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The future of personalized cancer treatment: An entirely new direction for RNAi delivery
In technology that promises to one day allow drug delivery to be tailored to an individual patient and a particular cancer tumor, researchers at the University of California, San Diego School of Medicine, have developed an efficient system for delivering siRNA into primary cells. view more (2009-05-18)
miR-196a promotes the metastases of tumors
MicroRNAs are small RNA molecules of 20-25 nucleotides length, regulating gene expression by inhibition of transcription or translation of proteins. view more (2009-05-13)
Researchers witness natural selection at work in dramatic comeback of male butterflies
An international team of researchers has documented a remarkable example of natural selection in a tropical butterfly species that fought back - genetically speaking - against a highly invasive, male-killing bacteria. view more (2007-07-13)
Mathematics reveals genetic pattern of tumor growth
Using mathematical theory, UC Irvine scientists have shed light on one of cancer's most troubling puzzles - how cancer cells can alter their own genetic makeup to accelerate tumor growth. view more (2007-06-25)
Colon Cancer : An alternative pathway of tumor development
Cancer develops from a single damaged cell subsequent to an accumulation of genetic errors in a number of its genes. The nature of these alterations and the order in which they occur differ from one cancer to another : hence, the "pathways" that may lead to cancer are numerous. CNRS and INSERM researchers at the Institut Curie have just... view more... (2002-09-13)
Enhanced skin cancer risk linked to defects in cellular aging controls
Cell lifespan is limited by telomeres, DNA sequences that cap chromosomes and control the number of times a cell may be copied. A new study reported in Disease Models & Mechanisms (DMM), dmm.biologists.org, describes how telomere dysfunction in skin cells can lead to increased skin cancer risk and pigmentation. view more (2009-02-23)
Scientists develop a novel strategy to help prevent transplant rejection
A study led by Imperial College London has shown for the first time it is possible to help prevent organ rejection using a novel strategy that redirects the body's immune response instead of suppressing it. Writing in the Journal of Clinical Investigation today, researchers from the University of Cambridge, the University of Edinburgh, Lorantis... view more... (2003-12-03)
Mutation in tumor suppressor gene causes pancreatic islet cells to reproduce
Researchers at the University of Pennsylvania School of Medicine have found that the acute loss of a protein called menin can cause the proliferation of pancreatic islet cells, which secrete insulin to regulate blood sugar. view more (2006-07-06)
A new theoretical model of tumor growth and metastasis based on differences in tissue pressure
The HFSP Journal, the interdisciplinary journal for scientists conducting high quality, innovative research at the interface between biology and the physical sciences is pleased to announce that the latest article modelling of tumor growth and metastasis. view more (2009-03-24)
Tumor mutations can predict chemo success
New work by MIT cancer biologists shows that the interplay between two key genes that are often defective in tumors determines how cancer cells respond to chemotherapy. view more (2009-08-07)
NSAIDs: Painkillers, inflammation inhibitors, anti-cancer drugs and new de-methylating agents
Researchers at the National Sun Yat-Sen University and Kaohsiung Medical University, Kaohsiung, Taiwan have revealed a new mechanism by which nonsteroidal anti-inflammatory drugs (NSAIDs) attenuate tumor invasion and metastasis. view more (2008-03-27)
First of its kind report on how children with brain tumors perform at school
While children who have had brain tumors perform worse in school than healthy kids, grades in foreign language are the most affected and girls have a harder time than boys in getting good grades. view more (2007-07-17)
Freezing kidney tumors is a safe alternative to surgery
Percutaneous cryoablation, a relatively non-invasive technique that destroys tumors by freezing them, is a safe method for treating kidney tumors in selected patients who are not considered candidates for surgery, according to a new study by researchers from the Mayo Clinic in Rochester, MN. view more (2006-05-01)
Prevent prostate cancer with antioxidants? Gene pathway may reveal more clues
Scientists from Maryland and New Jersey have identified a molecular pathway in mice that makes prostate cells vulnerable to cancer-causing oxygen damage. The pathway, which is also involved in human prostate cancer, may help determine how and whether antioxidants, such as certain vitamins or their products that reverse the damage, can prevent... view more... (2005-09-16)
October 15, 2009 Loss of Tumor-Suppressor and DNA-Maintenance Proteins Causes Tissue Demise, Penn Study Finds
A study published in the October issue of Nature Genetics demonstrates that loss of the tumor-suppressor protein p53, coupled with elimination of the DNA-maintenance protein ATR, severely disrupts tissue maintenance in mice. As a result, tissues deteriorate rapidly, which is generally fatal in these animals. In addition, the study provides... view more... (2009-10-16)
Flip of genetic switch causes cancers in mice to self-destruct, Stanford researchers find
Killing cancerous tumors isn't easy, as anyone who has suffered through chemotherapy can attest. But a new study in mice shows that switching off a single malfunctioning gene can halt the limitless division of tumor cells and turn them back to the path of their own planned obsolescence. view more (2007-07-31)
USC researchers discover breast cancer stem cells in bone marrow
Almost all tumor cells found in the bone marrow of early stage breast cancer patients appear to be breast cancer stem cells, suggesting the risk of disease spread for all breast cancer patients may be greater than previously thought. view more (2006-10-09)
Discovery in worms by Queen's researchers points to more targeted cancer treatment
Researchers at Queen's University have found a link between two genes involved in cancer formation in humans, by examining the genes in worms. The groundbreaking discovery provides a foundation for how tumor-forming genes interact, and may offer a drug target for cancer treatment. view more (2009-11-11)
Lowering your cholesterol may decrease your risk of cancer
Current research suggests that lowering cholesterol may block the growth of prostate tumors. The related report by Solomon et al, "Ezetimibe Is an Inhibitor of Tumor Angiogenesis," appears in the March 2009 issue of The American Journal of Pathology. view more (2009-02-24)
International Ludwig Institute for Cancer Research announces new branch director in London
The Ludwig Institute for Cancer Research (LICR) has appointed Professor Xin Lu as the new Director of the University College London (UCL) Branch of the LICR. The LICR has ten Branches around the world, each comprised of groups conducting cancer research as part of international thematic programs in the disciplines of genetics, biochemistry, cell... view more... (2004-10-18)
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