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Data in New England Journal of Medicine show benefits of REMICADE in ulcerative colitis patients
Landmark studies published today in The New England Journal of Medicine demonstrate the benefits of treatment with REMICADE (infliximab) in patients with ulcerative colitis (UC). view more (2005-12-09)
New findings show Enbrel significantly reduced levels of C-reactive protein
Amgen (NASDAQ: AMGN) and Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE), today announced findings from a retrospective analysis, which demonstrated that ENBREL reduced C-reactive protein (CRP), a marker of inflammation, in patients with moderate to severe plaque psoriasis following 12 weeks of treatment. view more (2008-02-04)
Where do new therapies work best?
An observational study to investigate how new therapies for rheumatic diseases perform across different conditions has revealed that they may be more successful in certain conditions. view more (2006-06-23)
Largest ever study of genetics of common diseases published today
The Wellcome Trust Case Control Consortium, the largest ever study of the genetics behind common diseases such as diabetes, rheumatoid arthritis and coronary heart disease, today publishes its results in the journals Nature and Nature Genetics. view more (2007-06-07)
NICE gives backing for the use of advanced biological therapies to treat severe psoriasis
The UK National Institute for Health and Clinical Excellence (NICE) has today issued guidance for the use of the targeted biological therapies, Enbrel® (etanercept) and Raptiva® (efalizumab), to treat adult patients with severe plaque psoriasis. view more (2006-07-27)
Improving the standard of rheumatology care in Europe
The Annual European Congress of Rheumatology commenced today with a comprehensive set of recommendations which aim to clarify treatment options for a range of debilitating rheumatic conditions. view more (2006-06-22)
Monoclonal antibody reduces exacerbations in asthmatics
Patients with symptomatic moderate asthma who were treated with anti-tumor necrosis factor alpha, an anti-inflammatory monoclonal antibody, experienced significantly fewer disease exacerbations than individuals taking a placebo. view more (2006-10-02)
Major genetic breakthrough for ankylosing spondylitis brings treatment hope
Research funded by the Wellcome Trust and the Arthritis Research Campaign has identified two genes implicated in the disease ankylosing spondylitis, a common disease primarily causing back pain and progressive stiffness. view more (2007-10-22)
Study reveals 2 genes linked to disabling arthritis
An international team of researchers led by a Fred Hutchinson Cancer Research Center geneticist has discovered two genes linked to a disabling form of arthritis called ankylosing spondylitis, a painful and progressive disease in which some or all of the spine's vertebrae fuse together. view more (2007-10-22)
Clinical studies show REMICADE reduces incidence of bowel surgeries in ulcerative colitis patients
Clinical data presented today at the annual meeting of the American College of Gastroenterology (ACG) show that REMICADE significantly reduces the incidence of colectomy surgeries for patients with moderately to severely active ulcerative colitis (UC). view more (2007-10-16)
New Discovery in Preventing Diabetic Complications
A new study sheds light on the response to infection in people with type 2 diabetes. These individuals develop diabetes associated with obesity. Findings from this study revealed that controlling a specific protein produced by the body, known as a cytokine, reduces the expression of other molecules and helps control inflammation. This is... view more... (2004-08-23)
TNF-Alpha Blocker Infliximab Highly Effective For Patients With Ankylosing Spondylitis
BERLIN, Germany - 6 April 2002 -- For the first time, there is a therapy that can significantly reduce disease activity for the majority of patients with ankylosing spondylitis (AS), a chronic inflammatory rheumatic disease that often leads to stiffening and subsequent fusion of the spine. The study, published in the April 6 issue of "The... view more... (2002-04-05)
UT Rheumatologists Discover Two Genes
Work done in part by researchers at The University of Texas Medical School at Houston has led to the discovery of two genes that cause ankylosing spondylitis, an inflammatory and potentially disabling disease. The findings are published in the Oct. 21 online edition of Nature Genetics, a journal that emphasizes research on the genetic basis for... view more... (2007-10-22)
Phase 3 data show golimumab improved psoriatic arthritis symptoms
Patients with active psoriatic arthritis receiving monthly subcutaneous (SC) injections of golimumab (CNTO 148) experienced significant and sustained improvements in the joint and skin manifestations of the disease. view more (2007-11-08)
Golimumab significantly reduced signs and symptoms of ankylosing spondylitis
More than half of patients receiving monthly subcutaneous (SC) injections of golimumab (CNTO 148) 50 mg and 100 mg experienced significant and sustained improvements in the signs and symptoms of active ankylosing spondylitis, according to Phase 3 study results presented at the American College of Rheumatology (ACR) annual meeting. view more (2007-11-08)
CV risk management should be mandatory in RA and other types of inflammatory rheumatic disease
Rheumatoid arthritis (RA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA) patients should undergo compulsory cardiovascular (CV) risk management and existing CV risk calculators should be adapted to the increased CV risk in inflammatory rheumatic disease patients. view more (2008-06-16)
Infliximab May Offer Hope For Patients Living With Spondyloarthropathy
For the first time, there may be an effective therapeutic option for severe cases of spondyloarthropathies (SpA), a group of rheumatic inflammatory diseases that affect the spinal column, peripheral joints and tendons. The study, published in the March 6 issue of "Arthritis and Rheumatism", found that patients treated with infliximab (also known... view more... (2002-03-07)
Study aims to induce recovery from ankylosing spondylitis
Chinese patients will soon have the opportunity to take part in a study of a novel therapy aimed at reversing the autoimmune disease, ankylosing spondylitis. view more (2009-07-22)
Diagnosis of arthritis 5 years earlier in childless women compared to those with children
Nulliparous women (those who have not given birth to children) are diagnosed with chronic arthritides (including ankylosing spondylitis, psoriatic arthritis and rheumatoid arthritis (RA) an average of 5.2 years before parous women (those who have given birth to children). view more (2009-06-12)
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