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Childhood cancer survivors at increased risk of sarcoma
Survivors of childhood cancers have a ninefold increased risk of developing a secondary sarcoma—a cancer of connective or supportive tissue such as bone, fat, or muscle—compared with the general population. view more (2007-02-21)
Genes raise risk of heart disease after treatment for childhood cancer
Gene variations may raise the risk that survivors of childhood cancer will suffer congestive heart failure as a complication of drugs they received during cancer treatment. view more (2006-06-05)
Study analyzes heart attack mortality risk associated with Hodgkin disease treatments
Doctors have long known that patients treated for Hodgkin disease are at an increased risk for heart attacks. view more (2007-02-07)
Anthracyclines improve survival in HER2-positive breast cancer patients
Treatment with the class of chemotherapy drugs called anthracyclines improves survival in women with HER2-positive breast cancer who have previously had surgery, but it may not offer any benefit for women with HER2-negative tumors. view more (2007-12-26)
How chemotherapy drugs block blood vessel growth, slow cancer spread
Researchers at the Johns Hopkins University School of Medicine have discovered how a whole class of commonly used chemotherapy drugs can block cancer growth. view more (2009-01-23)
Avoiding heart failure after cancer drugs - new hope for early diagnosis, treatment and prevention of cardiotoxicity
New hope that heart failure - a potentially fatal side effect of some types of cancer drugs - can be diagnosed early and successfully treated or even prevented, is reported today (Thursday 2 May) in Annals of Oncology, journal of the European Society for Medical Oncology. A team from the University of Milan* has found evidence that elevated blood... view more... (2002-04-28)
Standard chemo works better against metastatic BRCA1/2 breast cancer than against sporadic tumors
The first study to investigate the effects of chemotherapy on metastatic breast cancer in women with the BRCA1 or BRCA2 gene mutation has shown that standard chemotherapy works better in these patients than in women without the BRCA1/2 mutation. view more (2008-04-17)
More children survive cancer but the after-effects present a challenge to doctors
Embargoed: 09.00 hrs CET Wednesday 24 September 2003 Copenhagen, Denmark: The number of children who survive childhood cancer is improving dramatically, but because of the side effects of their treatment the majority continue to need specialist care for many years. This rapid increase in the numbers of survivors means that the medical profession... view more... (2003-09-21)
Herceptin and chemo improves response rates without major adverse effects in HER2 breast cancer
Women with a particularly aggressive form of breast cancer seem to do better if they are treated with a combined anthracycline and taxane chemotherapy regimen before surgery, together with trastuzumab (Herceptin) before and after surgery, according to results from the largest multi-centre trial to investigate this treatment. view more (2008-04-18)
HER2 levels may aid in treatment selection for metastatic breast cancer
Findings published in the December 1, 2008, issue of Clinical Cancer Research, a journal of the American Association for Cancer Research, show lapatinib benefits women with HER2-positive breast cancer, while women with HER2-negative breast cancer or those who express EGRF alone derive no incremental benefit. view more (2008-12-03)
Triple drug combination is promising option to treat metastatic HER2+ breast cancer
Combining two chemotherapy drugs with trastuzumab (Herceptin) to treat women who have metastatic HER2+ breast cancer may offer physicians another choice in their treatment options. view more (2009-05-15)
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