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New models question old assumptions about how many molecules it takes to control cell division
A single cell - whether a yeast cell or one of your cells - is exquisitely sensitive to its surroundings. It receives input signals, processes the information, makes decisions, and issues commands for making the proper response.   view more (2009-02-25)

Breakthrough in combating the side effects of Quinine
Discovered back in the 1600s quinine was the first effective treatment in the fight against malaria - and it continues to be a commonly used treatment against this devastating disease.   view more (2009-06-30)

Genetic sleuth solves glaucoma mystery
Dr. Michael Walter is one good gumshoe. The University of Alberta medical geneticist has cracked the case of WDR36, a gene linked to glaucoma.   view more (2009-03-20)

MIT applies engineering approach to studying biological pathways
An MIT team has used an engineering approach to show that complex biological systems can be studied with simple models developed by measuring what goes into and out of the system.   view more (2008-02-07)

Genome research centre opens on University of Sussex campus
Eight teams of cancer researchers have moved into the first research laboratory to be built on the University of Sussex campus for 30 years. Researchers in the purpose-built Genome Damage and Stability Centre are working on the human body's most precious possessions - genomes - which contain the genetic blueprint that tells every part of the body... view more... (2002-04-15)

Genes identified that protect against heart damage from chemotherapy
A series of genes that protect cells from the powerful, common chemotherapeutic agent doxorubicin has been identified by researchers working to understand how the drug also can destroy the heart.   view more (2007-12-04)

Researchers at Case Western Reserve discover a new way the body fights fungal infection
A team of researchers led by Amy G. Hise, M.D., M.P.H., assistant professor at the Center for Global Health and Diseases, Case Western Reserve University School of Medicine, is the first to discover how the body fights off oral yeast infections caused by the most common human fungal pathogen, Candida.    view more (2009-06-12)

Researchers uncover details about how dietary restriction slows down aging
University of Washington scientists have uncovered details about the mechanisms through which dietary restriction slows the aging process.   view more (2008-04-18)

Scientists Uncover Rules for Gene Amplification
Gene amplification plays an important role in causing cancers via activation of oncogenes.   view more (2006-06-30)

Protein transport in mitochondria revealed
The TIM23 complex, which regulates the transport of protein to the mitochondria in a cell, is much more complicated than was previously believed. This is shown by Uppsala University researcher Maria Lind in an article in the leading journal Cell.   view more (2005-03-31)

Single molecular 'mark' seen as pivotal for genome compaction in spores and sperm
In higher order animals, genetic information is passed from parents to offspring via sperm or eggs, also known as gametes. In some single-celled organisms, such as yeast, the genes can be passed to the next generation in spores.   view more (2006-09-18)

Scientists identify prion's infectious secret
Researchers have known for decades that certain neurodegenerative diseases, such as mad cow disease or its human equivalent, Cruetzfeldt-Jakob disease, result from a kind of infectious protein called a prion.   view more (2007-05-10)

WPI Researchers Take Aim at Hard-to-Treat Fungal Infections
A team of researchers at the Worcester Polytechnic Institute (WPI) Life Sciences and Bioengineering Center at Gateway Park has developed a new model system to study fungal infections.   view more (2009-11-20)

Brittle prions are more infectious
Brittleness is often seen as a sign of fragility. But in the case of infectious proteins called prions, brittleness makes for a tougher, more menacing pathogen.   view more (2006-06-29)

Caltech engineers build mini drug-producing biofactories in yeast
Researchers at the California Institute of Technology have developed a novel way to churn out large quantities of drugs, including antiplaque toothpaste additives, antibiotics, nicotine, and even morphine, using mini biofactories--in yeast.   view more (2008-08-18)

Scripps research team develops new technique to tap full potential of antibody libraries
In hopes of more fully tapping the libraries' potential, a group of Scripps Research Institute scientists, led by Scripps Research President Richard A. Lerner, M.D., has for the first time developed a new screening technique that enables antibody screening against equally massive libraries of targets.   view more (2009-01-16)

Introducing the biology of the future: Researchers at CellZome AG and EMBL publish record-breaking analysis of a cell's proteome
Scientists are calling it "biology of the next generation," and a major step towards transforming information from genome projects into applications such as the discovery of new drugs. Today researchers from Heidelberg have announced the completion of a large-scale study of the "molecular machines" formed by nearly two thousand... view more... (2002-01-08)

Fox Chase Researchers Give Mutants Another Chance
Researchers at Fox Chase Cancer Center have demonstrated that it might be possible to treat genetic diseases, including some forms of cancer, by "rescuing" the misshapen, useless proteins produced by some mutant genes.   view more (2009-02-12)

Shilatifard and colleagues clarify the enzymatic activity of factors involved in childhood leukemia
The Stowers Institute's Shilatifard Lab and colleagues have provided new insight into the molecular basis for H3K4 methylation, an activity associated with the MLL protein found in chromosomal translocation-based aggressive infant acute leukemias.   view more (2009-05-05)

Genetic interactions are the key to understanding complex traits
In recent years, genetic studies have uncovered hundreds of DNA variations linked to common diseases, such as cancer or diabetes, raising the prospect that scientists can gauge disease risk based on information in an individual's genome.   view more (2009-01-23)
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