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Promising new methods of treatment for fatal abdominal tumor
GIST is a soft-parts tumor that occurs in the abdomen but is distinguishable from gastro-intestinal cancer. Previously, surgery has been the only treatment option since this type of tumor does not respond to either chemotherapy or radiation. Scientists at the Sahlgrenska Academy at Göteborg University have now shown that the prognosis for... view more... (2003-03-17)

Common molecule notifies immune system of prostate cancer
In experiments with mice, researchers have found that the body's immune system can use a surprisingly common molecule to recognize prostate tumors. The molecule comes from a protein found in all cells of the body; however, immune cells appear to respond to it only when it is present on the surface of cells within a tumor.   view more (2008-01-11)

'Destruct' triggers may be jammed in tumor cells, UF geneticists say
Tumor cells living in the cross hairs of radiation or chemotherapy may be able to escape death because their self-destruct mechanisms are jammed, say University of Florida scientists writing in a recent issue of Developmental Cell.   view more (2008-05-01)

Jefferson scientists find tumor suppressor gene protects against pre-cancerous development
Cell biologists at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia have provided further evidence that a gene thought to play a role in suppressing tumors actually can protect against the development of pre-cancerous cell growth as well.   view more (2006-11-02)

'1-hit' event provides new opportunity for colon cancer prevention, say Fox Chase researchers
More than 30 years ago, Alfred Knudson Jr., M.D., Ph.D., revolutionized the field of cancer genetics by showing that a person must lose both their paternal and maternal copies of a particular class of cancer-inhibiting genes, called tumor-suppressor genes, in order to develop cancer.   view more (2008-09-15)

New brain tumor model developed
A collaboration of researchers, led by Dr. Martine Roussel (St. Jude Children's Research Hospital), has developed a novel mouse model of medulloblastoma - the most prevalent malignant pediatric brain tumor.   view more (2005-10-31)

Enhanced DNA-repair mechanism can cause breast cancer
Although defects in the "breast cancer gene," BRCA1, have been known for years to increase the risk for breast cancer, exactly how it can lead to tumor growth has remained a mystery.   view more (2007-10-15)

Scripps research scientists show protein accelerates breast cancer progression in animal models
These new findings could lead to a better understanding of the molecular pathogenesis of breast cancer and focus attention on PTN and its signaling pathway as possible targets for new cancer therapies.   view more (2007-06-21)

7 years without a nose
Patients whose nose has been destroyed by a tumor or injury carry a severe psychological and social burden. Esthetic reconstruction ranges among the most challenging tasks in plastic surgery.   view more (2008-11-07)

Study details regulation of vital tumor suppressor gene p53
So vital is the p53 tumor suppressor gene in controlling cancer that its dysfunction is linked to more than half of human cancers.   view more (2007-09-06)

Scientists identify pancreatic cancer stem cells
Researchers at the University of Michigan Medical Center have, for the first time, identified human pancreatic cancer stem cells. Their work indicates that these cells are likely responsible for the aggressive tumor growth, progression, and metastasis that define this deadly cancer.   view more (2007-02-01)

Researchers Discover Method in Mice to Restore Tamoxifen Sensitivity in Resistant Breast Cancer
The widely used breast cancer drug tamoxifen (Nolvadex®), which can become less effective over time, might retain its full strength indefinitely if used along with a second drug, according to new research in mice conducted by investigators from the National Cancer Institute (NCI), part of the National Institutes of Health, and their partners.   view more (2006-12-21)

Researchers find way to make tumor cells easier to destroy
Tumors have a unique vulnerability that can be exploited to make them more sensitive to heat and radiation, researchers at Washington University School of Medicine in St. Louis report.   view more (2008-05-07)

Erectile dysfunction drugs allowed more chemotherapy to reach brain tumors in laboratory study
In a study using laboratory animals, researchers found that medications commonly prescribed for erectile dysfunction opened a mechanism called the blood-brain tumor barrier and increased delivery of cancer-fighting drugs to malignant brain tumors.   view more (2008-07-29)

New evidence supports century-old theory of cancer spread
A Yale School of Medicine study in the December issue of Lancet Oncology challenges mainstream oncology researchers to consider tumor cell hybridization with white blood cells as a major reason that cancer metastasizes or spreads to other parts of the body.   view more (2005-12-13)

New pathway could present an intervention point for cancer treatment
A new cellular pathway leads to destruction of a protein that promotes growth of breast, prostate and similar cancers and could provide a new avenue through which to pursue treatment of such diseases.   view more (2006-01-27)

Gold nanorods shed light on new approach to fighting cancer
Researchers have shown how tiny "nanorods" of gold can be triggered by a laser beam to blast holes in the membranes of tumor cells, setting in motion a complex biochemical mechanism that leads to a tumor cell's self-destruction.   view more (2007-10-17)

Breast Tumors in Mice Eradicated Using Cancer Vaccine
A team from the University of Pennsylvania School of Medicine has shown that by using a cancer vaccine based on the bacterium Listeria monocytogenes, they can cure mice with established breast tumors.   view more (2005-09-15)

Stopping the clock: Genetics of tumor latency in skin cancer
Dr. Anthony E. Oro and colleagues (Stanford University) have identified two key Gli protein degradation signals that directly affect tumor latency in a mouse model of human skin cancer.   view more (2006-01-20)

A new theoretical model of tumor growth and metastasis based on differences in tissue pressure
The HFSP Journal, the interdisciplinary journal for scientists conducting high quality, innovative research at the interface between biology and the physical sciences is pleased to announce that the latest article modelling of tumor growth and metastasis.   view more (2009-03-24)
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