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Electroacupuncture protects acetylsalicylic acid-induced acute gastritis in rats
Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used as anti-inflammatory and analgesic agents. However, they often cause gastrointestinal injury in gastric lesions by inhibiting COX (cyclooxygenase) and detailed mechanism remains unclear. Thus, effective strategies are required to protect the gastrointestinal mucosa.   view more (2009-03-03)

Surgery best option for preventing recurrence of venous leg ulcers (p 1854)
A UK study in this week's issue of THE LANCET highlights how surgery in addition to compression treatment could substantially reduce the risk of recurrent leg ulcers. Venous leg ulceration affects 1-2% of people and accounts for 1% of health costs in developed countries. Treatment includes compression, leg raising, and exercise; no randomised... view more... (2004-06-02)

Antioxidant herbal extract may help prevent and treat reflux oesophagitis
A herbal extract, which contains a powerful antioxidant, may help prevent and treat the extremely common and distressing condition reflux oesophagitis, shows research in Gut. Free radical damage to the lining of the oesophagus or gullet is probably more important than contact with stomach acid in the development of the condition, the study... view more... (2001-08-14)

A potential anti-ulcer herb medicine: Rocket 'Eruca sativa'
Gastric ulcer is an illness that affects a considerable number of people worldwide. Although the introduction of proton-pump inhibitors to the classic anti-ulcer therapy has revolutionized treatment of peptic ulcers and other gastrointestinal disorders, there is still no complete cure for this disease.   view more (2009-05-08)

Pneumatosis cystoids intestinalis after fluorouracil chemotherapy
The mechanism of pneumatosis cystoids intestinalis (PCI) is unclear. The mechanical and bacterial factors are most predominant causes of PCI.   view more (2008-09-18)

Diabetic Neurological Disease Could Affect Central Nervous System
Damage to the nervous system associated with diabetes could influence the central nervous system in addition to the peripheral nervous system, suggest authors of a pilot study published in this week's issue of THE LANCET. The origins of the neurological disorder diabetic neuropathy (distal symmetrical polyneuropathy), that affects a third of all... view more... (2001-07-05)

STDs disrupt genetic bottleneck that usually constrains HIV infection
Scientists have shown that HIV faces a genetic "bottleneck" when the virus is transmitted heterosexually from one person to another, by way of the genital mucosa.   view more (2009-01-23)

Infliximab may help prevent post-operative Crohn's disease recurrence
The administration of infliximab after intestinal resective surgery was found to be effective at preventing endoscopic and histological recurrence of Crohn's disease, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute.   view more (2009-02-02)

Gaps in intestinal barrier could cause Crohn's disease
Scientists at the University of Liverpool believe gaps in the intestinal barrier could be a cause of inflammatory diseases of the gut such as Crohn's Disease.   view more (2005-09-16)

AFRICAN HIV-1 EPIDEMIC NOT CAUSED BY MORE INFECTIOUS VIRAL SUBTYPE (p 1149)
The explosive HIV-1 epidemic in sub-Saharan Africa is unlikely to be the result of a viral subtype with increased infectivity, according to the results of a study published in this week’s issue of THE LANCET. The HIV-1 epidemic in eastern and southern sub-Saharan Africa is mainly caused by HIV-1 subtypes A, C, and D, whereas those in the USA... view more... (2001-04-11)

What effect does melatonin have in colitis?
In rats with experimental colitis, the marked increase in bacterial translocation in postcolitis rats has been reversed by melatonin administration. This is due to melatonin's anti-inflammatory and anti-apoptotic effects.   view more (2008-03-18)

New therapeutic targets in the treatment of ulcerative colitis
Social, environmental and dietary changes are associated with the changes of disease spectrum in a country. Ulcerative colitis has become a commonly seen disease in China, probably due to extensive consumption of Western foods in recent years.   view more (2007-11-14)

The largest colonic lipoma to date
Colonic lipomas have been found in related literature. One extremely rare case was recently reported in the November 14 issue of the World Journal of Gastroenterology because of its maximum diameter of 8.5 cm.   view more (2007-10-29)

'Mint' pain killer takes leaf out of ancient medical texts
A new synthetic treatment inspired by ancient Greek and Chinese remedies could offer pain relief to millions of patients with arthritis and nerve damage, a new University of Edinburgh study suggests.   view more (2006-08-22)

Immune signals of variations of a single gene linked to more severe Crohn's disease
Building on previous evidence supporting the theory that the pathophysiology of Crohn's Disease is altered by genetic variation, recent studies have found that the combination of immune signals given by three variants of a single candidate gene affects the severity of the disease, particularly among Ashkenazi Jews.   view more (2006-05-24)

CAPHOSOL relieves oral mucositis and improves quality-of-life in cancer patients
New data show that CAPHOSOL® (www.caphosol.com), an advanced electrolyte solution, relieves painful oral mucositis (OM) and improves quality of life for cancer patients undergoing chemotherapy and radiation therapy.   view more (2008-05-19)

Ulcerative colitis survey unmasks challenges for patients beyond devastating symptoms
Results released today from the Voices of UC survey of 1,000 ulcerative colitis (UC) patients underscore the extensive burden of the disease.   view more (2005-12-08)

No Justification For Early Laser Treatment Of Uncomplicated Childhood Haemangiomas (pp 502, 521)
Early laser treatment of uncomplicated childhood haemangiomas (strawberry birthmarks) is no more beneficial than no intervention, conclude authors of a UK study in this week's issue of THE LANCET. Childhood haemangiomas-the most common soft tissue tumours of infancy-occur in around 10% of children under one year of age. 90% of haemangiomas occur... view more... (2002-08-14)

Infliximab Could Prevent Sight Loss From Behcet's Disease (p 295)
A drug used to treat rheumatoid arthritis and Crohn's disease could play an important role in preventing sight loss associated with the inflammatory disorder Behcet's disease, suggest authors of a fast-track research letter published in this week's issue of THE LANCET. Beh'§et's disease is a rare condition (although with increased incidence in... view more... (2001-07-25)

New laboratory for research in gastroenterology
At 12.30 pm on Wednesday, 7 February, in the University of Liverpool, Nobel Laureate Professor Erwin Neher will open a £3 million laboratory for research into diseases of the gastrointestinal tract and the pancreas. The new laboratory will be used for research into pancreatitis, cancers of the colon, stomach and peptic ulceration. A... view more... (2001-02-07)
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