therapies. view more (2007-06-21)
USC researchers show that molecular markers predict tumor recurrence
Researchers at the University of Southern California (USC) have identified specific molecular markers that may help to predict tumor recurrence in stage II and III colon cancer patients. view more (2007-06-06)
MIT IDs link between brain tumor proteins
MIT researchers have identified a critical link between two proteins found in brain tumors, a discovery that could eventually help treat a form of brain cancer that kills 99 percent of patients. view more (2007-07-20)
Jefferson scientists find tumor suppressor gene protects against pre-cancerous development
Cell biologists at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia have provided further evidence that a gene thought to play a role in suppressing tumors actually can protect against the development of pre-cancerous cell growth as well. view more (2006-11-02)
MRI: A window to genetic properties of brain tumors
Doctors diagnose and prescribe treatment for brain tumors by studying, under a microscope, tumor tissue and cell samples obtained through invasive biopsy or surgery. view more (2008-03-25)
BC biologists identify alternative brain cancer treatment
Boston College biologists have identified an alternative, diet-based method of treating brain cancer that does not involve administering toxic chemicals, radiation or invasive surgery. view more (2007-02-21)
Novel model of osteosarcoma
In the June 15th issue of G&D, Dr. Stuart Orkin (HHMI, Dana-Farber Cancer Institute, Children's Hospital Boston) and colleagues present a new mouse model of osteosarcoma. view more (2008-06-16)
Cell Biologists Identify New Tumor Suppressor for Lung Cancer
Cancer and cell biology experts at the University of Cincinnati (UC) have identified a new tumor suppressor that may help scientists develop more targeted drug therapies to combat lung cancer. view more (2009-01-06)
Researchers identify new anti-tumor gene
Researchers from Virginia Commonwealth University have identified a new anti-tumor gene called SARI that can interact with and suppress a key protein that is overexpressed in 90 percent of human cancers. The discovery could one day lead to an effective gene therapy for cancer. view more (2008-12-17)
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