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Gene expression profiling of dengue virus infection in cell lines and patients
Researchers at the Novartis Institute for Tropical Diseases and the Genome Institute of Singapore have identified new host genes associated with dengue virus infection, which may open new avenues to developing a drug to treat the disease.   view more (2007-11-07)

Cranberries can treat herpes
Alpine cranberries have significant biological activity that can help to combat herpes virus type II (HSV-2) infection, one of the most common viral infections in humans, writes Emma Dorey in Chemistry & Industry.   view more (2004-10-15)

Van Andel Institute Study Rules Out Transcriptional Coactivators as Useful Herpes Antiviral Drug Targets
Researchers at Van Andel Research Institute (VARI) have determined that the herpes simplex virus type 1 (HSV-1) does not require transcriptional coactivators for viral gene expression early in the infection process. The finding is significant in determining that, in contradiction to earlier models, chemical inhibitors of these cellular proteins... view more... (2009-03-26)

UCR-led study identifies crucial mechanism involved in immune response against viruses
A research team led by UC Riverside scientists has shown that the common fruit fly can serve as an excellent model for studying the immunity animals are born with for fighting viral infections.   view more (2006-03-24)

Immune exhaustion driven by antigen in chronic viral infection
A main reason why viruses such as HIV or hepatitis C persist despite a vigorous initial immune response is exhaustion. The T cells, or white blood cells, fighting a chronic infection eventually wear out.   view more (2009-05-14)

Bird flu leaves the nest -- adapting to a new host
Current research suggests that viral polymerase may provide a new therapeutic target for host-adapted avian influenza.   view more (2009-08-27)

STDs disrupt genetic bottleneck that usually constrains HIV infection
Scientists have shown that HIV faces a genetic "bottleneck" when the virus is transmitted heterosexually from one person to another, by way of the genital mucosa.   view more (2009-01-23)

oes peripheral T-lymphocyte subpopulations correlate with hepatitis B virus load?
Hepatitis B virus (HBV) infection is a dynamic process with variable biochemical, virological and histological profiles at different stages of the infection, depending on host and viral factors. Furthermore, this profile may change at a variable pace over time.   view more (2009-07-29)

Study finds genetic influence on pace of HIV/AIDS progression
Viral load-the amount of virus in the blood of an HIV-infected person-has long been viewed as the chief indicator of how quickly someone infected with HIV infection progresses to AIDS.   view more (2007-10-23)

Immune exhaustion in HIV infection
As HIV disease progresses in a person infected with the HIV virus, a group of cells in the immune system, the CD8+ T lymphocytes, become "exhausted," losing many of their abilities to kill other cells infected by the virus.   view more (2008-05-06)

Bioportfolio: Life-long persistence of erythrovirus DNA genomes in human tissue
The researchers at the University of Helsinki, Finland, and University Hospital of Bonn, Germany, have coined the novel term "Bioportfolio" to describe viral genomic material remaining in the human body after infection.   view more (2006-04-26)

Herpes virus link to complications in pregnancy
Researchers at Adelaide's Women's & Children's Hospital and the University of Adelaide, Australia, have made a world-first discovery that links viral infection with high blood pressure during pregnancy and pre-term birth.   view more (2008-02-19)

New method for HIV testing holds promise for developing world
A new technique that detects the HIV virus early and monitors its development without requiring refrigeration may make AIDS testing more accessible in sub-Saharan Africa.   view more (2009-07-22)

Blocking effects of viral infections may prevent asthma in young children
Babies who get severe respiratory viral infections are much more likely to suffer from asthma as they get older.   view more (2007-11-08)

Viral infection at birth linked to cerebral palsy
Exposure to certain viral infections shortly before and after birth (the perinatal period) is associated with cerebral palsy, finds a study published online by the BMJ today.   view more (2006-01-06)

Yale study explains complex infection fighting mechanism
Yale School of Medicine researchers report in Nature Immunology how infection fighting mechanisms in the body can distinguish between a virus and the healthy body, shedding new light on auto immune disorders.   view more (2006-01-11)

New technique kills cancer virus without harming healthy cells
Major breakthrough could lead to successful treatment of viral cancers, without side-effects. Yorkshire Cancer Research funded researchers at the University of York have made a major cancer breakthrough. Using a new technique called RNA interference, they have successfully killed human cervical cancer cells grown in culture without causing damage... view more... (2002-09-03)

Viral oncoprotein inactivation of p53
A group of scientists led by USC researcher Dr. Xiaojiang Chen lend structural insight into tumor suppressor inactivation by a viral oncoprotein.   view more (2006-09-01)

A potential approach to treatment of hepatitis B virus infection
Eukaryotic cells employ multiple strategies of checkpoint signaling and DNA repair mechanisms to monitor and repair damaged DNA.   view more (2008-09-10)

Early treatment is key to combating hepatitis C virus
Canadian researchers have shown that patients who receive early treatment for Hepatitis C virus (HCV) within the first months following an infection, develop a rapid poly-functional immune response against HCV similar to when infection is erradicted spontaneously, according to a new study published in the Journal of Virology.   view more (2008-08-11)
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