Tumor Suppressors Current Events | Tumor Suppressors News | 2
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New insights about what GIST tumors can be treated with medication
The fatal soft-part tumor GIST has only recently become treatable by medication. In further studies, a research team at The Sahlgrenska Academy at Göteborg University has now been able to determine what factors steer the prognosis and have therefore been able to show which patients should be considered for this new and effective, but also... view more... (2003-05-28)
NYU Langone Medical Center researchers find micro RNA plays a key role in melanoma metastasis
Scientists have long wondered how melanoma cells travel from primary tumors on the surface of the skin to the brain, liver and lungs, where they become more aggressive, resistant to therapy, and deadly. view more (2009-02-10)
WT1, male fertility and tumorigenesis
Detailed in an upcoming report in G&D, Dr. Miles Wilkinson and colleagues use a new tissue-specific RNAi approach they developed to identify a novel postnatal role for the Wilms' tumor 1 (WT1) tumor suppressor in spermatogenesis. view more (2006-01-16)
A genetic factor predicts prognosis in brain tumor patients
PLoS ONE has just published a study which defines a gene locus on chromosome 1 that predicts prognosis of brain tumor patients and may even set the basis for the development of more efficient drugs to combat brain cancer. view more (2007-06-28)
Protein marker associated with positive outcome in invasive breast cancer
Researchers at Sunnybrook and Women's College Health Sciences Centre have found a new protein marker linked to positive outcome in patients with breast cancer. view more (2005-11-16)
Role of autophagy in tumorigenesis
In the June 1 issue of G&D, Dr. Eileen White and colleagues at Rutgers University/University of Medicine and Dentistry of New Jersey/Cancer Institute of New Jersey, report, for the first time, that the cellular self-digesting process of autophagy can protect genome integrity - lending new insight into the seemingly contradictory roles of... view more... (2007-05-18)
Targeting the protein AEG1 impairs human liver cancer growth in mice
Hepatocellular carcinoma (HCC) is a highly aggressive form of liver cancer and one of the 5 most common cancers worldwide. Devanand Sarkar and colleagues, at Virginia Commonwealth University School of Medicine, Richmond, have now identified a gene that is expressed at high levels in human HCC tumor samples and generates a protein important for HCC... view more... (2009-02-17)
Therapeutic peptide frees the protein p73 to kill tumor cells
The protein p53 suppresses tumor development by potently inducing tumor cell death, making it an obvious target for anticancer therapeutics. view more (2007-03-09)
FDG-PET accurate for evaluating lung tumor destruction from radiofrequency ablation
FDG-PET can be used to assess the amount of tumor destruction after radiofrequency ablation (RFA)-the use of heat to destroy tumors-for the treatment of lung tumors and may provide more valuable information than CT alone, according to a new study. view more (2006-05-01)
UC Riverside Researchers Discover Model Organism For Studying Viruses that Affect Humans
Researchers at the University of California, Riverside have discovered that a simple worm, called C. elegans, makes an excellent experimental host for studying some of the most virulent viruses that infect humans. view more (2005-08-18)
Barrow study identifies new way to biopsy brain tumors in real time
A new miniature, hand-held microscope may allow more precise removal of brain tumors and an easier recognition of tumor locations during surgery. view more (2009-11-12)
SEK 20 million for brain tumor research
The M'Īrit and Hans Rausing Charitable Foundation in England has awarded SEK 20 million over five years to a research team at the Faculty of Medicine at Lund University in Sweden. The team is conducting the so-called BRIGTT Project (BRain Immuno Gene Tumor Therapy), which is pursuing laboratory work and clinical research to try to find new methods... view more... (2003-06-25)
Viral oncoprotein inactivation of p53
A group of scientists led by USC researcher Dr. Xiaojiang Chen lend structural insight into tumor suppressor inactivation by a viral oncoprotein. view more (2006-09-01)
An AIDS-related virus reveals more ways to cause cancer, Penn researchers find
Researchers at the University of Pennsylvania School of Medicine have shed new light on how Kaposi's Sarcoma-associated Herpes Virus (KSHV) subverts normal cell machinery to cause cancer. view more (2007-10-09)
Colorful spy tactics track live cells supporting cancerous tumors
A new advance in cellular imaging is allowing scientists to better understand the movement of cells in the area around tumors, also known as the tumor microenvironment. view more (2008-09-17)
Children's National researchers develop novel anti-tumor vaccine
A novel anti-tumor vaccine for neuroblastoma and melanoma developed by scientists and clinicians at Children's National Medical Center in collaboration with investigators from the University of Iowa is showing significant impact on tumor growth in mice. view more (2008-10-03)
Identifying the potential for tamoxifen resistance in patients
Tamoxifen is a widely used and highly successful drug in the treatment of breast cancer, though resistance to tamoxifen is still a concern in recurrent disease (affecting 25-35% of patients), since therapy resistant metastatic tumor cells are a major cause of death. view more (2009-06-11)
A new mathematical formula for cancer progression
Tumor progression can now be mapped less to mathematical standards and more to individual patients according to a new study by researchers at Harvard and Johns Hopkins Universities. view more (2007-11-09)
Dangerous skin cancer
The German Cancer Society has worked out new guidelines for the diagnosis and treatment of malignant melanoma-a disease with unfavorable prognosis. view more (2008-12-19)
Enhancement of pancreatic cancer on dynamic CT: Does it correlate with angiogenesis and fibrosis?
Prognosis of pancreatic cancer is poor. Recently, it has been clarified that the grade of tumor angiogenesis is a useful prognostic marker in human cancer, including pancreatic cancer. view more (2009-07-16)
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