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Tumor Suppressor Current Events | Tumor Suppressor News | 7

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Identifying the potential for tamoxifen resistance in patients
Tamoxifen is a widely used and highly successful drug in the treatment of breast cancer, though resistance to tamoxifen is still a concern in recurrent disease (affecting 25-35% of patients), since therapy resistant metastatic tumor cells are a major cause of death.   view more (2009-06-11)

Bits of 'junk' RNA aid master tumor-suppressor gene
Little-known bits of RNA help master tumor-suppressor gene do its job, U-M cancer researchers find. Three micro RNA genes appear to be key partners of protective gene p53; their loss is linked to common type of lung cancer.   view more (2007-08-24)

A new mathematical formula for cancer progression
Tumor progression can now be mapped less to mathematical standards and more to individual patients according to a new study by researchers at Harvard and Johns Hopkins Universities.   view more (2007-11-09)

Roles of S100A2 and p63 in the carcinogenesis of esophageal squamous cell carcinoma
As a member of the S100 family, S100A2 is considered a candidate tumor-suppressor gene. Recently, p63 gene, a new member of the p53 gene family, has been studied in the fields of tumorigenesis, cell apoptosis and tissue growth.   view more (2009-09-17)

Dangerous skin cancer
The German Cancer Society has worked out new guidelines for the diagnosis and treatment of malignant melanoma-a disease with unfavorable prognosis.   view more (2008-12-19)

Popular herbal supplement hinders the growth of pancreatic cancer cells
A new study from the University of Pittsburgh Cancer Institute suggests that a commonly used herbal supplement, triphala, has cancer-fighting properties that prevent or slow the growth of pancreatic cancer tumors implanted in mice.   view more (2007-04-18)

Enhancement of pancreatic cancer on dynamic CT: Does it correlate with angiogenesis and fibrosis?
Prognosis of pancreatic cancer is poor. Recently, it has been clarified that the grade of tumor angiogenesis is a useful prognostic marker in human cancer, including pancreatic cancer.   view more (2009-07-16)

Novel regulatory mechanism identified for key tumor suppressor p53
Collaborating scientists from The Wistar Institute in Philadelphia and The Vienna Biocenter in Austria have identified a novel mechanism involved in normal repression of the p53 protein, perhaps the single most important molecule for the control of cancer in humans.   view more (2006-11-16)

Testicular cancer gauge often not used
A standard part of testicular cancer care isn't used in more than half of all patients who have the condition, researchers at the University of Michigan Comprehensive Cancer Center have found.   view more (2008-03-18)

Stabilizing cancer-fighting p53 can also shield a metastasis-promoter
Efforts to protect the tumor-suppressor p53 could just as easily shelter a mutant version of the protein, causing cancer cells to thrive and spread rather than die, according to research by scientists at The University of Texas M. D. Anderson Cancer Center reported in the current issue of the journal Genes and Development.   view more (2008-05-23)

'Erectile dysfunction' drugs heighten natural anti-cancer activity
Sildenafil and other "impotence drugs" that boost the production of a gassy chemical messenger to dilate blood vessels and produce an erection now also show promise in unmasking cancer cells so that the immune system can recognize and attack them, say scientists at the Johns Hopkins Kimmel Cancer Center.   view more (2006-12-08)

Vet medicine researcher examines link between cancer, Down syndrome
here's new hope for breast cancer research, and it's coming from a very unlikely place. Researchers at the Texas A&M University College of Veterinary Medicine & Biomedical Sciences recently published articles in the journals Molecular and Cellular Biology and Carcinogenesis indicating that a protein long suspected to play a role in Down... view more... (2008-02-05)

Fluorescent cancer cells to guide brain surgeons
Gliomas are malignant brain tumors that arise from glial (supporting) cells of the brain. Gliomas are often resistant to chemotherapy.   view more (2009-04-06)

Gene therapy increases survival for end-stage head and neck cancer
A gene therapy invented at The University of Texas M. D. Anderson Cancer Center is the first to succeed in a U.S. phase III clinical trial for cancer, as announced today at the American Society of Gene Therapy annual meeting in Boston.   view more (2008-05-29)

Protein marker associated with positive outcome in invasive breast cancer
Researchers at Sunnybrook and Women's College Health Sciences Centre have found a new protein marker linked to positive outcome in patients with breast cancer.   view more (2005-11-16)

Promising new methods of treatment for fatal abdominal tumor
GIST is a soft-parts tumor that occurs in the abdomen but is distinguishable from gastro-intestinal cancer. Previously, surgery has been the only treatment option since this type of tumor does not respond to either chemotherapy or radiation. Scientists at the Sahlgrenska Academy at Göteborg University have now shown that the prognosis for... view more... (2003-03-17)

Tiny tool to control growing blood vessels opens new potential in tumor research
Researchers at Uppsala University have developed a new tool that makes it possible to study the signals in the body that control the generation of blood vessels.   view more (2009-02-23)

Regulatory molecule for tumor formation or suppression identified by Singapore, US researchers
One of the small regulatory molecules, named microRNA-125b, is a novel regulator of p53, an important protein that safeguards cells against cancers, Singapore and U.S. scientists report in the March 17, 2009 issue of the journal Genes & Development.   view more (2009-03-18)

New brain tumor model developed
A collaboration of researchers, led by Dr. Martine Roussel (St. Jude Children's Research Hospital), has developed a novel mouse model of medulloblastoma - the most prevalent malignant pediatric brain tumor.   view more (2005-10-31)

7 years without a nose
Patients whose nose has been destroyed by a tumor or injury carry a severe psychological and social burden. Esthetic reconstruction ranges among the most challenging tasks in plastic surgery.   view more (2008-11-07)
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