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New study shows potential to treat or prevent viral cancers
A new study, presented at the SNM 55th Annual Meeting, shows that radioimmunotherapy (RIT) targeting viral antigens offers a novel option to treat-or even prevent-many viral cancers by targeting cancer cells expressing viral antigens or infected cells before they convert into malignancy.   view more (2008-06-17)

Cellular pathway yields potential new weapon in vaccine arsenal
When a cell has to destroy any of its organelles or protein aggregates, it envelopes them in a membrane, forming an autophagosome, and then moves them to another compartment, the lysosome, for digestion. Two years ago, Rockefeller University assistant professor Christian Münz showed that this process, called autophagy, sensitizes cells for... view more... (2006-12-27)

Einstein scientists treat cancer as an infectious disease -- with promising results
Researchers at the Albert Einstein College of Medicine of Yeshiva University have shown for the first time that cancers can be successfully treated by targeting the viruses that cause them.   view more (2007-10-31)

Immune exhaustion driven by antigen in chronic viral infection
A main reason why viruses such as HIV or hepatitis C persist despite a vigorous initial immune response is exhaustion. The T cells, or white blood cells, fighting a chronic infection eventually wear out.   view more (2009-05-14)

Vaccine to cope with viral diversity in HIV
The ability of HIV-1 to develop high levels of genetic diversity and acquire mutations to escape immune pressures contributes to our difficulties in producing a vaccine.   view more (2007-04-27)

Faithful mothers have healthier babies
Faculty of 1000 reviewers examine a study from New Zealand on whether prolonged exposure to the father's semen protects new mothers against pre-eclampsia and having an undersized baby   view more (2009-11-13)

Outfoxing pox: Developing a new class of vaccine candidates
In the annals of medicine, Edward Jenner's 1796 vaccination of a young boy against smallpox, using fluid from cowpox blisters, remains a landmark case. In a new study, Kathryn Sykes, a researcher at Arizona State University's Biodesign Institute and her colleagues have taken a fresh look at cowpox.   view more (2009-10-15)

LIAI Researchers Discover New Cellular Mechanism That Will Significantly Advance Vaccine Development
La Jolla Institute for Allergy & Immunology (LIAI) scientists have discovered one for the textbooks. Their finding, reported Friday in the scientific journal Immunity, illuminates a new, previously unknown mechanism in how the body fights a virus.   view more (2008-06-17)

Scientists identify new role for lung epithelial cells in sensing allergens in the air
Researchers at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and at Ghent University in Ghent, Belgium, have identified a new role for certain lung cells in the immune response to airborne allergens.   view more (2009-03-31)

Inducing Melanoma for Cancer Vaccine Development
Cancer vaccines are being investigated in early-phase clinical trials around the world, with many of those trials recruiting patients with melanoma.   view more (2006-03-28)

Malaria and Epstein-Barr virus linked to pediatric cancer in Africa
Endemic Burkitt lymphoma is a form of cancer that accounts for up to 74% of malignant disorders in children in equatorial Africa. Malaria and Epstein-Barr virus (EBV) are known cofactors in its development, but to date, their relative contribution has not been well understood.   view more (2007-06-08)

New approach to vaccine development provides potent, long-lasting immunity
The field of vaccine development is getting a boost from new research that has identified a promising vaccine delivery approach, which in animal studies produced long-term immune protection after just one immunization.   view more (2006-05-24)

The right messenger for a healthy immune response
Researchers from the Molecular Immunology group at the Helmholtz Centre for Infection Research (HZI) in Braunschweig, Germany have now shown that Beta-Interferon also plays a crucial role during an immune response: without Beta-Interferon immune cells are unable to show "wanted posters" of pathogens to other cells.   view more (2009-07-20)

Genome circularization and RNA virus replication
As featured on the cover of the August 15th issue of G&D, an Argentinian research team, led by Dr. Andrea Gamarnik, report on their recent discovery of a novel mechanism of dengue virus replication.   view more (2006-08-01)

Van Andel Institute Study Rules Out Transcriptional Coactivators as Useful Herpes Antiviral Drug Targets
Researchers at Van Andel Research Institute (VARI) have determined that the herpes simplex virus type 1 (HSV-1) does not require transcriptional coactivators for viral gene expression early in the infection process. The finding is significant in determining that, in contradiction to earlier models, chemical inhibitors of these cellular proteins... view more... (2009-03-26)

Scientists develop mathematical model to predict the immune response to influenza
Researchers at the University of Rochester have developed a mathematical model to predict immune responses to infection with influenza A viruses, including novel viruses such as the emergent 2009 influenza A (H1N1).   view more (2009-05-14)

Immunologists find better way to boost the immune system
Immunologists have discovered how to manipulate the immune system to increase its power and protect the body from successive viral infections.   view more (2008-01-23)

New technique points to safer, more efficient vaccination
Researchers have demonstrated a technique that has the potential to reduce the toxicity of vaccines and to make smaller doses more effective, according to a study published in PLoS Pathogens.   view more (2005-12-30)

Implants mimic infection to rally immune system against tumors
Bioengineers at Harvard University have shown that small plastic disks impregnated with tumor-specific antigens and implanted under the skin can reprogram the mammalian immune system to attack tumors.   view more (2009-01-23)

First results of the Narval trial (ANRS 088)
Patients with HIV infection may develop resistance to one or more of antiretroviral drugs to which they are exposed during treatment. The selection of the most appropriate drugs for switching therapy in patients who have developed resistance, is a difficult challenge. Both, genetic tests that identify mutations in viral genes associated with... view more... (2000-04-21)
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