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HIV inserts into human genome using a DNA-associated protein
A human DNA-associated protein called LEDGF is the first such molecule found to control the location of HIV integration in human cells. view more (2005-11-28)
Not just a long distance relationship: immune cells in skin fight off infection better than the rest
Scientists at the University of Melbourne have discovered the local action of immune cells in the skin, which could improve treatment of viral skin infections. view more (2009-04-08)
Dengue Virus Reveals Its Circular Secret
The first step in the transmission of mosquito-borne viruses is no mystery: it's the pesky insect's bite that allows the virus to enter its victim's bloodstream. But for some of the most dangerous insect-borne viruses, details of what happens next have been unclear. view more (2006-08-02)
New insights into how brain responds to viral infection
Scientists at Columbia University Mailman School of Public Health have discovered that astrocytes, supportive cells in the brain that are not derived from an immune cell lineage, respond to a molecule that mimics a viral infection using cellular machinery similar to that used by classical immune cells in the blood. view more (2009-04-01)
Evolutionary 'battle scars' identify enhanced anti-viral activity
Rapid evolution of a protein produced by an immunity gene is associated with increased antiviral activity in humans, a finding that suggests evolutionary biology and virology together can accelerate the discovery of viral-defense mechanisms, according to researchers at Fred Hutchinson Cancer Research Center. view more (2008-01-25)
Getting wise to the influenza virus' tricks
Influenza is currently a grave concern for governments and health organisations around the world. The worry is the potential for highly virulent bird flu strains, such as H5N1, to develop the ability to infect humans easily. New drugs and vaccines to halt the spread of the virus are badly needed. view more (2008-05-05)
What is the influence of tumor removal on the serum level of carbohydrate's antibody?
Cancer immune surveillance is considered to be important in the anti-tumor protection of the host. The growing tumor escapes the immune control under the immunosuppressive conditions. view more (2008-10-08)
Mars and Venus: Short- and long-term success of male to female kidney transplants
Female recipients of kidneys from deceased male donors demonstrate an increased risk of allograft failure in the first year after transplant, but show no increased risk after ten years. view more (2009-07-30)
New study shows that therapeutic gene expression can be sustainable for 1 year
Researchers at the Board of Governors Gene Therapeutics Research Institute at Cedars-Sinai Medical Center have shown for the first time that it is possible to sustain therapeutic gene expression in the central nervous system for up to a year, even in the presence of an anti-viral immune response mechanism that is normally present in humans. view more (2007-10-26)
Are you one of the few that respond to treatment for hepatitis C?
In some patients resistance to treatment for hepatitis C can be detected as early as the first three days of treatment, according to a team of scientists in a recent article published in Hepatology. This knowledge should help clinicians predict the effectiveness of individual treatments and consequently decide who should go through such a regimen.... view more... (2003-06-24)
Using Nanoparticles, In Vivo Gene Therapy Activates Brain Stem Cells
Using customized nanoparticles that they developed, University at Buffalo scientists have for the first time delivered genes into the brains of living mice with an efficiency that is similar to, or better than, viral vectors and with no observable toxic effect, according to a paper published this week in Proceedings of the National Academy of... view more... (2005-07-26)
Study Characterizes Eczema Patients Most at Risk for Dangerous Viral Infections
Eczema patients at risk for serious viral infections have more severe disease, are more likely to be allergic to food and other allergens, and have a frequent history of staph infections. view more (2009-06-25)
Gene-specific Ebola therapies protect non-human primates from lethal disease
Scientists have developed a successful strategy for interfering with Ebola virus infection that protected 75 percent of nonhuman primates exposed to the lethal disease. view more (2006-01-13)
Immune system response to viral DNA is unique
The human body has a unique immune system response to foreign DNA, suggesting that DNA viruses and RNA viruses are detected by different mechanisms. view more (2006-01-25)
Children's National researchers develop novel anti-tumor vaccine
A novel anti-tumor vaccine for neuroblastoma and melanoma developed by scientists and clinicians at Children's National Medical Center in collaboration with investigators from the University of Iowa is showing significant impact on tumor growth in mice. view more (2008-10-03)
UT Southwestern researchers develop new strategy for broad spectrum anti-viral drugs
Bavituximab, an anti-viral drug developed by UT Southwestern Medical Center researchers, shows promise as a new strategy to fight viral diseases, including potential bioterrorism agents. view more (2008-11-24)
Researchers Examine Evolution of Genes that Trigger the Body's Immune Response to Viral Infection
Virginia Commonwealth University Institute of Molecular Medicine researchers have traced the evolutionary origin of two genes that serve as primary cellular sensors of infection with RNA viruses, such as influenza, poliovirus, West Nile virus, and HIV, which may ultimately provide researchers with insight into a possible new pathway for the... view more... (2008-10-22)
Aids : Effectiveness of antiretroviral therapy demonstrated in Africa
Tritherapies using antiretroviral drugs have proved their worth in industrialized countries in the fight against Aids. However, in Sub-Saharan Africa, where 70 % of people infected with HIV live, access to such treatments is extremely limited. High cost, complicated procedures, combined with inadequate infrastructures for following up patients or... view more... (2002-06-27)
New gene regulation mechanism discovered
Researchers at Cold Spring Harbor Laboratory have discovered a new kind of messenger RNA molecule that is converted from non-protein coding status to protein coding status in response to cellular stress such as viral infection. view more (2005-10-21)
Research into viral infections: Cardiff University enters agreement with Glaxo Wellcome Inc.
The collaboration is based on the work of the research group of Professor Chris McGuigan at Cardiff University's Welsh School of Pharmacy, which has discovered a new method for inserting charged molecules into living cells. The Cardiff team is collaborating with virologists at the Rega Institute1 in Belgium on this invention, which may have major... view more... (1999-07-20)
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