Zebrafish Current Events | Zebrafish News | 3
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Lipids play important role in nervous system development
Blocking a signaling lipid can keep nerves from developing the arm-like extensions they need to wire the body and may even cause neurons to die, researchers have found. view more (2005-10-25)
Reversing cancer cells to normal cells
In earlier work, Northwestern University scientist Mary J.C. Hendrix and colleagues discovered that aggressive melanoma cells (but not normal skin cells nor less aggressive melanoma cells) contain specific proteins similar to those found in embryonic stem cells. view more (2007-04-30)
Study reveals a key to blood vessel growth and possible drug target
Researchers have identified a molecular pathway that plays a critical role in the growth of blood vessels. The finding not only offers an important insight into the development of the vascular system during embryonic development but suggests a potential target for inhibiting the blood vessels that fuel cancers, diabetic eye complications and... view more... (2007-10-15)
Primordial fish had rudimentary fingers
Tetrapods, the first four-legged land animals, are regarded as the first organisms that had fingers and toes. Now researchers at Uppsala University can show that this is wrong. Using medical x-rays, they found rudiments of fingers in the fins in fossil Panderichthys, the "transitional animal," which indicates that rudimentary fingers... view more... (2008-09-22)
How does a zebrafish grow a new tail?
If a zebrafish loses a chunk of its tail fin, it'll grow back within a week. Like lizards, newts, and frogs, a zebrafish can replace surprisingly complex body parts. A tail fin, for example, has many different types of cells and is a very intricate structure. It is the fish version of an arm or leg. view more (2006-12-27)
A screening strategy using zebrafish targets genes that protect against hearing loss
A small striped fish is helping scientists understand what makes people susceptible to a common form of hearing loss, although, in this case, it's not the fish's ears that are of interest. view more (2008-03-03)
More 'functional' DNA in genome than previously thought
Surrounding the small islands of genes within the human genome is a vast sea of mysterious DNA. While most of this non-coding DNA is junk, some of it is used to help genes turn on and off. view more (2007-12-12)
Hydrogen peroxide marshals immune system
When you were a kid your mom poured it on your scraped finger to stave off infection. view more (2009-06-04)
Role for microRNAs in limb regeneration
In the March 15th issue of G&D, Dr. Kenneth Poss (Duke University Medical Center) and colleagues reveal that microRNA depletion is a necessary step in tissue regeneration - a discovery with interesting implications for their use in regenerative medicine. view more (2008-03-17)
Zebrafish enable scientists to study the migration of neurons that enable sexual maturity
Scientists are watching a small group of neurons that enable sexual maturity and fertility make a critical journey: from where they form, near the developing nose, to deep inside the brain. view more (2008-06-05)
International team discovers gene associated with epilepsy
A University of Iowa-led international research team has found a new gene associated with the brain disorder epilepsy. view more (2008-11-18)
Zebrafish may help solve ringing in vets' ears
Ernest Moore, an audiologist and cell biologist at Northwestern University, developed tinnitus -- a chronic ringing and whooshing sound in his ears -- twenty years ago after serving in the U.S. Army reserves medical corps. view more (2008-05-01)
Novel method to reveal drug targets
Wellcome Trust Sanger Institute scientists have developed a new large-scale method to identify the interactions between proteins that are a major target for therapeutic intervention. view more (2008-02-25)
Starting over: Wnt reactivates dormant limb regeneration program
Chop off a salamander's leg and a brand new one will sprout in no time. But most animals have lost the ability to replace missing limbs. Now, a research team at the Salk Institute for Biological Studies has been able to regenerate a wing in a chick embryo - a species not known to be able to regrow limbs-suggesting that the potential for such... view more... (2006-11-20)
Penn Study Provides First Clear Idea of How Rare Bone Disease Progresses
An international team of scientists, led by researchers at the University of Pennsylvania School of Medicine, is taking the first step in developing a treatment for a rare genetic disorder called fibrodysplasia ossificans progressiva (FOP), in which the body's skeletal muscles and soft connective tissue turns to bone, immobilizing patients over a... view more... (2009-11-13)
What do blood stem cells need to grow? Blood flow
Blood stem cells literally go with the flow, according to a new report published as an immediate early publication in the journal Cell, a Cell Press journal, on May 13th. view more (2009-05-14)
Newly found enzymes may play early role in cancer
Researchers have discovered two enzymes that, when combined, could be involved in the earliest stages of cancer. Manipulating these enzymes genetically might lead to targeted therapies aimed at slowing or preventing the onset of tumors. view more (2008-12-29)
Regulatory molecule for tumor formation or suppression identified by Singapore, US researchers
One of the small regulatory molecules, named microRNA-125b, is a novel regulator of p53, an important protein that safeguards cells against cancers, Singapore and U.S. scientists report in the March 17, 2009 issue of the journal Genes & Development. view more (2009-03-18)
Cellular traffic backups implicated in skeletal malformations
A defective link in the intracellular protein "transit system" may lie at the heart of some craniofacial defects, new research in zebrafish suggests. view more (2006-09-19)
MicroRNA undermines tumor suppression
Scientists at the Whitehead Institute for Biomedical Research and the National University of Singapore have discovered the first microRNA (miRNA) capable of directly tamping down the activity of the well known tumor-suppressor gene, p53, While p53 functions to prevent tumor formation, the p53 gene is thought to malfunction in more than 50% of... view more... (2009-03-18)
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