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New Cancer Gene Discovered
Researchers at the OU Cancer Institute have identified a new gene that causes cancer. The ground-breaking research appears Monday in Nature's cancer journal Oncogene. view more (2008-05-09)
Protein found to control tumor growth in certain breast cancers
This protein was previously thought to play a role solely in the innate immune system's response to bacterial infection. view more (2006-02-01)
Post-pregnancy events promote breast tumor metastasis
Changes in the tissue environment of the breast that occur after pregnancy promote the metastasis of breast tumor cells. view more (2006-02-03)
A potential route for human tumor gene therapy
The type 1 Na+/H+ exchanger (NHE1) is a transmembrane protein found in all eukaryotic cells. One of its functions is to evacuate excessive H+ in the cytoplasm by means of Na+-H+ exchange, resulting in stable intracellular pH value. view more (2008-05-21)
MicroRNAs as tumor suppressors
In the May 1st issue of G&D, Drs. Yong Sun Lee and Anindya Dutta (UVA) reveal that microRNAs can function as tumor suppressors in vitro. view more (2007-04-16)
MRI: A window to genetic properties of brain tumors
Doctors diagnose and prescribe treatment for brain tumors by studying, under a microscope, tumor tissue and cell samples obtained through invasive biopsy or surgery. view more (2008-03-25)
Multicenter study nets new lung tumor-suppressor gene
Collaborating scientists in Boston and North Carolina have found that a particular gene can block key steps of the lung cancer process in mice. view more (2007-08-06)
Agent orange chemical, dioxin, attacks the mitochondria to cause cancer, says Penn research team
Researchers with the University of Pennsylvania School of Veterinary Medicine have demonstrated the process by which the cancer-causing chemical dioxin attacks the cellular machinery, disrupts normal cellular function and ultimately promotes tumor progression. view more (2007-12-18)
New target for cancer therapy may improve treatment for solid tumors
Targeting and killing the non-malignant cells that surround and support a cancer can stop tumor growth in mice, reports a research team based at the University of Chicago Medical Center in the March 1, 2008, issue of the journal Cancer Research. The discovery offers a new approach to treating cancers that are resistant to standard therapy. view more (2008-03-04)
USC researchers develop new drug to target tumor cells and blood vessels
Researchers at the University of Southern California have identified a new drug compound that appears to target tumor cells and surrounding blood vessels without the negative side effects typically associated with Cox-2 inhibitors. view more (2009-04-20)
PET imaging response a prognostic factor after thoracic radiation therapy for lung cancer
A rapid decline in metabolic activity on a PET scan after radiation therapy for non-small cell lung cancer is correlated with good local tumor control, according to a study presented by researchers at Thomas Jefferson University Hospital at the 51st ASTRO Annual Meeting. view more (2009-11-09)
Metastatic movements in 3-D
Caswell et al.report in the Journal of Cell Biology how the altered behavior of integrins can prompt metastatic movement in tumor cells. view more (2008-10-06)
Antibody retards growth and induces death in liver cancer cells
Researchers from the University of Pittsburgh School of Medicine report a significant new advance in the search for an effective treatment for human liver cancer in the July issue of Molecular Cancer Therapeutics. view more (2007-07-12)
A fisheye view of the deadliest breast cancer
Inflammatory breast cancer (IBC) is the deadliest form of the disease, with fewer than half of those diagnosed today having a five-year prognosis for survival. view more (2006-12-13)
Interesting lead in the treatment of Ewing`s sarcoma
Research scientists at INSERM, CNRS and the Institut Curie, in collaboration with physicians, have used a mouse model to demonstrate the efficacy of an innovative therapeutic approach to Ewing`s sarcoma: the combination of human interferon (alpha or beta) and a common anti-tumor agent, ifosfamide. Their results were published in the November 2002... view more... (2002-10-31)
Researchers identify genes that allow brain cancer-causing stem cells to resist treatment
While great interest has followed the discovery of neural stem cells and their potential for someday treating diseases and injuries of the brain and spinal cord, recent research identified "cancer stem cells," a small population of cells that appear to be the source of cells comprising a malignant brain tumor. view more (2006-12-18)
Source of crucial immune cell in the skin discovered
Identification of precursor cell may lead to tumor immunotherapy as well as new treatment for rare disorder. view more (2006-01-30)
DKK-3 and WIF-1: Proteins related to liver cancer development?
Liver cancer is one of the most fatal human malignancies and the third most frequent cause of tumor-related death, about half a million people globally each year. view more (2009-06-15)
Does natural selection drive the evolution of cancer?
The dynamics of evolution are fully in play within the environment of a tumor, just as they are in forests and meadows, oceans and streams. This is the view of researchers in an emerging cross-disciplinary field that brings the thinking of ecologists and evolutionary biologists to bear on cancer biology. view more (2006-11-20)
Finding protection from tumor growth in unexpected places
Researchers have discovered that an enzyme commonly involved in regulating blood pressure also provides protection from tumor growth when strongly expressed in immune cells. view more (2007-06-06)
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