Warfarin Current Events | Warfarin News
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Right warfarin dose determined by 3 genes
Researchers at Uppsala University, together with colleagues at the Karolinska Institute and the Sanger Institute, have now found all the genes the determine the dosage of the blood-thinning drug warfarin. The findings are published in the scientific journal PLoS Genetics. view more (2009-03-20)
New blood-thinning drug safer than rat poison
In an article reviewed by F1000 Medicine Faculty Members Robert Ruff, Brian Olshansky and Luis Ruilope, the blood-thinner dabigatran is shown to protect against stroke, blood clotting and major bleeding as effectively as warfarin, but with fewer side effects. view more (2009-09-30)
Drug linked to increase in brain hemorrhage cases
The rate of brain hemorrhages associated with blood thinning drugs quintupled during the 1990s, according to a study published in the January 9, 2007, issue of Neurology, the scientific journal of the American Academy of Neurology. In people over age 80, the rate increased more than tenfold. view more (2007-01-09)
New discovery sparks hope of safer dosage of Warfarin
The blood-thinning drug Warfarin tops the list of drug side-effects in Sweden. Patient sensitivity to Warfarin varies, which can lead to over-dosage and in certain cases to death. A study led by Mia Wadelius at Uppsala University in Sweden, together with researchers in Cambridge, indicates that two genes may be the explanation. The findings are... view more... (2005-05-13)
Dabigatran vs. warfarin as long-term anticoagulant therapy in atrial fibrillation
The anticoagulant dabigatran is more effective than warfarin in the prevention of stroke in patients with atrial fibrillation, according to results from the RE-LY study (Randomized Evaluation of Long-term anticoagulant therapY). view more (2009-08-31)
Blood thinning drug linked to increased bleeding in brain
A new study shows that people who take the commonly used blood thinning drug warfarin may have larger amounts of bleeding in the brain and increased risk of death if they suffer a hemorrhagic stroke. view more (2008-09-30)
Genetics determine optimal drug dose of common anticoagulant
Genetic testing can be used to help personalize the therapeutic dosage of warfarin, a commonly-used anticoagulant, according to research published in the September 1, 2007, issue of Blood, the journal of the American Society of Hematology. This result represents one of the first applications of using an individual's genetic information to guide... view more... (2007-08-22)
Study shows optimal dose management of warfarin improves anticoagulation control
Researchers from Boston University School of Medicine (BUSM) have determined the optimal dose-management strategy to derive maximal benefit from warfarin therapy and improve patient outcomes. Results of the study appear online in the December 2008 issue of the Journal of Thrombosis and Haemostasis. view more (2008-12-23)
Mutant rats resist warfarin
A new series of mutations have been discovered that allow rats to resist the effects of the popular poison warfarin. Research published in the open access journal BMC Genetics describes eighteen new genetic changes found in rats from four continents. view more (2009-02-06)
Welcome Alternative To Warfarin For People At High Risk Of Stroke (pp 1686, 1691)
Results of an international study in this week's issue of THE LANCET provide strong evidence that the oral direct thrombin-inhibitor ximelagatran could be a safe and effective alternative to warfarin in reducing stroke among people with atrial fibrillation. Atrial fibrillation (irregular and rapidly beating atria) increases the risk of cardiac... view more... (2003-11-19)
Chamomile tea and lotion causing internal bleeding in patient on anti-coagulant medication
Researchers at the MUHC in Montreal have documented a severe case of internal hemorrhaging in a patient that drank chamomile tea and used chamomile lotion while taking anti-coagulant medication for a heart condition. view more (2006-04-28)
American College of Medical Genetics responds to new FDA labeling decision for warfarin
On August 16, the Food and Drug Administration approved new labeling information for the blood-thinner warfarin, sold under the brand name Coumadin. view more (2007-08-27)
Vitamin K discovery may lead to new treatments for patients at risk from blood clots
Medical Research Council (MRC) scientists have discovered more about the role that vitamin K plays in the complicated process of how blood clots. Their work, published in Nature, may lead to new treatments for patients at risk from blood clots, including those who have had heart attacks, have coronary artery disease, irregular heart beats, or have... view more... (2004-02-04)
Is it reasonable to perform polypectomy without interruption of anticoagulation?
Currently, patients taking anticoagulants to prevent stroke and blood clots are often recommended to stop these medications in order to perform colonoscopy with removal of polyps. view more (2009-05-08)
Common blood thinner increases risk of bone fracture
Elderly patients taking the commonly prescribed blood thinner warfarin experience an increased risk for osteoporosis-linked bone fractures, according to a study at Washington University School of Medicine in St. Louis. view more (2006-01-24)
Genetic testing not cost-effective in guiding initial dosing of common blood thinner
New analyses led by the University of Cincinnati (UC) show that genetic testing used to guide initial dosing of the blood-thinner warfarin may not be cost-effective for typical patients with atrial fibrillation but may be for patients at higher risk for major bleeding. view more (2009-01-20)
New method identifies rat poison in humans
Researchers at the Norwegian Institute of Public Health (NIPH) have developed a method to identify bromadiolone poisoning in humans. Bromadiolone is a rat poison that can be purchased freely in shops. A number of cases have been reported internationally where people have been poisoned, with a mortality rate of 20 percent. view more (2008-05-28)
Better instructions reduce complications among patients using common blood thinner
Patients who report receiving written and verbal instructions on the proper way to take the blood thinner warfarin are significantly less likely to suffer the serious gastrointestinal and brain bleeding problems that are associated with misuse of the drug, according to new research from the University of Pennsylvania School of Medicine. view more (2008-10-28)
As medicine targets personal DNA profiles, York researchers examine ethics and patient experiences
Researchers at the University of York are beginning a major study into the ethical and personal issues raised by a potential revolution in healthcare, which could incorporate individualised medical care - pharmacogenetics - into clinical practice. The use of genetic testing as a routine part of medical treatment opens exciting horizons, but brings... view more... (2004-08-04)
DNA research taking guesswork out of finding the 'therapeutic window'
It's only spit, but what's inside your saliva may help solve a dosing dilemma facing doctors and patients. view more (2008-10-24)
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