Tumor Suppressor Current Events | Tumor Suppressor News | 6
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Research uncovers clues to virus-cancer link
In a series of recently-published articles, a research team from the University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center has uncovered clues to the development of cancers in AIDS patients. view more (2009-06-18)
Mayo Clinic Researchers Find That Protein Believed to Protect Against Cancer Has a Mr. Hyde Side
In a biological rendition of fiction's Strange Case of Dr. Jekyll and Mr. Hyde, researchers from the Mayo Clinic campus in Florida and Harvard Medical School have found that a protein thought to protect against cancer development can actually spur the spread of tumors. view more (2009-09-04)
Targeting the protein AEG1 impairs human liver cancer growth in mice
Hepatocellular carcinoma (HCC) is a highly aggressive form of liver cancer and one of the 5 most common cancers worldwide. Devanand Sarkar and colleagues, at Virginia Commonwealth University School of Medicine, Richmond, have now identified a gene that is expressed at high levels in human HCC tumor samples and generates a protein important for HCC... view more... (2009-02-17)
Salk researchers develop novel glioblastoma mouse model
Researchers at the Salk Institute for Biological Studies have developed a versatile mouse model of glioblastoma-the most common and deadly brain cancer in humans-that closely resembles the development and progression of human brain tumors that arise naturally. view more (2009-01-05)
Stowers scientists clarify role of tumor suppressor gene
Jiwang Zhang, Ph.D., formerly a Senior Research Associate at the Stowers Institute for Medical Research, and Linheng Li, Ph.D., Associate Investigator, are credited as the first and last authors, respectively, on a paper highlighting several previously unknown functions of phosphatase and tensin homolog (PTEN), an important tumor suppressor gene. view more (2006-04-24)
Therapeutic peptide frees the protein p73 to kill tumor cells
The protein p53 suppresses tumor development by potently inducing tumor cell death, making it an obvious target for anticancer therapeutics. view more (2007-03-09)
Test helps identify patients with breast cancer who will likely benefit from chemotherapy
A test that measures the amounts of two members of the same protein family-one of which appears to act as an oncogene, and the other as a tumor suppressor-helps identify patients with breast cancer who will likely benefit from chemotherapy and those who won't, according to researchers. view more (2006-09-18)
FDG-PET accurate for evaluating lung tumor destruction from radiofrequency ablation
FDG-PET can be used to assess the amount of tumor destruction after radiofrequency ablation (RFA)-the use of heat to destroy tumors-for the treatment of lung tumors and may provide more valuable information than CT alone, according to a new study. view more (2006-05-01)
Arsenic-based therapy shown to help eradicate leukemia-initiating cells
In both leukemia and solid tumors, there exists among the multitude of warrior cancer cells a small subgroup that work undercover, patiently lying in wait to launch their attacks. view more (2008-05-13)
Process controlling T cell growth and production identified
Identifying one of the processes that plays a role in naļve and memory T-cells' growth and production could one day lead to better vaccines and possibly more effective cancer immunotherapy. view more (2009-05-04)
Barrow study identifies new way to biopsy brain tumors in real time
A new miniature, hand-held microscope may allow more precise removal of brain tumors and an easier recognition of tumor locations during surgery. view more (2009-11-12)
Defects in critical gene lead to accelerated lung tumor growth
Cancer causing mutations occur in our bodies every day - but luckily, we have specific genes that recognize these malignant events and keep cells from growing out of control. Only a few of these genes - called tumor suppressors - are currently known. view more (2007-08-06)
SEK 20 million for brain tumor research
The M'¤rit and Hans Rausing Charitable Foundation in England has awarded SEK 20 million over five years to a research team at the Faculty of Medicine at Lund University in Sweden. The team is conducting the so-called BRIGTT Project (BRain Immuno Gene Tumor Therapy), which is pursuing laboratory work and clinical research to try to find new methods... view more... (2003-06-25)
Early stage colon cancer characterized by inactivation of gatekeeper gene
The absence or inactivation of the RUNX3 gatekeeper gene paves the way for the growth and development of colon cancer, Singapore scientists report in the Sept. issue of the journal Cancer Cell. Previous studies have shown that RUNX3 plays a role in gastric, breast, lung and bladder cancers. view more (2008-09-10)
Head and neck cancer vaccine targets proteins to create immune response
Most attempts to create therapeutic cancer vaccines are based on custom-made approaches that use a patient's own tumor cells to generate a strong immune response against cancer. However, developing these kinds of personalized vaccines is time-consuming, expensive and often impractical. view more (2007-04-18)
Novel genetic screens provide panoramic views of cellular systems
Despite the rise of systems biology, many geneticists continue to probe genes in isolation. They even use cutting-edge RNA interference (RNAi) technology to knock down one gene at a time. This approach often yields a narrow view of cellular systems. view more (2008-10-17)
Research shows cell's inactive state is critical for effectiveness of cancer treatment
A new study sheds light on a little understood biological process called quiescence, which enables blood-forming stem cells to exist in a dormant or inactive state in which they are not growing or dividing. view more (2009-01-12)
Colorful spy tactics track live cells supporting cancerous tumors
A new advance in cellular imaging is allowing scientists to better understand the movement of cells in the area around tumors, also known as the tumor microenvironment. view more (2008-09-17)
UT Southwestern researchers find marker for severity in adult brain cancer
Researchers at UT Southwestern Medical Center have identified a new biological indicator that may help identify which brain-cancer patients have the most aggressive forms of the disease. view more (2009-04-01)
Jefferson scientists find tumor suppressor gene protects against pre-cancerous development
Cell biologists at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia have provided further evidence that a gene thought to play a role in suppressing tumors actually can protect against the development of pre-cancerous cell growth as well. view more (2006-11-02)
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