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Viral Antigens Current Events | Viral Antigens News | 5

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Study to test drug's potential to preserve insulin production in newly diagnosed Type 1 diabetics
A drug used to treat lymphoma, rheumatoid arthritis and other immune disorders may enable newly-diagnosed type 1 diabetics to save some of their pancreas function and thereby reduce their susceptibility to long-term complications.   view more (2006-03-16)

Yale scientists create artificial 'cells' that boost the immune response to cancer
Using artificial cell-like particles, Yale biomedical engineers have devised a rapid and efficient way to produce a 45-fold enhancement of T cell activation and expansion, an immune response important for a patient's ability to fight cancer and infectious diseases, according to an advance on line report in Molecular Therapy.   view more (2008-02-27)

'Resonance' may explain virologic failure in STI drug therapy
Researchers have been puzzled over why HIV-positive patients who have periodic, built in interruptions in their drug therapy reach a point where the therapy no longer reduces their viral loads, even in the absence of any evidence of acquired drug resistance.   view more (2006-04-14)

Penn scientists find a protein that inhibits Ebola from reaching out to infect neighboring cells
Scientists at the University of Pennsylvania School of Veterinary Medicine have identified a protein, ISG15, that inhibits the Ebola virus from budding, the process by which viruses escape from cells and spread to infect neighboring cells.   view more (2008-03-04)

Viral recombination another way HIV fools the immune system
When individuals infected with HIV become infected with a second strain of the virus, the two viral strains can exchange genetic information, creating a third, recombinant strain of the virus. It is known that the presence of multiple viral strains, called superinfection, frequently leads to a loss of immune control of viral levels.   view more (2008-07-22)

Viral infection at birth linked to cerebral palsy
Exposure to certain viral infections shortly before and after birth (the perinatal period) is associated with cerebral palsy, finds a study published online by the BMJ today.   view more (2006-01-06)

Penn researchers determine structure of smallpox virus protein bound to DNA
Researchers at the University of Pennsylvania School of Medicine have determined the structure of an important smallpox virus enzyme and how it binds to DNA.   view more (2006-08-07)

Researchers discover how compounds prevent viruses from entering cells
Compounds called defensins-known to prevent viruses from entering cells-appear to do so by preventing the virus from merging to cells' outer membrane.   view more (2005-09-16)

HIV handicaps itself to escape immune system pressure
People with the ability to stave off AIDS for years after initial infection by HIV have been called "long-term non-progressors" or "elite controllers."   view more (2009-04-16)

Exhaustion of HIV-specific T cells may be caused by chronic exposure to virus
The "exhaustion" of immune cells that target HIV appears to result from chronic exposure to the virus, specifically exposure to the particular protein segments targeted by the pathogen-killing HIV-specific CD8 T cells.   view more (2008-05-06)

Effective HIV control may depend on viral protein targeted by immune cells
An effective response of the immune system's 'killer' T cells against infection with HIV may depend on exactly which viral protein is targeted, according to an international group of researchers.   view more (2006-12-18)

Scripps research scientists reveal key structure from ebola virus
Described in the July 10, 2008 issue of the journal Nature, the research reveals the shape of the Ebola virus spike protein, which is necessary for viral entry into human cells, bound to an immune system antibody acting to neutralize the virus.   view more (2008-07-10)

UVA studies potential target for skin cancer treatment
When normal skin cells become a melanoma tumor, they sometimes turn on genes not usually found in the skin.   view more (2006-10-04)

Animal studies show promise for development of human SARS immunisation (pp 2102, 2122, 2139)
An article and research letter in this week's issue of THE LANCET provide evidence for the effectiveness of experimental SARS immunisation in animal studies. Although further research is required, these preliminary results show the potential for the development of human SARS immunisation. Alexander Bukreyev from the US National Institutes of... view more... (2004-06-23)

Web model of influenza-host lifecycles will aid scientists in creating anti-viral drugs
A "starry sky" map linking the myriad interactions between the influenza virus and its human host will help guide researchers in creating new anti-viral drugs, say researchers at UT Southwestern Medical Center.   view more (2006-01-31)

New cost-effective means to reconstruct virus populations
Researchers from the United States and Switzerland have developed mathematical and statistical tools for reconstructing viral populations using pyrosequencing, a novel and effective technique for sequencing DNA. They describe their findings in an article published May 9th in the open-access journal PLoS Computational Biology.   view more (2008-05-09)

oes peripheral T-lymphocyte subpopulations correlate with hepatitis B virus load?
Hepatitis B virus (HBV) infection is a dynamic process with variable biochemical, virological and histological profiles at different stages of the infection, depending on host and viral factors. Furthermore, this profile may change at a variable pace over time.   view more (2009-07-29)

Asthma risk increases in children treated for HIV
Children whose immune systems rebound after treatment with potent anti-viral drugs for HIV infection face an increased risk of developing asthma, said a federally funded consortium of researchers led by those from Baylor College of Medicine in a report that appears online in the Journal of Allergy and Clinical Immunology.    view more (2008-07-02)

New technology for boosting vaccine efficiency
One of the most pressing biomedical issues is the development of techniques that increase the efficiency of vaccines. In a paper published on April 24, 2008 in the journal Vaccine, a Massachusetts's biotechnology company, Cure Lab, Inc. has proposed a new technology for anti-viral vaccination.   view more (2008-04-25)

Link uncovered between viral RNA and human immune response
In its fight against an intruding virus, an enzyme in our immune system may sense certain types of viral RNA pairs, according to scientists.   view more (2009-08-05)
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