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Alzheimer cell death in Zebrafish: Demise of neurons observed live for the first time
Extensive death of nerve cells leads to severe dementia in patients with Alzheimer's disease. Until now, it has only been possible to investigate the neuronal devastation in post mortem animal models, and by using complicated methods.   view more (2009-04-15)

Deadly genetic disease prevented before birth in zebrafish
By injecting a customized "genetic patch" into early stage fish embryos, researchers at Washington University School of Medicine in St. Louis were able to correct a genetic mutation so the embryos developed normally.   view more (2008-03-24)

Fish get insomnia, eyes wide open, say Stanford sleep researchers
Scientists at the Stanford University School of Medicine have hooked a fish that suffers from insomnia in their quest to understand the genetics behind sleep disorders.   view more (2007-10-16)

Zebrafish to shed light on human mitochondrial diseases
Zebrafish can now be used to study COX deficiencies in humans, a discovery that gives scientists an unprecedented window to view the earliest stages of mitochondrial impairments that lead to potentially fatal metabolic disorders.   view more (2007-09-14)

MicroRNAs help zebrafish regenerate fins
Biologists have discovered a molecular circuit breaker that controls a zebrafish's remarkable ability to regrow missing fins, according to a new study from Duke University Medical Center.   view more (2008-03-17)

Fast and slow — How the spinal cord controls the speed of movement
Using a state-of-the-art technique to map neurons in the spinal cord of a larval zebrafish, Cornell University scientists have found a surprising pattern of activity that regulates the speed of the fish's movement.   view more (2007-03-01)

UK research could lead to new treatments for Parkinson's
A team at the University of Sheffield has received a share of $3.6m from the Michael J. Fox Foundation to research potential causes and treatments for Parkinson's Disease.   view more (2005-01-28)

Fat fish put obesity on the hook
Everyone knows that eating lean fish helps slim waistlines, but researchers from the Center for the Study of Weight Regulation and Associated Disorders at Oregon Health and Science University in Portland, OR, have found a new way fish can help eliminate obesity.   view more (2007-06-19)

Key to zebrafish heart regeneration uncovered
When a portion of a zebrafish's heart is removed, the dynamic interplay between a mass of stem cells that forms in the wound and the protective cell layer that covers the wound spurs the regeneration of functional new heart tissue.   view more (2006-11-03)

Jefferson researchers find nanoparticle shows promise in reducing radiation side effects
Using transparent zebrafish embryos, researchers at Jefferson Medical College have shown that a microscopic nanoparticle can help fend off damage to normal tissue from radiation.   view more (2005-11-15)

A fisheye view of the deadliest breast cancer
Inflammatory breast cancer (IBC) is the deadliest form of the disease, with fewer than half of those diagnosed today having a five-year prognosis for survival.   view more (2006-12-13)

Chronic Alcohol Exposure Can Affect Brain Protein Expression
Researchers at the University at Buffalo studying the effects of alcohol on the brain, using zebrafish as a model, have identified several novel central nervous system proteins that are affected by chronic alcohol exposure.   view more (2006-08-30)

Transport interrupted — Texas A&M biologists trace cause of early blindness to tissue defect
Researchers at Texas A&M University are shedding light on a rare form of early blindness, identifying the cells involved and paving the way for possible therapies to treat or even prevent what is currently an incurable disease.   view more (2007-03-08)

With a flash of light, a neuron's function is revealed
There's a new way to explore biology's secrets. With a flash of light, scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory and the University of California, Berkeley zeroed in on the type of neural cell that controls swimming in larval zebrafish.   view more (2009-09-17)

Mutated gene in zebrafish sheds light on blindness in humans
Among zebrafish, the eyes have it. Inside them is a mosaic of light-sensitive cells whose structure and functions are nearly identical to those of humans.   view more (2009-03-25)

Oregon researchers show how resident bacteria shape gut development
University of Oregon researchers have shown that bacteria residing in the intestine shape gut development by means of several distinct signaling mechanisms.   view more (2006-06-22)

Geisinger scientist seeks cure for Lou Gehrig's disease, creating device to find treatment
A small tropical fish, the curiosity of a Geisinger research scientist and some college students have created the perfect storm of sorts in an attempt to find a cure for one of the world's most devastating neurological diseases.   view more (2007-07-31)

The hormone of darkness: melatonin could hurt memory formation at night
What do you do when a naturally occurring hormone in your body turns against you? What do you do when that same hormone - melatonin - is a popular supplement you take to help you sleep? A University of Houston professor and his team of researchers may have some answers.   view more (2007-11-16)

Study fishes out new role for prostaglandins
Prostaglandins - the fat-derived compounds linked to pain, inflammation, reproduction and cancer - can add another biological function to their extensive catalog.   view more (2006-01-03)

Malignant melanoma cells secrete protein required for embryo formation
A Northwestern University research group has discovered that aggressive melanoma cells secrete Nodal, a protein that is critical to proper embryo formation.   view more (2006-07-31)
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