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'Gateway' gene discovered for brain cancer
Researchers have discovered that the same genetic regulator that triggers growth of stem cells during brain development also plays a central role in the development of the lethal brain cancer malignant glioma. view more (2007-02-15)
Carbohydrate acts as tumor suppressor
Scientists at Burnham Institute for Medical Research (Burnham) have discovered that specialized complex sugar molecules (glycans) that anchor cells into place act as tumor suppressors in breast and prostate cancers. view more (2009-07-07)
Loss of caspase-8 makes neuroblastoma more aggressive
The caspase-8 gene plays a critical role in suppressing metastasis (spread) of neuroblastoma, and the expression of this gene is frequently absent in cancer cells that are aggressively metastasizing. view more (2006-01-06)
Tumor size related to lung cancer spread
Smaller tumors in the lungs appear to be less likely to have spread than larger tumors among patients with asymptomatic lung cancer, suggesting that early screening may be useful in detecting cancers that are still curable. view more (2006-02-14)
Cancer stem cells: know thine enemy
Stem cells -- popularly known as a source of biological rejuvenation -- may play harmful roles in the body, specifically in the growth and spread of cancer. view more (2007-12-26)
MIT sheds light on how tumor cells form
MIT cancer researchers have discovered a process that may explain how some tumor cells form, a discovery that could one day lead to new therapies that prevent defective cells from growing and spreading. view more (2006-06-22)
Cancer stem cells can go it alone
At the heart of most, if not all cancers, lie a handful of wayward stem cells that feed the ever growing tumor mass, but their scarcity make it difficult for scientists to study them. view more (2007-06-12)
Novel 'on-off switch' mechanism stops cancer in its tracks
A tiny bit of genetic material with no previously known function may hold the key to stopping the spread of cancer, researchers at Yale School of Medicine and Sichuan University in Chengdu, China report in two papers in the September 7-11 issue of Proceedings of the National Academy of Sciences. view more (2009-09-24)
Study links nicotine with breast cancer growth and spread
A study published in Cancer Research, a journal of the American Association for Cancer Research, suggests a possible role for nicotine in breast tumor development and metastases. view more (2008-10-15)
FOXO factor promotes survival of oxygen-deprived cancer cells
Scientists report that an evolutionarily conserved transcription factor may have both positive and negative effects on the growth of tumors, depending on whether or not the tumor cells have enough oxygen. view more (2007-12-28)
Waste disposal protein is mechanism behind cancer tumor suppression
"Taking out the trash" takes on a whole new meaning, as investigators at The Cancer Institute of New Jersey (CINJ) and Rutgers, The State University of New Jersey, have discovered that a waste disposal protein is the key to cancer tumor suppression in a process known as autophagy. view more (2009-06-12)
Promising advance in breast cancer research
Two new drugs, when combined, killed up to 75 percent of breast cancer tumor cells in mice and suppressed the regrowth of tumors, according to researchers at the Virginia Commonwealth University Massey Cancer Center. view more (2005-11-15)
New drug agent knocks out multiple enzymes in cancer pathway
A team of 24 researchers from the U.S., Europe, Taiwan and Japan and led by University of Illinois scientists has engineered a new anti-cancer agent that is about 200 times more active in killing tumor cells than similar drugs used in recent clinical trials. view more (2009-03-26)
Reversing cancer cells to normal cells
In earlier work, Northwestern University scientist Mary J.C. Hendrix and colleagues discovered that aggressive melanoma cells (but not normal skin cells nor less aggressive melanoma cells) contain specific proteins similar to those found in embryonic stem cells. view more (2007-04-30)
Mathematics reveals genetic pattern of tumor growth
Using mathematical theory, UC Irvine scientists have shed light on one of cancer's most troubling puzzles - how cancer cells can alter their own genetic makeup to accelerate tumor growth. view more (2007-06-25)
Blocking one protein helps cancer cells die of natural causes
Researchers have identified a protein fragment that keeps at least one major tumor suppressor gene from preventing cancer like it should. The fragment belongs to a class of proteins known as apoptotic enhancers (ASPP), named for their ability to stimulate programmed cell death, or apoptosis, by the p53 gene. But a study published in Nature... view more... (2003-01-08)
Researchers find how a common genetic mutation makes cancer radiation resistant
Many cancerous tumors possess a genetic mutation that disables a tumor suppressor called PTEN. Now researchers at Washington University School of Medicine in St. Louis have shown why inactivation of PTEN allows tumors to resist radiation therapy. view more (2009-06-10)
Stem cell protein offers a new cancer target
A protein abundant in embryonic stem cells is now shown to be important in cancer, and offers a possible new target for drug development, report researchers from the Stem Cell Program at Children's Hospital Boston. view more (2009-06-02)
FDG-PET accurate for evaluating lung tumor destruction from radiofrequency ablation
FDG-PET can be used to assess the amount of tumor destruction after radiofrequency ablation (RFA)-the use of heat to destroy tumors-for the treatment of lung tumors and may provide more valuable information than CT alone, according to a new study. view more (2006-05-01)
New method to inhibit growth of tumor cells
A new and promising way to inhibit the growth of tumor cells is the result of a collaborative effort between researchers Lars-Ã"¦ke Fransson and Mattias Belting at Lund University and a team in La Jolla, USA, led by cancer researcher Jeffrey Esko. Their work involves hampering the production of two substances that help tumor cells to grow... view more... (2001-12-21)
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