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Run amok enzyme causes same problems in both humans and fruit flies
An enzyme found at elevated levels in several human cancers has been linked to abnormal tumor growth in fruit flies, a discovery that provides a new model for understanding the link between stem cell biology and cancer, according to researchers at the University of Oregon. view more (2006-12-19)
MRI drug may improve cancer-killing ability of chemotherapy, study says
A contrast agent currently used in magnetic resonance imaging (MRI), called mangafodipir, may increase the cancer-killing ability of some chemotherapy drugs while protecting normal cells. view more (2006-02-15)
Children's National researchers develop novel anti-tumor vaccine
A novel anti-tumor vaccine for neuroblastoma and melanoma developed by scientists and clinicians at Children's National Medical Center in collaboration with investigators from the University of Iowa is showing significant impact on tumor growth in mice. view more (2008-10-03)
Signal protein shows promise for blocking tumor promoters in skin cells
A protein with the ironic name "Srcasm" can counteract the effects of tumor-promoting molecules in skin cells, according to new research by investigators at the University of Pennsylvania School of Medicine. view more (2006-11-06)
New therapeutic target for melanoma identified
A protein called Mcl-1 plays a critical role in melanoma cell resistance to a form of apoptosis called anoikis, according to research published this week in Molecular Cancer Research. view more (2009-04-16)
Research uncovers clues to virus-cancer link
In a series of recently-published articles, a research team from the University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center has uncovered clues to the development of cancers in AIDS patients. view more (2009-06-18)
New drug achieves pancreatic cancer tumor remission and prevents recurrence
Pancreatic cancer remains one of the deadliest cancers, but researchers may have found a combination therapy to reduce cancer stem cells and stop pancreatic cancer growth. Results will be presented at the American Association for Cancer Research 100th Annual Meeting 2009. view more (2009-04-20)
Identifying the potential for tamoxifen resistance in patients
Tamoxifen is a widely used and highly successful drug in the treatment of breast cancer, though resistance to tamoxifen is still a concern in recurrent disease (affecting 25-35% of patients), since therapy resistant metastatic tumor cells are a major cause of death. view more (2009-06-11)
Cellular molecule spurs growth of prostate cancer
University of North Carolina at Chapel Hill scientists have identified a molecule that stimulates the aggressive growth of prostate cancer. view more (2005-11-29)
Newly appreciated membrane estrogen receptor important therapeutic target for breast cancer
New research at Rhode Island Hospital has uncovered the biological effects of a novel membrane estrogen receptor, a finding that has potential implications for hormonal therapy for breast cancer. view more (2009-07-02)
New biomarker predicts effectiveness of breast cancer drugs
University of Cincinnati (UC) researchers have identified a new way to predict when anti-estrogen drug therapies are inappropriate for patients with hormone-dependent breast cancer. view more (2006-12-08)
Researchers pinpoint a new enemy for tumor-suppressor p53
Researchers at The University of Texas M. D. Anderson Cancer Center have identified a protein that marks the tumor suppressor p53 for destruction, providing a potential new avenue for restoring p53 in cancer cells. view more (2009-06-29)
Fly with brain tumor may shed light on cancer causing genes
A study showing how the expression of genes changes when the brain tissue of fruit flies becomes cancerous is published this week in BMC Genomics. As the function of many of these genes is conserved across evolution, the researchers expect their results will help us to understand why human brain tumors develop. The causes of brain tumor... view more... (2004-04-14)
Lung cancer: Molecular scissors determine therapy effectiveness
In the past few years, a number of anti-cancer drugs have been developed which are directed selectively against specific key molecules of tumor cells. view more (2009-03-17)
TGen researchers discover possible way to block the spread of deadly brain tumors
Researchers at the Translational Genomics Research Institute (TGen) may have found a way to stop the often-rapid spread of deadly brain tumors. view more (2009-04-20)
Strengthening the tumor-fighting ability of T cells
When faced with cancer, the immune system dispatches cells, called T cells, to kill the tumor. But these killer cells often fail to completely eliminate the tumor because they're deactivated by a distinct population of T cells known as regulatory T cells. view more (2008-03-25)
Tulane pioneers novel ovarian cancer treatment
The Tulane University Section of Hematology and Medical Oncology is investigating a novel treatment for ovarian cancer by using intravenous Ontak to deplete harmful cells that inhibit the body's natural immune response to fight cancer. Ovarian cancer is the fifth leading cancer killer of women in the United States. view more (2005-07-18)
New antibody profiling technique to test for lung cancer
Biomedical scientists have revealed a new and promising antibody profiling technique that provides a high degree of early diagnostic accuracy for non-small cell lung cancer cases. view more (2005-11-15)
Cancer-Causing Protein Can Also Help Fight the Tumors It Causes
Oncogenes are genes that when mutated or expressed in high concentrations can cause normal cells to become cancerous. view more (2009-06-19)
USC researchers discover novel way to develop tumor vaccines
Researchers at the University of Southern California (USC) have uncovered a new way to develop more effective tumor vaccines by turning off the suppression function of regulatory T cells. view more (2008-03-03)
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