Tumor Suppressors Current Events | Tumor Suppressors News | 8
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Novel 3-D cell culture model shows selective tumor uptake of nanoparticles
A nanoparticle drug delivery system designed for brain tumor therapy has shown promising tumor cell selectivity in a novel cell culture model devised by University of Nottingham scientists. view more (2007-08-23)
Homing nanoparticles pack multiple assault on tumors
A collaborative team led by Erkki Ruoslahti, M.D., Ph.D., of the Burnham Institute for Medical Research at UC Santa Barbara (Burnham) has developed nanoparticles that seek out tumors and bind to their blood vessels, and then attract more nanoparticles to the tumor target. view more (2007-01-09)
Ingredient Found In Green Tea Significantly Inhibits Breast Cancer Growth In Female Mice
Green tea is high in the antioxidant EGCG (epigallocatechin-3- gallate) which helps prevent the body's cells from becoming damaged and prematurely aged. view more (2008-04-08)
Curacyte scientists discover new anti-tumour agents
Curacyte AG, a Munich-based drug development company focused on novel treatments of inflammatory diseases, thrombotic disorders and cancer has announced today that its scientists have discovered a series of novel small molecule inhibitors of matriptase, a trypsin-like serine protease. Matriptase is an important mediator in the degradation of the... view more... (2003-06-17)
Researchers train the immune system to deliver virus that destroys cancer in lab models
An international team of researchers led by Mayo Clinic have designed a technique that uses the body's own cells and a virus to destroy cancer cells that spread from primary tumors to other parts of the body through the lymphatic system. view more (2007-12-19)
Why don't brain tumors respond to medication?
Malignant brain tumors often fail to respond to promising new medication. Researchers in Heidelberg have discovered a mechanism and a tumor marker for the development of this resistance. view more (2009-09-01)
A new chemotherapeutic target for hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a major health problem worldwide. Currently, the only chance for obtaining a cure in patients with HCC is by either a surgical resection or liver transplantation. view more (2007-10-25)
New method to inhibit growth of tumor cells
A new and promising way to inhibit the growth of tumor cells is the result of a collaborative effort between researchers Lars-Ã"¦ke Fransson and Mattias Belting at Lund University and a team in La Jolla, USA, led by cancer researcher Jeffrey Esko. Their work involves hampering the production of two substances that help tumor cells to grow... view more... (2001-12-21)
A potential route for human tumor gene therapy
The type 1 Na+/H+ exchanger (NHE1) is a transmembrane protein found in all eukaryotic cells. One of its functions is to evacuate excessive H+ in the cytoplasm by means of Na+-H+ exchange, resulting in stable intracellular pH value. view more (2008-05-21)
Waste disposal protein is mechanism behind cancer tumor suppression
"Taking out the trash" takes on a whole new meaning, as investigators at The Cancer Institute of New Jersey (CINJ) and Rutgers, The State University of New Jersey, have discovered that a waste disposal protein is the key to cancer tumor suppression in a process known as autophagy. view more (2009-06-12)
OHSU Cancer Institute researcher: radiation, immunotherapy gives greater effectiveness
Oregon Health & Science University Cancer Institute researchers have found the right formula of radiation and immunotherapy for fighting lung cancer tumors in mice, which they hope will translate to better treatment in human lung cancers. view more (2008-09-26)
A new significance of LVD and angiogenic MVD is identified in human primary SCRC
Lymphangiogenesis and angiogenesis are critical processes for tumor growth, invasion and metastasis. Angiogenesis has established its role in the development and progression of a variety of malignancies, playing a crucial role in the dissemination of the tumor cells. view more (2008-01-17)
Inhibitor of novel cancer target, LPAAT-beta, demonstrates selective anti-cancer effects in animal cancer models
Frankfurt, Germany: In a plenary session at the Symposium on Molecular Targets and Cancer Therapeutics, Dr Jack W. Singer, M.D. and Research Program Chairman of Cell Therapeutics, Inc. (CTI) today (Thursday 21 November) presented data from preclinical studies on a novel cancer target LPAAT-beta[1] in cultured cells and in preliminary animal... view more... (2002-11-17)
Treatment-induced growth factor causes cancer progression
In advanced cancer, anti-tumor therapies often work only partially or not at all, and tumors progress following treatment. view more (2007-04-06)
New biomarker predicts effectiveness of breast cancer drugs
University of Cincinnati (UC) researchers have identified a new way to predict when anti-estrogen drug therapies are inappropriate for patients with hormone-dependent breast cancer. view more (2006-12-08)
Does natural selection drive the evolution of cancer?
The dynamics of evolution are fully in play within the environment of a tumor, just as they are in forests and meadows, oceans and streams. This is the view of researchers in an emerging cross-disciplinary field that brings the thinking of ecologists and evolutionary biologists to bear on cancer biology. view more (2006-11-20)
Oncoproteins double-team and destroy vital tumor-suppressor
Two previously unconnected cancer-promoting proteins team up to ambush a critical tumor suppressor by evicting it from the cell's nucleus and then marking it for death by a protein-shredding mechanism, a team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in the Feb. 10 issue of Nature Cell Biology. view more (2008-02-15)
St. Jude study shows temporary improvement of tumor blood flow can improve chemotherapy
A treatment for neuroblastoma that lands a one-two punch works best when the second punch is timed to take maximum advantage of the first one, according to results of studies at St. Jude Children's Research Hospital. view more (2007-07-12)
Stopping the clock: Genetics of tumor latency in skin cancer
Dr. Anthony E. Oro and colleagues (Stanford University) have identified two key Gli protein degradation signals that directly affect tumor latency in a mouse model of human skin cancer. view more (2006-01-20)
Loss of caspase-8 makes neuroblastoma more aggressive
The caspase-8 gene plays a critical role in suppressing metastasis (spread) of neuroblastoma, and the expression of this gene is frequently absent in cancer cells that are aggressively metastasizing. view more (2006-01-06)
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