Tumor cell Current Events | Tumor cell News | 8
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Tissue rigidity promotes tumor progression
Most investigations into cancer have focused on chemical signals, but a new research study provides rare insight into how mechanical force can regulate cellular behavior. view more (2005-09-20)
Mayo Clinic Researchers Find That Protein Believed to Protect Against Cancer Has a Mr. Hyde Side
In a biological rendition of fiction's Strange Case of Dr. Jekyll and Mr. Hyde, researchers from the Mayo Clinic campus in Florida and Harvard Medical School have found that a protein thought to protect against cancer development can actually spur the spread of tumors. view more (2009-09-04)
Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial
A molecular "off" switch packaged in a tiny sphere penetrates deeply into ovarian cancer tumor cells, stifling a troublesome protein and drastically reducing the size of tumors. view more (2006-08-15)
New, comprehensive tumor classification combines molecular biology and classic pathology
Information about the genetic make-up of tumors should, in the long term, help clinicians decide on the most effective course of treatment for patients with cancer. To be most helpful these molecular data must be incorporated into a tumor classification that includes morphological and clinical information. Jules Berman describes his ideas for a... view more... (2004-03-10)
Dangerous skin cancer
The German Cancer Society has worked out new guidelines for the diagnosis and treatment of malignant melanoma-a disease with unfavorable prognosis. view more (2008-12-19)
Science researchers genetically transform immune cells into tumor fighters
A team of researchers has genetically engineered normal immune cells to become specialized tumor fighters, demonstrating for the first time that these engineered cells can persist in the body and shrink large tumors in humans. view more (2006-09-01)
CSHL scientists identify and repress breast cancer stem cells in mouse tissue
By manipulating highly specific gene-regulating molecules called microRNAs, scientists at Cold Spring Harbor Laboratory (CSHL) report that they have succeeded in singling out and repressing stem-like cells in mouse breast tissue - cells that are widely thought to give rise to cancer. view more (2007-12-18)
Normalizing tumor vessels to improve cancer therapy
Chemotherapy drugs often never reach the tumors they're intended to treat, and radiation therapy is not always effective, because the blood vessels feeding the tumors are abnormal-"leaky and twisty" in the words of the late Judah Folkman, MD, founder of the Vascular Biology program at Children's Hospital Boston. view more (2008-08-26)
Researchers at Vanderbilt-Ingram Cancer Center uncover clue to explain invasive brain tumors
Researchers at the Vanderbilt-Ingram Cancer Center have uncovered a clue to explain the invasive nature of an aggressive kind of brain tumor called glioblastoma multiforme, or gliomas. view more (2006-01-12)
Researchers safely regenerate failing mouse hearts with programmed embryonic stem cells
Mayo Clinic researchers have safely transplanted cardiac preprogrammed embryonic stem cells into diseased hearts of mice successfully regenerating infarcted heart muscle without precipitating the growth of a cancerous tumor — which, so far, has impeded successful translation into practice of embryonic stem cell research. view more (2007-02-28)
Aminoguanidine: An attractive line as a multi-modal avenue to overcome tumor
Aminoguanidine is a compound that exerts multiple biological actions. Aminoguanidine has well described antioxidant properties and is also an inhibitor of nitric oxide synthases, the enzymes that produce nitric oxide. view more (2009-03-09)
Antibody Extends Life of Mice with Breast Cancer
A monoclonal antibody developed by researchers at the University at Buffalo has been shown to extend significantly the survival of mice with human breast-cancer tumors and to inhibit the cancer's spread to the lungs in the animals by more than 50 percent. view more (2006-12-12)
New model of p53 regulation proposed that suggests novel anticancer strategy
Genetically engineered mice convinced scientists at the Salk Institute for Biological Studies that it was time to overhaul widely held beliefs about how a powerful tumor suppressor called p53 is controlled in cells. view more (2006-04-12)
Enhancement of pancreatic cancer on dynamic CT: Does it correlate with angiogenesis and fibrosis?
Prognosis of pancreatic cancer is poor. Recently, it has been clarified that the grade of tumor angiogenesis is a useful prognostic marker in human cancer, including pancreatic cancer. view more (2009-07-16)
Testicular cancer gauge often not used
A standard part of testicular cancer care isn't used in more than half of all patients who have the condition, researchers at the University of Michigan Comprehensive Cancer Center have found. view more (2008-03-18)
Penn State College of Medicine research isolates liver cancer stem cells prior to tumor formation
Penn State College of Medicine researchers, in collaboration with colleagues at the University of Southern California, have taken an important step in understanding the role of stem cells in development of liver cancer. view more (2009-09-18)
A surprise 'spark' for pre-cancerous colon polyps
Researchers at Huntsman Cancer Institute (HCI) at the University of Utah studied the events leading to colon cancer and found that an unexpected protein serves as the "spark" that triggers formation of colon polyps, the precursors to cancerous tumors. view more (2009-05-15)
Tissue stiffness drives tumor formation
The relationship between tissue rigidity and tumor formation is fairly well established; however, what is not so well understood is what happens on a molecular level that contributes to such stiffness. view more (2005-09-23)
Researchers train the immune system to deliver virus that destroys cancer in lab models
An international team of researchers led by Mayo Clinic have designed a technique that uses the body's own cells and a virus to destroy cancer cells that spread from primary tumors to other parts of the body through the lymphatic system. view more (2007-12-19)
An effective target of biological therapy for hepatocellular carcinoma
It has been shown that constitutively activated STAT3 is detected in many HCC cell lines and tissues. This suggests that STAT3 is a promising molecular target for HCC gene therapy. view more (2009-06-15)
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