Zebrafish Current Events | Zebrafish News | 4
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Promising new drug targets identified for Huntington's disease
Research funded by the Wellcome Trust has provided a number of promising new drug targets for Huntington's disease, a neurodegenerative disease. Scientists at the University of Cambridge have identified a number of candidate drugs to investigate further which encourage cells to "eat" the malformed proteins that lead to the disease. view more (2008-03-24)
Big-Hearted Fish Reveals Genetic Underpinnings of Enigmatic Cardiovascular Condition, According to Penn Study
Researchers at the University of Pennsylvania School of Medicine have unlocked the mystery of a puzzling human disease and gained insight into cardiovascular development, all thanks to a big-hearted fish. view more (2009-02-26)
Pitt-led Research Provides Insight Into Development of Common Congenital Circulatory Defects
University of Pittsburgh-led researchers could provide new insight into how two common congenital circulatory problems-aortic arch deformity and arteriovenous malformations (AVMs)-develop in humans, as reported in the June 15 edition of Developmental Biology. view more (2008-07-09)
Genetic research unveils common origins for distinct clinical diagnoses
Researchers at Johns Hopkins have discovered that two clinically different inherited syndromes are in fact variations of the same disorder. Reporting in the April issue of Nature Genetics, the team suggests that at least for this class of disorders, the total number and "strength" of genetic alterations an individual carries throughout... view more... (2008-03-10)
Embryology Study Offers Clues to Birth Defects
Gregg Duester, Ph.D., professor of developmental biology at Burnham Institute for Medical Research (Burnham), along with Xianling Zhao, Ph.D., and colleagues, have clarified the role that retinoic acid plays in limb development. view more (2009-06-10)
In early embryos, cilia get the message across
Having your heart in the right place usually means having it located on the left side of your body. But just how a perfectly symmetrical embryo settles on what's right and what's left has fascinated developmental biologists for a long time. view more (2006-10-23)
New insight into most common forebrain malformation
St. Jude Children's Research Hospital scientists have identified one of the molecular mechanisms underlying the genetic brain malformation called holoprosencephaly (HPE). The findings not only yield insights into the most common developmental malformation of the anterior brain and face in newborns, but also help in understanding the intricate... view more... (2008-08-12)
The Jetlag of a Glowing Fish and More: Press Release from PLoS Biology
What Does an Airline Traveler Have in Common with a Glowing Fish? In William Gibson's novel Pattern Recognition, the protagonist posits a theory of jet lag: "Souls can't move that quickly, and are left behind, and must be awaited, upon arrival, like lost luggage." Science has yet to address the issue of a spiritual speed limit,... view more... (2005-01-25)
Bloodless Worm Sheds Light on Human Blood, Iron Deficiency
Using a lowly bloodless worm, University of Maryland researchers have discovered an important clue to how iron carried in human blood is absorbed and transported into the body. The finding could lead to developing new ways to reduce iron deficiency, the world's number one nutritional disorder. view more (2008-04-17)
Embryo's heartbeat drives blood stem cell formation
Biologists have long wondered why the embryonic heart begins beating so early, before the tissues actually need to be infused with blood. view more (2009-05-14)
Mutant gene causes severe kidney disease in infants
Scientists at the University of Michigan Medical School have discovered a previously unknown cause for a severe, early-onset form of kidney disease and renal failure in children: recessive mutations in a gene called phospholipase C epsilon or PLCE1. view more (2006-11-06)
Researchers find lack of key molecule leads to deafness
Researchers have identified tiny molecules that may lead to big breakthroughs in the treatment of hearing loss and deafness. view more (2009-04-17)
Study will explore genetics of congenital limb and heart malformations
New research published in the August issue of the Journal of Cell Biology explains for the first time why congenital heart defects so often occur with limb deformities. view more (2006-08-21)
Cilia: small organelles, big decisions
Johns Hopkins researchers say they have figured out how human and all animal cells tune in to a key signal, one that literally transmits the instructions that shape their final bodies. view more (2007-10-04)
Fish eyes could hold clue to repairing damaged retinas in humans
A special type of cell found in the eye has been found to be very important in regenerating the retina in zebrafish and restoring vision even after extensive damage. view more (2007-08-01)
Study sheds light on signaling mechanism in stem cells, cancer
UCSF scientists have illuminated a key step in a signaling pathway that helps orchestrate embryonic development. view more (2005-10-26)
A surprise 'spark' for pre-cancerous colon polyps
Researchers at Huntsman Cancer Institute (HCI) at the University of Utah studied the events leading to colon cancer and found that an unexpected protein serves as the "spark" that triggers formation of colon polyps, the precursors to cancerous tumors. view more (2009-05-15)
EMBO supports researchers from emerging economies
The first fellows benefiting from the European Molecular Biology Organization's (EMBO) new World Programme fellowship scheme will start their work in their guest laboratories from now on. The four selected researchers come from Bangladesh, Brazil, Cuba and India and will visit German or Israeli laboratories for six or nine months: * Miah Bari... view more... (2002-11-08)
Cost-effective method for gene silencing is featured in Cold Spring Harbor Protocols
Nearly a decade ago, now-Nobel laureates Craig Mello and Andrew Fire discovered that they could insert short RNA molecules into worms and shut down specific genes. view more (2007-08-02)
Cholesterol could be key to treating fetal alcohol syndrome
Small amounts of alcohol can interfere with the growth of a fetus, but added cholesterol may help prevent a wide array of neurological and physical defects from alcohol exposure, according to a new study in laboratory fish. view more (2007-03-09)
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