Viral Antigens Current Events | Viral Antigens News | 7
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Early-stage immune system control of HIV may depend on inherited factors
How well an individual's immune system controls HIV during the earliest phases of infection appears to depend on both the specific versions of key immune-system molecules called HLA Class I that have been inherited, as well as on the fragments of viral protein those molecules display to the T lymphocytes that usually destroy infected cells. view more (2006-11-06)
New study pinpoints unique genetic susceptibility for viral encephalitis
In the study, the researchers suggest that herpes simplex encephalitis may reflect a single gene immunodeficiency that confers susceptibility to herpes simplex virus, an idea that contrasts with the prevailing scientific theory of how genes work to make people vulnerable to infections. view more (2006-09-18)
T cell-based HIV vaccine candidate demonstrates positive results
The question of whether or not to continue to pursue the development of T-cell-based HIV-1 vaccines has been a source of controversy following last year's widely publicized failure of the field's most promising candidate, a vaccine developed by Merck known as V520. view more (2008-11-10)
New target for cancer therapy may improve treatment for solid tumors
Targeting and killing the non-malignant cells that surround and support a cancer can stop tumor growth in mice, reports a research team based at the University of Chicago Medical Center in the March 1, 2008, issue of the journal Cancer Research. The discovery offers a new approach to treating cancers that are resistant to standard therapy. view more (2008-03-04)
Chronic infection persists by targeting stromal cell network in lymphoid organs
One of the biggest challenges to treating infectious diseases and developing preventive vaccines is the ability of many chronic infections to suppress the immune T-cell response over time. view more (2007-09-19)
Clue found to Epstein-Barr virus' ability to form and sustain tumors
Researchers at the University of Wisconsin School of Medicine and Public Health (SMPH) have found a viral target that opens the door for the development of drugs to destroy tumors caused by Epstein-Barr virus (EBV). view more (2006-09-06)
AIDS research agenda proposed
In an Editorial Review published in the current issue of AIDS (2006,20,7, 1-5), HIV researchers from Argentina, Australia, South Africa, and the United States address the challenging question of the impact of major social, ecological, political, economic, biomedical, viral, and other changes on the HIV epidemic and the world's ability to respond. view more (2006-04-12)
Immune mechanism could help explain transient immune suppression often seen in acute infections
Scientists have discovered that at the same time the immune system is vigorously attacking invading viruses or bacteria, it is unexpectedly reducing its production of a particular type of factor that directs the movement of immune cells. view more (2007-08-03)
Molecular 'on/off switch' controls immune defenses against viruses
Much like flipping a light switch, the hepatitis C virus turns on human immune defenses upon entering the body but also turns off those defenses by manipulating interaction of key cellular proteins, UT Southwestern Medical Center researchers have found. view more (2006-12-26)
Methods for gene transfer in stem cells featured in Cold Spring Harbor Protocols
Vectors derived from retroviruses are useful tools for long-term gene transfer because they allow stable integration of transgenes and propagation into daughter cells. view more (2009-08-06)
A protein sequence associated with Huntington's disease may become life-saving vaccine component
On June 10, 2008 the scientific journal "Vaccine" published a paper by the Massachusetts based biotech company Cure Lab, Inc., demonstrating that a protein sequence important in neurodegenerative Huntington's disease can be safely used as a new generation of vaccine adjuvants. view more (2008-06-11)
Revolution in the fight against cancer & viruses
A recent scientific discovery could herald the introduction of fast, effective treatments for cancer and viruses. view more (2006-05-26)
Hoping for a fluorescent basket case
Although recent advances have raised hopes that a protective vaccine can be developed, acquired immunodeficiency syndrome (AIDS) remains a major public health problem. view more (2009-11-13)
Novel antigen-cloning technique may boost efforts to develop a melanoma vaccine
In recent years, researchers have worked to develop a number of vaccines to help the immune system fight tumors. Cancer vaccines are not intended to prevent cancer; rather, they are used to boost immune responses to preexisting tumors. view more (2007-04-16)
Ultra deep sequencing identifies HIV drug resistance at early stage
Rare, previously undetectable drug-resistant forms of HIV have been identified by Yale School of Medicine researcher Michael Kozal, M.D., using an innovative genome sequencing technology that quickly detects rare viral mutations. view more (2007-06-18)
A potential approach to treatment of hepatitis B virus infection
Eukaryotic cells employ multiple strategies of checkpoint signaling and DNA repair mechanisms to monitor and repair damaged DNA. view more (2008-09-10)
New Strategy for Inhibiting Virus Replication
Viruses need living cells for replication and production of virus progeny. Thus far, antiviral therapy primarily targets viral factors but often induces therapy resistance. New improved therapies attempt to targets cellular factors that are essential for viral replication. view more (2009-08-17)
Harmless virus may hold key to more effective HIV drug discovery
A simple, harmless virus might hold the key to the more effective and efficient development of HIV and anti-viral drugs, UCI chemical biologists have found. view more (2005-08-29)
High HPV concentrations combined with smoking significantly raise risks of cervical cancer
Cigarette smoking and concurrent infection with high levels of the virus associated with cervical cancer can increase cancer risk by as much as 27 times, according to a study published in the November 2006 issue of Cancer Epidemiology, Biomarkers & Prevention. view more (2006-11-17)
Features of replication suggest viruses have common themes, vulnerabilities
A study of the reproductive apparatus of a model virus is bolstering the idea that broad classes of viruses - including those that cause important human diseases such as AIDS, SARS and hepatitis C - have features in common that could eventually make them vulnerable to broad-spectrum antiviral agents. view more (2007-08-14)
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