Ubiquitin Current Events | Ubiquitin News | 3
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Researchers pinpoint a new enemy for tumor-suppressor p53
Researchers at The University of Texas M. D. Anderson Cancer Center have identified a protein that marks the tumor suppressor p53 for destruction, providing a potential new avenue for restoring p53 in cancer cells. view more (2009-06-29)
Mechanism for Epstein-Barr virus protein's role in blood cancers discovered
Earlier this year, researchers at the University of Pennsylvania School of Medicine identified a link between a critical cancer pathway and an Epstein-Barr Virus (EBV) protein known to be expressed in a number of EBV-associated cancers. view more (2005-12-27)
Researchers identify new, cancer-causing role for protein
The mainstay immune system protein TRAF6 plays an unexpected, key role activating a cell signaling molecule that in mutant form is associated with cancer growth, researchers at The University of Texas M. D. Anderson Cancer Center report in the Aug. 28 edition of Science. view more (2009-08-28)
Water is 'designer fluid' that helps proteins change shape, scientists say
Ubiquitous on Earth, water also has been found in comets, on Mars and in molecular clouds in interstellar space. Now, scientists say this common fluid is not as well understood as we thought. view more (2008-08-07)
Cold Spring Harbor Scientists Reveal A Protein's Role in Enabling AIDS Virus to Reproduce
A team of scientists at Cold Spring Harbor Laboratory (CSHL) has discovered new details about how a simian strain of the AIDS virus replicates. view more (2008-05-27)
Oncoproteins double-team and destroy vital tumor-suppressor
Two previously unconnected cancer-promoting proteins team up to ambush a critical tumor suppressor by evicting it from the cell's nucleus and then marking it for death by a protein-shredding mechanism, a team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in the Feb. 10 issue of Nature Cell Biology. view more (2008-02-15)
Researchers find cause of frontotemporal dementia
Frontotemporal Dementia (FTD) is the second major form of dementia. view more (2006-07-17)
KEAP1 Keeps major cancer-promoting protein at bay
A tumor-suppressing protein snatches up an important cancer-promoting enzyme and tags it with molecules that condemn it to destruction, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports this week in the journal Molecular Cell. view more (2009-10-12)
Researchers find level of special protein is critical to proper formation of muscles
Proper formation of the proteins that power heart and skeletal muscle seems to rely on a precise concentration of a "chaperone" protein known as UNC-45, according to a new study. view more (2007-04-25)
Scripps scientists uncover mimicry at the molecular level that protects genome integrity
The new study, which was published on April 12, 2009, in an advanced online edition of the journal Nature Structural & Molecular Biology, draws new parallels between the Rad60 DNA repair factor and SUMO, a small ubiquitin-like modifier, which are both essential for maintaining genome stability during replication. view more (2009-04-14)
Researchers find two biomarkers with potential to predict breast cancer spread
Expression of two different proteins taken from primary tumor biopsies is highly associated with spread of breast cancer to nearby lymph nodes, according to researchers who say this protein profile could help identify at an early stage those patients whose disease is likely to metastasize. view more (2006-12-18)
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