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Chromosomal abnormalities in sperm higher after vasectomy reversal
Men who have had a vasectomy reversed have a very much greater rate of chromosomal abnormalities in their sperm than do normal fertile men. view more (2006-06-21)
Researchers identify new drug targets for cancer
Solving a 100-year-old genetic puzzle, researchers at the University of California, San Diego (UCSD) School of Medicine have determined that the same genetic mechanism that drives tumor growth can also act as a tumor suppressor. view more (2007-01-02)
Common viruses may cause cancer
In some cases, the fusion of human cells is a normal process that leads, for instance, to the formation of muscle and bone. Viral infections can also cause cell fusion, but cells fused by viruses are widely considered to be harmless because they are generally believed to die without consequences for the host. view more (2005-11-09)
MIT sheds light on how tumor cells form
MIT cancer researchers have discovered a process that may explain how some tumor cells form, a discovery that could one day lead to new therapies that prevent defective cells from growing and spreading. view more (2006-06-22)
'Signature' of chromosome instability predicts cancer outcomes
Microscopic examination of tumor specimens cannot always predict a cancer's aggressiveness, leading to increased interest in molecular approaches to diagnosis. view more (2006-08-21)
New study finds amniocentesis safer for pregnant women
Amniocentesis is the most commonly prescribed invasive test performed during pregnancies in the United States. view more (2006-11-01)
New method of testing eggs for abnormalities could solve problems of embryo freezing
Italian researchers have shown for the first time that it is possible to test a woman's egg, before fertilisation, for chromosomal abnormalities that might make an embryo less likely to implant successfully or more likely to miscarry at a later stage. view more (2006-06-19)
Double identities lie behind chromosome disorders
Chromosome disorders in sex cells cause infertility, miscarriage and irregular numbers of chromosomes (aneuploidy) in neonates. A new study from Karolinska Institutet published in the scientific journal Nature Genetics shows how chromosome disorders can arise when sex cells are formed. view more (2007-07-09)
Levels of folate in men's diets is linked to chromosomal abnormalities in their sperm
Researchers have found an association between a vitamin found in leafy green vegetables, fruit and pulses and levels of chromosomal abnormalities in men's sperm. Men who consumed high levels of folate (a water-soluble B vitamin that occurs naturally in food) and folic acid (the synthetic form of the vitamin) tended to have lower levels of abnormal... view more... (2008-03-20)
Support for chromosomal theory of cancer found in cancers' development of drug resistance
Thirty-six years into the war on cancer, scientists have not only failed to come up with a cure, but most of the newer drugs suffer from the same problems as those available in the pre-war days: serious toxicity, limited effectiveness and eventual resistance. view more (2007-06-28)
Study links dietary folate intake to genetic abnormalities in sperm
Healthy men who report lower levels of the nutrient folate in their diets have higher rates of chromosomal abnormalities in their sperm, according to a new study by researchers at the University of California, Berkeley, and the Lawrence Berkeley National Laboratory. view more (2008-03-20)
'QUADRUPLE TEST' OFFERS BEST PREDICTION FOR DOWN'S SYNDROME (pp 794, 835)
Authors of a research letter in this week's issue of THE LANCET highlight how screening for Down's syndrome based on maternal age and four markers in maternal blood should be used worldwide-the quadruple test is far more effective than screening based on maternal age alone. Screening for Down's syndrome is widely practised early in the second... view more... (2003-03-05)
New blood test for Down syndrome
Howard Hughes Medical Institute researchers have developed a new prenatal blood test that accurately detected Down syndrome and two other serious chromosomal defects in a small study of 18 pregnant women. view more (2008-10-07)
Geneticists aim to develop test to identify learning disability
Clinical geneticist and principal investigator Dr David FitzPatrick explains: "In approximately 10% of CGMH cases, the condition will be caused by a chromosomal abnormality such as a chromosome 21 problem as in Down's Syndrome. Recent studies have suggested that a further 6% of cases may be caused by tiny sub-microscopic abnormalities at the ends... view more... (2000-01-20)
When you've doubled your genes, what's 1 chromosome more or less?
An individual with Down syndrome and a male calico cat have one thing in common-each has an extra chromosome. For animals, most instances of an extra chromosome result in birth defects or even death, but plants are another matter entirely. view more (2009-09-15)
Chromosomal problems affect nearly all human embryos
For the first time, scientists have shown that chromosomal abnormalities are present in more than 90% of IVF embryos, even those produced by young, fertile couples. view more (2009-07-01)
Protein helps cells duplicate correctly, avoid becoming cancer
A Purdue University researcher has discovered that the absence of certain proteins needed for proper cell duplication can lead to cancer. view more (2009-10-06)
New research finds possible genetic link to cause of pregnancy loss and disorders
Scientists at the University of Tennessee, Knoxville, and Lawrence Berkeley National Laboratory (LBNL) have published new findings about a cause of a condition at the root of genetic disorders such as Down Syndrome, pregnancy loss and infertility. view more (2009-07-22)
Research sheds light on cause of Down syndrome and other genetic disorders
Scientists have a better understanding of what causes an abnormal number of chromosomes in offspring, a condition called aneuploidy that encompasses the most common genetic disorders in humans, such as Down syndrome, and is a leading cause of pregnancy loss. view more (2009-07-20)
New test can detect both genetic and chromosomal abnormalities in embryos
One-step screening for both genetic and chromosomal abnormalities has come a stage closer as scientists announced that an embryo test they have been developing has successfully screened cells taken from spare embryos that were known to have cystic fibrosis. view more (2009-06-30)
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