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Comparison of venlafaxine and SSRIs in the treatment of depression
There are numerous antidepressant medications currently on the market, but sadly, many patients still experience the debilitating symptoms of depression even with treatment.   view more (2008-02-22)

New evidence challenges recent changes in venlafaxine advice
In December 2004 the UK's Medicines and Healthcare products Regulatory Agency announced that, from that date, only specialists could prescribe venlafaxine. This change in advice followed three recently published observational studies, each of which concluded that patients prescribed antidepressants were more likely to take a fatal overdose if they... view more... (2005-05-05)

Study suggests MPA is effective treatment for hot flashes
Mayo Clinic researchers working with other North Central Cancer Treatment Group (NCCTG) investigators have found that a single dose of depomedroxyprogesterone acetate (MPA) more effectively reduces hot flashes than does the antidepressant venlafaxine (Effexor¬Æ)   view more (2006-03-01)

Some antidepressants associated with gastrointestinal bleeding
A class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs) appear to be associated with bleeding in the upper gastrointestinal tract.   view more (2008-07-08)

Switching medications, adding psychotherapy may help teens with ineffective depression medication
For adolescents with depression not responding to an initial treatment with a selective serotonin reuptake inhibitor (SSRI; a class of antidepressant drugs), switching medications and adding cognitive behavioral therapy resulted in an improvement in symptoms, compared to just changing medications.   view more (2008-02-27)

Antidepressants: benefit of SNRI is proven
The Institute for Quality and Efficiency in Health Care (IQWiG) was commissioned by the Federal Joint Committee (G-BA) to investigate whether patients with depression benefit from taking drugs belonging to the selective serotonin and norepinephrine reuptake inhibitor (SNRI) drug class.   view more (2009-08-26)

Venlafaxine extended-release effective for patients with major depression
Major depressive disorder (MDD) is the most common major mental illness, afflicting almost one in five individuals. More than 75% of people who recover from an episode of MDD will have at least one recurrence, with the majority having multiple recurrences.   view more (2007-12-13)

Researchers find depressed teens respond well to combination therapy
More than half of teenagers with the most debilitating forms of depression that do not respond to treatment with selective serotonin reuptake inhibitors (SSRIs) show improvement after switching to a different medication combined with cognitive behavioral therapy, researchers at UT Southwestern Medical Center and their colleagues in a multicenter... view more... (2008-02-27)

Genetic difference predicts antidepressant response
Researchers have identified subtle genetic variations that predict the efficacy of two widely used antidepressant drugs.   view more (2008-01-24)

Antidepressants aid electroconvulsive therapy in treating severe depression
Combining antidepressant drugs with electroconvulsive therapy (ECT) does a better job of reducing symptoms of severe depression and causes less memory loss than using ECT alone.   view more (2009-07-07)

Popularity Doesn't Necessarily Make Prozac Best Antidepressant Choice
Although Prozac has achieved phenomenal marketing success, it may not be as effective as certain other antidepressants, according to a recent systematic review.   view more (2005-12-07)

Practice parameters discuss treatment for narcolepsy, other hypersomnias of central origin
Practice parameters published in the December 1 issue of the journal SLEEP serve as both an update of previous practice parameters for the therapy of narcolepsy and as the first practice parameters to address treatment of other hypersomnias of central origin, including idiopathic hypersomnia, recurrent hypersomnia and hypersomnia due to medical... view more... (2007-12-03)

Treating SSRI-Resistant Depression
When your antidepressant medication does not work, should you switch to a different medication from the same class or should you try an antidepressant medication that has a different mechanism of action? This is the question asked by researchers in a new report scheduled for publication in Biological Psychiatry on April 1st.   view more (2008-03-26)

Some nonhormonal therapies may offer relief from hot flashes, but with possible adverse effects
A meta-analysis of previously published studies examining the use of nonhormonal therapies for treating menopausal hot flashes finds that some therapies are effective, but less so than estrogen, and have possible adverse effects that may restrict their use.   view more (2006-05-03)

Improving anxiety treatment through the help of brain imaging: A potential future treatment strategy
Wouldn't it be nice if our doctors could predict accurately whether we would respond to a particular medication" This question is important because research studies provide information about how groups of patients tend to respond to treatments, but inevitably, differences among groups of patients with the same diagnosis mean that findings... view more... (2008-05-09)

Efficacy and safety of Aripiprazole as adjunctive therapy in major depressive disorder
In adults with major depressive disorder, adding aripiprazole to antidepressant therapy (ADT) resulted in significant improvement in the primary endpoint, the Montgomery-Asberg Depression Rating Scale (MADRS) Total Score.   view more (2007-05-22)

Expectant brains help predict anxiety treatment success
A network of emotion-regulating brain regions implicated in the pathological worry that can grip patients with anxiety disorders may also be useful for predicting the benefits of treatment.   view more (2009-01-05)
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